N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivatives

ABSTRACT

The present invention relates to a method of protecting plants against attack or infestation by phytopathogenic organisms, such as nematodes or especially microorganisms, preferably fungi, bacteria and viruses, or combinations of two or more of these organisms, by applying at least one compound of the formula (I): wherein n is 0 or 1, R 1  is halogen, alkoxy, haloalkyl, haloalkoxy or alkyl, R 2  is hydrogen, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy, each of R 3 , R 4  and R 5  is, independently of the others, hydrogen, lower alkyl or halogen, and R 6  is as defined in claim  1.  The invention also relates to new compounds of formula (I), their preparation, use and compositions comprising said compound

This application is a 371 of International Application No. PCT/EP01/06389, filed Jun. 6, 2001, the contents of which are incorporated herein by reference.

The present invention relates to a method of protecting plants against attack or infestation by phytopathogenic organisms, such as nematodes or especially microorganisms, preferably fungi, bacteria and viruses, or combinations of two or more of these organisms, by administering an N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivative as specified hereinafter to a part and/or to the site of a plant, the use of said derivative for protecting plants against said organisms and compositions comprising said derivative. It further relates to novel N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivatives, their preparation, their use as mentioned above and compositions comprising them.

Certain N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivatives have already been described in PCT applications WO 95/09851 and WO 95/09853, useful for example for treating tumours.

Surprisingly, it has now been found that these and the additional new N-phenyl-4-(4-pyridyl)-2-pyrimidineamine are effective in plant protection and related areas, showing advantageous properties in the treatment of plant diseases caused by organisms.

The N-phenyl-4-(4-pyridyl)-2-pyrimidineamine derivatives to be used according to the invention are those of the formula I,

wherein

n is 0 or 1,

R₁ is halogen, alkoxy, haloalkyl, haloalkoxy or alkyl,

R₂ is hydrogen, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy,

each of R₃, R₄ and R₅ is, independently of the others, hydrogen, lower alkyl or halogen, and

R₆ is

-   a) hydrazino, that is unsubstituted or one- to threefold substituted     by optionally substituted alkyl and/or optionally substituted acyl, -   b) cyclohexylamino, tetrahydro-4H-pyranyl-4-amino,     pyrrolidine-3-amino, 2- or 3-tetrahydro-furylamino, all optionally     substituted by amino, hydroxy, alkoxy, alkyl or alkoxyalkyl, -   c) piperazinyl that is optionally substituted by amino, amino-lower     alkyl, hydroxy, alkoxy, alkyl or alkoxyalkyl, -   d) morpholinyl that is optionally substituted by amino, amino-lower     alkyl, hydroxy, alkoxy, alkyl or alkoxyalkyl, -   e) oxazolidinyl that is optionally substituted by amino, amino-lower     alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, -   f) thiazolidinyl that is optionally substituted by amino,     amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or     alkoxyalkyl, -   g) imidazolidinyl that is optionally substituted by amino,     amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or     alkoxyalkyl, -   h) amino or mono- or di-(lower alkyl)amino wherein the lower alkyl     moieties are unsubstituted or substituted by one or more (preferably     1 to 3, especially 1 or 2) substitutents independently selected from     the group consisting of unsubstituted amino, N-mono- or N,N-di-(lowe     ralkyl)-amino, (lower alkoxy)-lower alk-oxy, lower     alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower     alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower     alkylamino, cyano, halogen, oxo, hydroximino, alkoximino, optionally     substituted hydrazono, lower alkenyl, lower alkynyl, guanidyl, lower     alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower     alkanoylamino, halo-lower alkanoylamino, lower     alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino,     lower alkoxy-lower alkylaminocarbonylamino, amidino,     di-lower-alkylamino-cyclohexyl, carboxy, lower alkoxycarbonyl,     hydroxy-lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl,     lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower     alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower     alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy,     lower alkoxy-lower alkanoyloxy, carbamoyl, N-mono- or N,N-di-lower     alkylcarbamoyl, N-(hydroxy-lower alkyl)carbamoyl, N-lower     alkyl-N-hydroxy-lower alkylcarbamoyl, N,N-di-(hydroxy-lower     alkyl)-carbamoyl, N-hydroxy-carbamoyl, hydroxy, lower alkoxy, lower     alkenyloxy, lower alkinyloxy, lower haloalkoxy, lower alkylthio,     lower alkylsulfoxyl, lower alkylsulfonyl, lower alkoxysilyl,     4-tetrahydro-4H-pyranyl, 3-pyrrolidinyl, 2- or 3-tetrahydrofuryl, 2-     or 3-dihydrofuryl, piperazinyl, lower alkanoyl-piperazinyl     (including formylpiperazinyl), optionally substituted heteroaryl and     optionally substituted heteroaryloxy -   i) optionally substituted alkanoylamino, optionally substituted     alkenoylamino, optionally substituted alkynoylamino, optionally     substituted mono- or di-alkylaminocarbonylamino, optionally     substituted alkoxycarbonylamino, optionally substituted mono- or     di-alkylaminosulfonylamino, optionally substituted mono- or     di-alkylaminosulfoxylamino, -   j) N-(optionally substituted alkyl)-N-(optionally substituted lower     alkanoyl)-amino, -   k) N-(optionally substituted alkyl)-N-(optionally substituted     alkoxycarbonyl)-amino, -   l) N-(optionally substituted alkyl)-N-(N′,N′-mono- or di-[optionally     substituted alkyl]-aminocarbonyl)-amino, or -   m) N═C(R₇,R₈) wherein R₇ is hydrogen, alkyl, amino, mono- or     di-alkylamino and R₈ is amino, mono- or dialkylamino or wherein R₇     and R₈, together with the binding carbon atom, form a saturated     five- to seven-membered ring with 0, 1 or 2 ring nitrogen atoms that     is optionally substituted by one or more substituents, preferably 1     to 3 substituents, especially lower alkyl;     or a salt thereof.

The general symbols and expressions used above preferably are defined as below:

Halogen is fluorine, bromine, iodine or preferably chlorine.

Alkoxy is preferably C₁–C₁₆alkoxy, more preferably C₁–C₈alkoxy, especially lower alkoxy, and is linear or branched. Lower alkoxy is preferably methoxy or ethoxy.

Haloalkyl is preferably C₁–C₁₆alkyl, more preferably C₁–C₈alkyl, especially lower alkyl, that is linear or branched and is substituted by one or more, for example in the case of halo-ethyl up to six, halogen atoms, especially fluorine. Preferred is trifluoromethyl or 2,2,2-trifluoroethyl.

Haloalkoxy is preferably C₁–C₁₆alkoxy, more preferably C₁–C₈alkoxy, especially lower alkoxy, that is linear or branched and that is substituted by one or more, for example in the case of halo-ethyl up to five, halogen atoms, especially fluorine; trifluoromethoxy and 1,1,2,2-tetrafluoroethoxy are especially preferred.

Alkyl—as a group per se se and as a structural element of other groups and compounds, such as alkylamino, alkanoylamino, alkanoyloxy, alkylthio, alkylsulfoxyl, alkylsulfonyl—is preferably C₀–C₁₆alkyl, more preferably C₁–C₈alkyl, especially lower alkyl, and is linear i.e. methyl, ethyl, propyl, butyl, pentyl or hexyl, or branched one or more times, e.g. isopropyl, isobutyl, sec.-butyl, tert.-butyl, isopentyl, neopentyl or isohexyl. Lower alkyl is preferably methyl or ethyl.

Optionally substituted means that the respective moiety is unsubstituted (=bearing only hydrogen instead of a substitutent) or substituted by one or more, especially 1 to 3, substituents independently selected from the group consisting of amino, N-mono- or N,N-di-(lower alkyl)-amino, (lower alkoxy)-lower alk-oxy, lower alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower alkylamino, cyano, halogen, oxo bound to a carbon that is not directly bound to a heteroatom, hydroximino, alkoximino, optionally substituted hydrazono, lower alkenyl, lower alkynyl, guanidyl, lower alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower alkanoylamino, halo-lower alkanoylamino, lower alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino, lower alkoxy-lower alkylaminocarbonylamino, amidino, di-lower-alkylamino-cyclohexyl, carboxy, lower alkoxycarbonyl, hydroxy-lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl, lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy, lower alkoxy-lower alkanoyloxy, carbamoyl, N-mono- or N,N-di-lower alkylcarbamoyl, N-(hydroxy-lower alkyl)carbamoyl, N-lower alkyl-N-hydroxy-lower alkyl-carbamoyl, N,N-di-(hydroxy-lower alkyl)-carbamoyl, N-hydroxy-carbamoyl, hydroxy, lower alkoxy, lower alkenyloxy, lower alkinyloxy, lower haloalkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxysilyl, 4-tetrahydro-4H-pyranyl, 3-pyrrolidinyl, 2- or 3-tetrahydrofuryl, 2- or 3-dihydrofuryl, piperazinyl, lower alkanoyl-piperazinyl (including formylpiperazinyl), optionally substituted heteroaryl and optionally substituted heteroaryloxy (with the proviso that in the case of optionally substituted heteroaryl and optionally substituted heteroaryloxy a heteroaryl substituent is preferably not substituted by substituted heteroaryloxy). Preferred substituents are lower alkoxy, hydroxy and/or halogen, if not mentioned otherwise.

For example, substituents in the optionally substituted alkyl group are one or more substitutents independently selected from the group of substituents mentioned in the last paragraph.

Alkenyl—as a group per se se and as a structural element of other groups and compounds, such as alkenoylamino—is preferably C₂–C₁₆-, more preferably C₂–C₈-, especially C₃–C₈-, very especially C₃–C₇-, for example C₃–C₄-alkenyl, and is either straight-chained, for example vinyl, 1-methylvinyl, allyl, 1-butenyl or 2-hexenyl, or branched, for example isopropenyl. Preferably (for reasons of chemical stability) the C-atoms in alkenyl that are bonded to a heteroatom (e.g. N, O or S) do not carry the double bond.

Alkynyl—as a group per se and as a structural element of other groups and compounds, such as alkynoylamino—is preferably C₂–C₁₆-, more preferably C₂–C₈-, especially C₃–C₈-, very especially C₃–C₇-, for example C₃–C₄-alkenyl, and is either straight-chained, for example propargyl, 2-butynyl or 5-hexynyl, or branched, for example 2-ethynylpropyl or 2-propargyl-isopropyl. Preferably (for reasons of chemical stability) the C-atoms in alkynyl that are bonded to a heteroatom (e.g. N, O or S) do not carry the triple bond.

One—to threefold substituted hydrazino preferably carries one to three substituents independently selected from the group consisting of alkyl, haloalkyl, such as trifluoromethyl, hydroxyalkyl, such as 2-hydroxyethyl, hydroxymethyl or 1-hydroxymethyl-n-propyl, alkoxyalkyl, such as 2-methoxyethyl, ethoxymethyl or 1-methoxymethyl-n-propyl, and acyl. Optionally substitued alkyl is preferably as defined above.

Acyl is preferably C₁–C₁₆alkanoyl, more preferably lower alkanoyl, and is linear or branched. Lower alkanoyl is preferably formyl, acetyl or in a broader sense of the invention propionyl or butyryl.

Substitutents in the optionally substituted acyl group are preferably one or more substituents independently selected from halogen (more preferably fluorine), hydroxy or alkoxy (more preferably methoxy or ethoxy), e.g. in trifluoroacetyl or pentafluoropropionyl.

Substituted hydrazinyl is preferably hydroxy-lower alkyl-hydrazino; 2-hydroxyethyl is an especially preferred substituent of the hydrazino group.

Cyclohexyl-amino substituted by amino is preferably 2- or 4-amino-cyclohexyl-amino.

Piperazinyl is preferably 1-piperazinyl. As substituted piperazinyl, piperazinyl substituted by amino-lower alkyl is preferred, especially 4-(2-amino-ethyl)-piperazin-1-yl.

Morpholinyl is preferably 4-morpholinyl (=morpholino). Lower alkylamino R₆ substituted by morpholinyl is preferably 2-morpholin-4-yl-ethylamino. Substituted morpholinyl is preferably 3-alkyl- or 3,5-dialkylmorpholino, more preferably 3-methyl- or 3,5-dimethylmorpholino.

Formyl-piperazinyl is preferably 4-formyl-piperazinyl.

Lower alkyl that is substituted by unsubstituted mono- or di-(lower alkyl)-amino in mono- or di-(lower alkyl)-amino R₆ with one or (if two are present) both moieties substituted is preferably lower alkyl that is substituted by N-mono- or N,N-di-(lower alkyl)amino, preferably dimethylamino; preferred is lower alkylamino that is substituted by N-mono- or N,N-di-(lower alkyl)amino, most preferably 3-(dimethylamino)-1-methyl-n-propylamino.

Lower alkyl substituted by amino in mono- or di-(lower alkyl)-amino R₆ with one or (if two are present) both lower alkyl moieties substituted is preferably lower alkyl substituted by one or two amino groups; preferred is mono-lower alkyl that is substituted by one or more, especially 1 or 2, amino groups, especially 2-amino-ethylamino or 3-amino-n-propylamino.

(Lower alkoxy)-lower alkoxy as substituent of a substituted lower alkyl moiety of mono- or di-(lower alkyl)-amino is preferably (methoxy)-methoxy.

A preferred di-(lower alkyl)amino R₆ wherein the lower alkyl moieties are substituted by (lower alkoxy)-lower alkoxy and lower alkoxy is N-(methoxymethyl)-N-{2-[(methoxy)-methoxy]-1-methyl-ethyl}-amino.

Hydroxy-lower alkylamino is preferably hydroxy-lower alkyl that carries one or more, especially one or two, hydroxy groups, more preferably 2-hydroxy-ethylamino. Lower alkylamino substituted by hydroxy-lower alkylamino is preferably 3-(2-hydroxy-ethyl-amino)-prop-1-yl-amino

Oxo is not bonded to a carbon atom that is bound to a heteroatom, such as nitrogen, sulfur or oxygen, in order to avoid overlap with acyl substituents.

Lower alkylamino-carbonylamino is preferably methylamino-carbonyl-amino.

Di-lower alkylamino is preferably dimethylamino.

Alkoximino is preferably C₁–C₁₆-, more preferably C₁–C₈-, most preferably lower alkoximino.

Optionally substituted hydrazono is preferably hydrazono or hydrazono substituted with one of the substituents defined above for “optionally substituted”. Hydrazono or N-lower alkylhydrazono is preferred.

Lower alkyl substituted by hydroxy in mono- or di-(lower alkyl)-amino R₆ with one or (if two are present) both lower alkyl moieties substituted is preferably lower alkylamino that carries one or more hydroxy substituents, especially 1 or 2 hydroxy substituents, preferred is mono-lower alkyl-amino that is substituted by one or two hydroxy groups, especially 2- or 3-hydroxy-n-propylamino, 1,1-dimethyl-3-hydroxy-n-propylamino, 1-n-propyl-2-hydroxy-ethylamino, 1,1-dimethyl-2-hydroxy-ethylamino, 1-ethyl-2-hydroxy-ethylamino, 2-hydroxy-1-(hydroxy-methyl)-ethylamino, 2-hydroxy-1-methyl-ethylamino or 2-hydroxy-1-(sec-butyl)-ethylamino.

Lower alkyl substituted by lower alkoxy in mono- or di-lower alkylamino R₆ with one or (if two are present) both lower alkyl moieties substituted is preferably lower alkyl that is substituted by one or more, especially 1 or 2, lower alkoxy groups; preferred is mono-lower alkylamino R₆ wherein the lower alkyl moieties are substituted by lower alkoxy, especially 2-methoxy-ethylamino, 1-ethyl-2-methoxy-ethylamino, 2-methoxy-1-methyl-ethylamino, 2-methoxy-2-methyl-ethylamino, 1,1-dimethyl-2-methoxy-ethylamino, 1,1-dimethyl-3-methoxy-n-propylamino or 3-methoxy-propylamino.

Lower alkyl substituted by carboxy in mono- or di-lower alkylamino R₆ with one or (if two are present) both lower alkyl moieties substituted is preferably carboxymethyl.

Lower alkoxycarbonyl-amino is preferably ethoxycarbonyl-amino. Preferred is mono-lower alkylamino R₆ that is substituted by lower alkoxycarbonylamino, especially 3-[N-(ethoxycarbonyl)-amino]-n-propylamino.

Lower alkyl substituted by cyano, guanidyl, lower alkanoyl-amino, lower alkylaminocarbonylamino, amidino, di-lower alkylamino-cyclohexyl, lower alkoxycarbonyl, carbamoyl, N-hydroxy-carbamoyl, piperazinyl, lower alkanoyl-piperazinyl, formylpiperazinyl, tetrahydro-4H-pyranyl-4-amino, pyrrolidine-3-amino, 2- or 3-tetrahydrofurylamino, optionally substituted heteroaryl or optionally substituted heteroaryloxy is preferably di- or tri-methyleneamino substituted by those substituents, the substituents preferably being in the ω-position. The same holds true for other substitutents of lower alkyl in substituted mono- or di-lower alkylamino that are not defined in more detail.

Heteroaryl (in the term heteroaryl and heteroaryloxy) is a cyclic aromatic group with one or two rings with a total of 5 to 12 ring members, 1 to 3 members of which are hetero atoms, preferably selected from the group consisting of oxygen, sulphur and nitrogen. 1 to 2 benzene rings may be condensed onto the heterocycle, whereby the binding to the residual molecule takes place either via the hetero or the benzene moiety. Preferably, heteroaryl is benzimidazolyl, benzisoxazolyl, benzisothiazolyl, benzocoumarinyl, benzofuryl, benzothiadiazolyl, benzothiazolyl, benzothienyl, benzoxazolyl, benzoxdiazolyl, quinazolinyl, quinolyl, quinoxalinyl, carbazolyl, dihydrobenzofuryl, furyl (especially 2- or 3-furyl), imidazolyl (especially 1-imidazolyl), indazolyl, indolyl, isoquinolinyl, isothiazolyl, isoxazolyl, methylenedioxyphenyl, ethylenedioxyphenyl, naphthyridinyl, oxazolyl, phenanthridinyl, phthalazinyl, pteridinyl, purinyl, pyrazinyl, pyrazolyl, pyridazinyl, pyrazolo[3,4-b]pyridyl, pyridyl (especially 2-, 3- or 4-pyridyl), pyrimidyl, pyrrolyl, tetrazolyl (especially tetrazol-1-yl), oxadiazolyl, thiadiazolyl, thiazolyl (especially 2-, 4- or 5-thiazolyl), thienyl (especially 2- or 3-thienyl), triazinyl (especially 1,3,5-triazinyl) and triazolyl (especially 1,2,4-triazol-1-yl). Furyl, pyridyl, imidazolyl and triazolyl are preferred.

The heteroaryl and heteroryloxy moiety may be substituted by one or more, preferably one to three identical or different substitutents selected from the group comprising halogen, C₁–C₆-alkyl, C₃–C₆-cycloalkyl, halogen-C₁–C₆-alkyl, hydroxy, C₁–C₆-alkoxy, halogen-C₁–C₆-alkoxy, C₁–C₆-alkylthio, halogen-C₁–C₆-alkylthio, C₁–C₆-alkyll, halogen-C₁–C₆-alkyll, C₁–C₆-alkylsulfinyl, halogen-C₁–C₆-alkylsulfinyl, C₁–C₆-alkylsulfonyl, halogen-C₁–C₆-alkylsulfonyl, C₁–C₆-alkyl-carbonyl, halogen-C₁–C₆-alkylcarbonyl, carboxyl, C₁–C₆-alkoxycarbonyl, halogen-C₁–C₆-alkoxycarbonyl, aminocarbonyl, C₁–C₆-alkylaminocarbonyl, di-(C₁–C₆-alkyl)-aminocarbonyl, whereby the alkyl groups may be identical or different, amino, C₁–C₆-alkylamino, di-(C₁–C₆-alkyl)-amino, NO₂, CN, C₂–C₆-alkenyl or C₂–C₆-alkynyl.

Alkanoylamino is preferably C₁–C₁₆alkanoylamino, more preferably C₁–C₆-alkanoylamino, most preferably lower alkanoylamino, especially formylamino, acetylamino, propionylamino, butanoylamino and pentanoylamino. Preferred substituents of the alkanoyl group are one or more, especially 1 to five, substituents independently selected from the group consisting of fluorine, hydroxy and methoxy. Especially preferred are trifluoroacetylamino and 2-hydroxy-propionylamino.

A five- to seven-membered ring with 0, 1 or 2 ring nitrogen atoms formed from R₇ and R₈ together with the binding carbon atom preferably has 2 ring nitrogen atoms that are immediately adjacent (=bound) to the binding carbon atom, for example forming an imidazolidin-2-ylidene, tetrahydropyrimidin-2-ylidene or hexahydro-1,3-diazepin-2-ylidene moiety, and is optionally substituted, especially unsubstituted or substituted by one to three lower alkyl moieties, especially methyl, etyhl, propyl or isopropyl, which may be bound to carbon or nitrogen ring atoms.

As substituents R₆, those mentioned specifically in Table A given below and/or in the Examples are especially preferred and can be combined with the other moieties R₁ to R₅ in formula I.

Within the scope of this text, the term “lower” denotes radicals having up to and including 7, preferably up to and including 4, carbon atoms. Unless otherwise indicated in the context concerned, lower alkyl is preferably methyl or ethyl. In the case of alkenyl or alkinyl, “lower” means C₂–C₇-, more preferably C₃–C₇-, such as C₃–C₄-alkenyl or -alkinyl, and the double- or triple bond preferably does not start from a heteroatom, especially S, N or O, most especially one carrying a hydrogen, such as NH, OH or SH.

The compounds of formula I can form acid addition salts, for example with inorganic acids, such as hydrochloric acid, sulfuric acid or a phosphoric acid, or with suitable organic carboxylic or sulfonic acids, for example aliphatic mono- or di-carboxylic acids, such as trifluoroacetic acid, acetic acid, propionic acid, glycolic acid, succinic acid, maleic acid, fumaric acid, hydroxymaleic acid, malic acid, tartaric acid, citric acid, oxalic acid or amino acids, such as arginine or lysine, aromatic carboxylic acids, such as benzoic acid, 2-phenoxy-benzoic acid, 2-acetoxy-benzoic acid, salicylic acid, 4-aminosalicylic acid, aromatic-aliphatic carboxylic acids, such as mandelic acid or cinnamic acid, heteroaromatic carboxylic acids, such as nicotinic acid or isonicotinic acid, aliphatic sulfonic acids, such as methane-, ethane- or 2-hydroxy-ethane-sulfonic acid, or aromatic sulfonic acids, for example benzene-, p-toluene- or naphthalene-2-sulfonic acid. Mono, di- or, if other basic groups, such as amino or guanidyl groups, are present in the radical R₆, poly-acid addition salts can be formed.

Compounds of formula I having acidic groups, for example a free carboxy group in the radical R₆, can form metal or ammonium salts, such as alkali metal or alkaline earth metal salts, for example sodium, potassium, magnesium or calcium salts, or ammonium salts with ammonia or suitable organic amines, such as tertiary monoamines, for example triethylamine or tri(2-hydroxyethyl)amine, or heterocyclic bases, for example N-ethyl-piperidine or N,N′-dimethyl-piperazine.

Compounds of formula I that possess both acidic and basic groups can form internal salts.

The pyridine-N-oxides of formula I (n=1) can form acid addition salts with strong acids, such as hydrochloric acid, nitric acid, phosphoric acid or sulfonic acids, such as benzene-sulfonic acid. The compounds of formula I with n=1 are new and thus form an especially preferred embodiment of the invention, as their use and process of manufacture.

Formula I is meant to include all the possible isomeric forms, as well as mixtures, e.g. racemic mixtures, and any [E/Z] mixtures.

In view of the close relationship between the compounds of formula I in free form and in the form of their salts, including also salts that can be used as intermediates, for example in the purification of the compounds of formula I or in order to identify those compounds, herein-before and hereinafter any reference to the (free) compounds is to be understood as including also the corresponding salts, where appropriate and expedient.

Where hereinbefore and hereinafter reference is made that “compounds can be used according to the invention” or a “method for applying a compound of formula I” or to “compounds to be used according to the invention, this refers to the fact that the invention relates to any one or more of

-   (i) the use of a compound of the formula I, or a salt thereof, for     protection of a plant against attack by a phytopathogenic organism     or the treatment of a plant infested by a phytopathogenic organism,     said use comprising the administration of a compound of the formula     I or a salt thereof, or a composition comprising said compound or     salt and a carrier material acceptable for agricultural purposes, to     any one or more selected from the group consisting of a plant, a     part of a plant, seeds and the locus of a plant; -   (ii) a method of protecting a plant against attack by a     phytopathogenic organism and/or the treatment of a plant infested by     a phytopathogenic organism, said method comprising administering a     compound of the formula I or a salt thereof, or a composition     comprising said compound or salt and a carrier material acceptable     for agricultural purposes, to any one or more selected from the     group consisting of a plant, a part of a plant, seeds and the locus     of a plant, preferably if in need of such treatment; -   (iii) a process for protecting a plant against attack by a     phytopathogenic organism and/or the treatment of a plant infested by     a phytopathogenic organism, said process comprising administering a     compound of the formula I or a salt thereof, or a composition     comprising said compound or salt and a carrier material acceptable     for agricultural purposes, to any one or more selected from the     group consisting of a plant, a part of a plant, seeds and the locus     of a plant; and/or -   (iv) a composition (useful) for protecting a plant against attack by     a phytopathogenic organisms and/or the treatment of a plant infested     by a phytopathogenic organism, said composition comprising a     compound of the formula I or a salt thereof and a carrier material     acceptable for agricultural purposes. -   Any of these uses, methods, processes or compositions is meant as     preferred part of the invention where the respective reference given     above in citation marks is/are made.

In the preferred or more specific embodiments of the invention given above and below, the definitions given above can be used instead of more general terms, thus leading to preferred embodiments of the invention.

The compounds of formula I may be used preventatively and/or curatively in the agrarian sector and related fields as active ingredients for controlling plant pests. The active ingredients of formula I according to the invention are notable for their good activity even at low concentrations, for their good plant tolerance and for their environmentally friendly nature. They have very advantageous, especially systemic, properties and may be used to protect a plurality of cultivated plants. Using the active ingredients of formula I on plants or plant parts (fruit, flowers, leaves, stems, tubers, roots) of various crops, the pests appearing can be controlled or destroyed, whereby the parts of plants which grow later also remain protected, e.g. from phytopathogenic micro-organisms.

The compounds of formula I may additionally be used as a dressing to treat seeds (fruits, tubers, corms) and plant cuttings to protect against fungal infections and against phytopathogenic fungi occurring in the soil.

The compounds of formula I are effective for example against the following classes of related phytopathogenic fungi: Fungi imperfecti (e.g. Botrytis, Pyricularia, Helminthosporium, Fusarium, Septoria, Cercospora and Altemaria); Basidiomycetes (e.g. Rhizoctonia, Hemileia, Puccinia); Ascomycetes (e.g. Venturia and Erysiphe, Podosphaera, Monilinia, Uncinula) and Oomycetes (e.g. Phytophthora, Pythium, Plasmopara).

Target crops for the plant-protecting usage in terms of the invention are for example the following plant cultivars: cereals (wheat, barley, rye, oats, rice, maize, sorghum and related species); beet (sugar beet and fodder beet); pome, stone and berry fruit (apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries and blackberries); legumes (beans, lentils, peas, soya); oil crops (rape, mustard, poppy, olives, sunflowers, coconut, castor oil, cocoa, peanut); cucumber plants (squashes, cucumber, melons); citrus fruits (oranges, lemons, grapefruits, mandarines); vegetables (spinach, lettuce, asparagus, cabbage varieties, carrots, onions, tomatoes, potatoes, paprika); laurels (avocado, cinnamonium, camphor) and plants such as tobacco, nuts, coffee, aubergines, sugar cane, tea, pepper, vines, hops, bananas and natural rubber plants, as well as ornamental plants.

Further areas of application for the active ingredients according to the invention are the protection of stores and material, where the storage matter is protected against putrescence and mould.

The compounds of formula I are used in unchanged form or preferably together with customary excipients in formulation techniques. To this end, they are conveniently processed in known manner e.g. into emulsion concentrates, coatable pastes, directly sprayable or diluable solutions, diluted emulsions, wettable powders, soluble powders, dusts or granules, e.g. by encapsulation into for example polymeric materials. As with the type of medium, the application processes, such as spraying, atomizing, dusting, scattering, coating or pouring are similarly chosen according to the desired aims and the prevailing conditions.

Suitable substrates and additives may be solid or liquid and are useful substances in formulation techniques, e.g. natural or regenerated mineral substances, dissolving aids, dispersants, wetting agents, tackifiers, thickeners, binding agents or fertilizers.

The compounds of formula I may be mixed with further active ingredients, e.g. fertilizers, ingredients providing trace elements or other plant protection compositions, especially further fungicides. In doing so, unexpected synergistic effects may occur.

Preferred additions to the mixture are:

-   Azoles, such as azaconazole, bitertanol, bromuconazole,     cyproconazole, difenoconazole, diniconazole, epoxiconazole,     fenbuconazole, fluquinconazole, flusilazole, flutriafol,     hexaconazole, imazalil, imibenconazole, ipconazole, metconazole,     myclobutanil, pefurazoate, penconazole, pyrifenox, prochloraz,     propiconazole, tebuconazole, tetraconazole, triadimefon,     triadimenol, triflumizole, triticonazole; -   pyrimidinyl carbinoles, such as ancymidol, fenarimol, nuarimol; -   2-amino-pyrimidines, such as bupirimate, dimethirimol, ethirimol; -   morpholines, such as dodemorph, fenpropidine, fenpropimorph,     spiroxamin, tridemorph; -   anilinopyrimidines, such as cyprodinil, mepanipyrim, pyrimethanil; -   pyrroles, such as fenpiclonil, fludioxonil; -   phenylamides, such as benalaxyl, furalaxyl, metalaxyl, r-metalaxyl,     ofurace, oxadixyl; -   benzimidazoles, such as benomyl, carbendazim, debacarb,     fuberidazole, thiabendazole; -   dicarboximides, such as chlozolinate, dichlozoline, iprodione,     myclozoline, procymidone, vinclozoline; -   carboxamides, such as carboxin, fenfuram, flutolanil, mepronil,     oxycarboxin, thifluzamide; -   guanidines, such as guazatine, dodine, iminoctadine; -   strobilurines, such as azoxystrobin, kresoxim-methyl,     metominostrobin, SSF-129, trifloxystrobin; -   dithiocarbamates, such as ferbam, mancozeb, maneb, metiram,     propineb, thiram, zineb, ziram; -   N-halomethylthio, such as captafol, captan, dichlofluanid,     fluoromides, folpet, tolyfluanid; -   Cu compounds, such as Bordeaux mixture, copper hydroxide, copper     oxychloride, copper sulfate, cuprous oxide, mancopper, oxine-copper; -   nitrophenol-derivatives, such as dinocap, nitrothal-isopropyl; -   organo-p-derivatives, such as edifenphos, iprobenphos,     isoprothiolane, phosdiphen, pyrazophos, tolclofos-methyl;     Various others, such as acibenzolar-S-methyl, anilazine,     blasticidin-S, chinomethionate, chloroneb, chlorothalonil,     cymoxanil, dichlone, diclomezine, dicloran, diethofencarb,     dimethomorph, dithianon, etridiazole, famoxadone, fenamidone,     fentin, ferimzone, fluazinam, flusulfamide, fenhexamid,     fosetyl-aluminium, hymexazol, iprovalicarb, IKF-916, kasugamycin,     methasulfocarb, pencycuron, phthalide, polyoxins, probenazole,     propamocarb, pyroquilon, quinoxyfen, quintozene, sulfur, triazoxide,     tricyclazole, triforine, validamycin.

One preferred method of application of an active ingredient of formula I or of an agrochemical composition containing at least one of these active ingredients is foliar application. The frequency and amount of application depend on the severity of the attack by the pathogen in question. However, the active ingredients I may also reach the plants through the root system via the soil (systemic action) by drenching the locus of the plant with a liquid preparation or by incorporating the substances into the soil in solid form, e.g. in the form of granules (soil application). In rice cultivations, these granules may be dispensed over the flooded paddy field. The compounds I may however also be applied to seed grain to treat seed material (coating), whereby the grains or tubers are either drenched in a liquid preparation of the active ingredient or coated with a solid preparation.

The compositions are produced in known manner, e.g. by intimately mixing and/or grinding the active ingredient with extenders such as solvents, solid carriers and optionally surfactants.

The agrochemical compositions normally contain 0.1 to 99 percent by weight, especially 0.1 to 95 percent by weight, of active ingredient of formula I, 99.9 to 1 percent by weight, especially 99.8 to 5 percent by weight, of a solid or liquid additive and 0 to 25 percent by weight, especially 0.1 to 25 percent by weight, of a surfactant.

Favourable application rates are in general 1 g to 2 kg of active substance (AS) per hectare (ha), preferably 10 g to 1 kg AS/ha, especially 20 g to 600 g AS/ha. For usage as a seed dressing, it is advantageous to use dosages of 10 mg to 1 g active substance per kg of seed grain.

While concentrated compositions are preferred for commercial usage, the end user normally uses diluted compositions.

The compositions may also contain further additives, such as stabilizers, anti-foaming agents, viscosity regulators, binding agents or tackifiers, as well as fertilizers or other active ingredients to achieve special effects.

Formulations may be prepared analogously to those described for example in WO 97/33890.

In the following, examples for test systems that demonstrate the efficiency of the compounds of the formula I (designated as “active ingredient” or “test compounds”) in plant protection are provided:

BIOLOGICAL ASSAYS

Assay B-1: Effect against Puccinia graminis on Wheat (Brownrust on Wheat)

a) Residual Protective Activity

1 week old wheat plants cv. Arina are treated with the formulated testcompound (0.02% active substance) in a spray chamber. Two days after application wheat plants are inoculated by spraying a spore suspension (1×10⁵ uredospores/ml) on the test plants. After an incubation period of 1 day at 20° C. and 95% relative atmospheric humidity (r. h.) plants are kept for 9 days at 20° C. and 60% r.h.in a greenhouse. The disease incidence is assessed 10 days after inoculation.

b) Systemic Activity

An aqueous spray liquor prepared from the formulated testcompound (0.002% active substance, based on the volume of soil) is poured onto wheat plants 5 days after sowing. Care is taken that the spray liquor does not come into contact with the above-ground parts of the plant. 48 hours later, the plants are inoculated with a spore suspension of the fungus. After an incubation period of 48 hours (95 to 100% r.h. at 20° C.), the plants are placed in a greenhouse at 20° C. 12 days after infection, the disease incidence is evaluated.

Assay B-2: Effect Against Phytophthora infestans on Tomatoes (Late Blight on Potato)

a) Residual Protective Activity

3 week old tomato plants cv. Roter Gnom are treated with the formulated testcompound (0.02% active substance) in a spray chamber. Two day after application the plants are inoculated by spraying a sporangia suspension (2×10⁴ sporangia/ml) on the test plants. After an incubation period of 4 days at 18° C. and 95% r. h. in a growth chamber the disease incidence is assessed.

b) Systemic Activity

An aqueous suspension prepared from the formulated test compound (0.002% active substance, based on the volume of soil) is poured onto tomato plants which have been cultivated for three weeks. Care is taken that the spray liquor does not come into contact with the above-ground parts of the plant. 48 hours later, the plants are inoculated with a sporangia suspension of the fungus. Evaluation of the disease incidence takes place 5 days after infection, during which period conditions of 90 to 100% r.h. and 20° C. are maintained.

Assay B-3: Effect Against Phytophthora infestans/Potato (Late Blight on Potato)

5 week old potato plants cv. Bintje are treated with the formulated testcompound (0.02% active substance) in a spray chamber. Two days after application the plants are inoculated by spraying a sporangia suspension (1.4×10⁵ sporangia/ml) on the test plants. After an incubation period of 4 days at 18° C. and 95% r. h. in a growth chamber the disease incidence is assessed.

Assay B-4: Effect Against Plasmopara viticola on Grapevine (Grape Downy Mildew)

5 week old grape seedlings cv. Gutedel are treated with the formulated testcompound (0.02% active substance) in a spray chamber. One day after application grape plants are inoculated by spraying a sporangia suspension (4×10⁴ sporangia/ml) on the lower leaf side of the test plants. After an incubation period of 6 days at 22° C. and 95% r. h. in a greenhouse the disease incidence is assessed.

Assay B-5: Residual Protective Activity Against Venturia inaegualis on Apples (Scab on Apple)

4 week old apple seedlings cv. McIntosh are treated with the formulated testcompound (0.02% active substance) in a spray chamber. One day after application apple plants are inoculated by spraying a spore suspension (4×10⁵ conidia/ml) on the test plants. After an incubation period of 4 days at 21° C. and 95% r. h. the plants are placed for 4 days at 21° C. and 60% r. h. in a greenhouse. After another 4 day incubation period at 21° C. and 95% r. h. the disease incidence is assessed.

Assay B-6: Effect Against Erysiphe graminis on Barley (Powdery Mildew on Barley)

a) Residual Protective Activity

Barley plants of approximately 8 cm height are sprayed to drip point with an aqueous spray liquor prepared from wettable powder of the active ingredient (0.02% active substance), and dusted 3 to 4 hours later with conidia of the fungus. The infected plants are placed in a greenhouse at 22°. 12 days after infection, the fungal attack is evaluated.

b) Systemic Activity

An aqueous spray liquor prepared from the formulated test compound (0.002% active substance, based on the volume of soil) is poured onto barley plants of approximately 8 cm height. Care is taken that the spray liquor does not come into contact with the abouve-ground parts of the plant. 48 hours later, the plants are dusted with conidia of the fungus. The infected plants are placed in a greenhouse at 22° C. 12 days after infection, the disease incidence is evaluated.

Assay B-7: Botrytis cinerea/Grape (Botrytis on Grapes)

5 week old grape seedlings cv. Gutedel are treated with the formulated testcompound (0.02% active substance) in a spray chamber. Two days after application grape plants are inoculated by spraying a spore suspension (1×10⁶ conidia/ml) on the test plants. After an incubation period of 4 days at 21° C. and 95% r. h. in a greenhouse the disease incidence is assessed.

Assay B-8: Effect Against Botrytis cinerea/Tomato (Botrytis on Tomatoes)

4 week old tomato plants cv. Roter Gnom are treated with the formulated testcompound 0.02% active substance) in a spray chamber. Two days after application tomato plants are inoculated by spraying a spore suspension (1×10⁵ conidia/ml) on the test plants. After an incubation period of 4 days at 20° C. and 95% r. h. in a greenhouse the disease incidence is assessed.

Assay B-9: Effect Against Pyricularia oryzae/Rice (Rice Blast)

3 week old rice plants cv. Sasanishiki are treated with the formulated testcompound (0.02% active substance) in a spray chamber. Two days after application rice plants are inoculated by spraying a spore suspension (1×10⁵ conidia/ml) on the test plants. After an incubation period of 6 days at 25° C. and 95% r. h. the disease incidence is assessed.

Assay B-10: Effect Against Pyrenophora teres (Helminthosporium)/Barley (Net Blotch on Barley)

1 week old barley plants cv. Regina are treated with a formulated testcompound (0.02% active substance) in a spray chamber. Two days after application barley plants are inoculated by spraying a spore suspension (3×10⁴ conidia/ml) on the test plants. After an incubation period of 2 days at 20° C. and 95% r.h. plants are kept for 2 days at 20° C. and 60% r.h. in a greenhouse. The disease incidence is assessed 4 days after inoculation.

Assay B-11: Effect Against Fusarium culmorum/Wheat (Fusarium Head Blight on Wheat)

A conidia suspension of F. culmorum (7×10⁵ conidia/ml) is mixed with the formulated test compound (0.002% active substance). The mixture is applied into a pouch which has been equipped before with a filter paper. After the application wheat seeds (cv. Orestis) are sown into the upper fault of the filter paper. The prepared pouches are then incubated for 11 days at approx. 10–18° C. and a relative humidity of 100% with a light period of 14 hours. The evaluation is made by assessing the degree of disease occurrence in the form of brown lesions on the roots.

Assay B-12: Effect Against Septoria nodorum/Wheat (Septoria Leaf Spot on Wheat)

1 week old wheat plants cv. Arina are treated with a formulated test compound (0.02% active substance) in a spray chamber. One day after application wheat plants are inoculated by spraying a spore suspension (5×10⁵ conidia/ml) on the test plants. After an incubation period of 1 day at 20° C. and 95% r.h. plants are kept for 10 days at 20° C. and 60% r.h. in a greenhouse. The disease incidence is assessed 11 days after inoculation.

Preferred among the compounds to be used according to the invention is a compound of the following tables.

TABLE 1 Compounds of the general formula I.1, in which R₁ is fluorine, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A. (I)

Table 2

Compounds of the general formula I.1, in which R₁ is chlorine, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 3

Compounds of the general formula I.1, in which R₁ is bromine, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 4

Compounds of the general formula I.1, in which R₁ is trifluoromethyl, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 5

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 6

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 7

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 8

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ and R₃ are hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 9

Compounds of the general formula I.1, in which R₁ is fluorine, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 10

Compounds of the general formula I.1, in which R₁ is chlorine, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 11

Compounds of the general formula I.1, in which R₁ is bromine, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 12

Compounds of the general formula I.1, in which R₁ is tritluoromethoxy, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 13

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 14

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 15

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ is methyl, R₃ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 16

Compounds of the general formula I.1, in which R₁ and R₃ are fluorine, R₂ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 17

Compounds of the general formula I.1, in which R₁ is chlorine, R₂ is hydrogen, R₃ is fluorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 18

Compounds of the general formula I.1, in which R₁ is bromine, R₂ is hydrogen, R₃ is fluorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 19

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ is hydrogen, R₃ is fluorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 20

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ is hydrogen, R₃ is fluorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 21

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ is hydrogen, R₃ is fluorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 22

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ is hydrogen, R₃ is fluorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 23

Compounds of the general formula I.1, in which R₁ and R₃ are chlorine, R₂ is hydrogen, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 24

Compounds of the general formula I.1, in which R₁ is fluorine, R₂ is hydrogen, R₃ is chlorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 25

Compounds of the general formula I.1, in which R₁ is bromine, R₂ is hydrogen, R₃ is chlorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 26

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ is hydrogen, R₃ is chlorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 27

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ is hydrogen, R₃ is chlorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 28

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ is hydrogen, R₃ is chlorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 29

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ is hydrogen, R₃ is chlorine, n is 0, and R₆ corresponds in each case to one of the lines of Table A.

Table 30

Compounds of the general formula I.1, in which R₁ is fluorine, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 31

Compounds of the general formula I.1, in which R₁ is chlorine, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 32

Compounds of the general formula I.1, in which R₁ is bromine, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 33

Compounds of the general formula I.1, in which R₁ is trifluoromethyl, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 34

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 35

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 36

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 37

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ and R₃ are hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 38

Compounds of the general formula I.1, in which R₁ is fluorine, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 39

Compounds of the general formula I.1, in which R₁ is chlorine, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 40

Compounds of the general formula I.1, in which R₁ is bromine, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 41

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 42

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 43

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 44

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ is methyl, R₃ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 45

Compounds of the general formula I.1, in which R₁ and R₃ are fluorine, R₂ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 46

Compounds of the general formula I.1, in which R₁ is chlorine, R₂ is hydrogen, R₃ is fluorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 47

Compounds of the general formula I.1, in which R₁ is bromine, R₂ is hydrogen, R₃ is fluorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 48

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ is hydrogen, R₃ is fluorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 49

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ is hydrogen, R₃ is fluorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 50

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ is hydrogen, R₃ is fluorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 51

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ is hydrogen, R₃ is fluorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 52

Compounds of the general formula I.1, in which R₁ and R₃ are chlorine, R₂ is hydrogen, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 53

Compounds of the general formula I.1, in which R₁ is fluorine, R₂ is hydrogen, R₃ is chlorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 54

Compounds of the general formula I.1, in which R₁ is bromine, R₂ is hydrogen, R₃ is chlorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 55

Compounds of the general formula I.1, in which R₁ is trifluoromethoxy, R₂ is hydrogen, R₃ is chlorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 56

Compounds of the general formula I.1, in which R₁ is chlorodifluoromethoxy, R₂ is hydrogen, R₃ is chlorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 57

Compounds of the general formula I.1, in which R₁ is 2,2,2-trifluoroethoxy, R₂ is hydrogen, R₃ is chlorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

Table 58

Compounds of the general formula I.1, in which R₁ is 1,1,2,2-tetrafluoroethoxy, R₂ is hydrogen, R₃ is chlorine, n is 1, and R₆ corresponds in each case to one of the lines of Table A.

TABLE A No. R6 1. NHNH₂ 2. NHNHCH₃ 3. NHNHCH₂CH₃ 4. NHNH(CH₂)₂CH₃ 5. NHNH(CH₂)₃CH₃ 6. NHNHCH(CH₃)₂ 7. NHNHC(CH₃)₃ 8. NHN(CH₃)₂ 9. NHN(CH₂CH₃)₂ 10. NHN[(CH₂)₂CH₃]₂ 11. NHN[(CH₂)₃CH₃]₂ 12. NHN[CH(CH₃)₂]₂ 13. NHN(CH₃)C(CH₃)₃ 14. NHN(CH₃)CH₂CH₃ 15. N(CH₃)NH₂ 16. N(CH₃)NHCH₃ 17. N(CH₃)NHCH₂CH₃ 18. N(CH₃)NH(CH₂)₂CH₃ 19. N(CH₃)NH(CH₂)₃CH₃ 20. N(CH₃)NHCH(CH₃)₂ 21. N(CH₃)NHC(CH₃)₃ 22. N(CH₃)N(CH₃)₂ 23. N(CH₃)N(CH₂CH₃)₂ 24. N(CH₃)N[(CH₂)₂CH₃]₂ 25. N(CH₃)N[(CH₂)₃CH₃]₂ 26. N(CH₃)N[CH(CH₃)₂]₂ 27. N(CH₃)N(CH₃)C(CH₃)₃ 28. N(CH₃)N(CH₃)CH₂CH₃ 29. N(CH₂CH₃)NH₂ 30. N(CH₂CH₃)NHCH₃ 31. N(CH₂CH₃)NHCH₂CH₃ 32. N(CH₂CH₃)NH(CH₂)₂CH₃ 33. N(CH₂CH₃)NH(CH₂)₃CH3 34. N(CH₂CH₃)NHCH(CH₃)₂ 35. N(CH₂CH₃)NHC(CH₃)₃ 36. N(CH₂CH₃)N(CH₃)₂ 37. N(CH₂CH₃)N(CH₂CH₃)₂ 38. N(CH₂CH₃)N[(CH₂)₂CH₃]₂ 39. N(CH₂CH₃)N[(CH₂)₃CH₃]₂ 40. N(CH₂CH₃)N[CH(CH₃)₂]₂ 41. N(CH₂CH₃)N(CH₃)CH₂CH₃ 42. N(CH₂CF₃)NH₂ 43. N(CH₂CF₃)NHCH₃ 44. N(CH₂CF₃)NHCH₂CH₃ 45. N(CH₂CF₃)NH(CH₂)₂CH₃ 46. N(CH₂CF₃)NH(CH₂)₃CH₃ 47. N(CH₂CF₃)NHCH(CH₃)₂ 48. N(CH₂CF₃)NHC(CH₃)₃ 49. N(CH₂CF₃)N(CH₃)₂ 50. N(CH₂CF₃)N(CH₂CH₃)₂ 51. N(CH₂CF₃)N[(CH₂)₂CH₃]₂ 52. N(CH₂CF₃)N[(CH₂)₃CH₃]₂ 53. N(CH₂CF₃)N[CH(CH₃)₂]₂ 54. N(CH₂CF₃)N(CH₃)CH₂CH₃ 55. NHNHCH₂CF₃ 56. NHN(CH₃)CH₂CF₃ 57. NHN(CH₂CH₃)CH₂CF₃ 58. NHN(CH₂CF₃)₂ 59. N(CH₃)NHCH₂CF₃ 60. N(CH₃)N(CH₃)CH₂CF₃ 61. N(CH₃)N(CH₂CH₃)CH₂CF₃ 62. N(CH₃)N(CH₂CF₃)₂ 63. N(CH₂CH₃)NHCH₂CF₃ 64. N(CH₂CH₃)N(CH₃)CH₂CF₃ 65. N(CH₂CH₃)N(CH₂CH₃)CH₂CF₃ 66. N(CH₂CH₃)N(CH₂CF₃)₂ 67. N(CH₂CF₃)NHCH₂CF₃ 68. N(CH₂CF₃)N(CH₂CF₃)₂ 69. N(CH₂CH₂OH)NH₂ 70. N(CH₂CH₂OH)NHCH₃ 71. N(CH₂CH₂OH)NHCH₂CH₃ 72. N(CH₂CH₂OH)NH(CH₂)₂CH₃ 73. N(CH₂CH₂OH)NH(CH₂)₃CH₃ 74. N(CH₂CH₂OH)NHCH(CH₃)₂ 75. N(CH₂CH₂OH)NHC(CH₃)₃ 76. N(CH₂CH₂OH)N(CH₃)₂ 77. N(CH₂CH₂OH)N(CH₂CH₃)₂ 78. N(CH₂CH₂OH)N[(CH₂)₂CH₃]₂ 79. N(CH₂CH₂OH)N[(CH₂)₃CH₃]₂ 80. N(CH₂CH₂OH)N[CH(CH₃)₂]₂ 81. N(CH₂CH₂OH)N(CH₃)CH₂CH₃ 82. NHNHCH₂CH₂OH 83. NHN(CH₃)CH₂CH₂OH 84. NHN(CH₂CH₃)CH₂CH₂OH 85. NHN(CH₂CH₂OH)₂ 86. N(CH₃)NHCH₂CH₂OH 87. N(CH₃)N(CH₃)CH₂CH₂OH 88. N(CH₃)N(CH₂CH₃)CH₂CH₂OH 89. N(CH₃)N(CH₂CH₂OH)₂ 90. N(CH₂CH₃)NHCH₂CH₂OH 91. N(CH₂CH₃)N(CH₃)CH₂CH₂OH 92. N(CH₂CH₃)N(CH₂CH₃)CH₂CH₂OH 93. N(CH₂CH₃)N(CH₂CH₂CH)₂ 94. N(CH₂CH₂CH)NHCH₂CH₂CH 95. N(CH₂CH₂CH)N(CH₂CH₂CH)₂ 96. N(CH₂CH₂OCH₃)NH₂ 97. N(CH₂CH₂OCH₃)NHCH₃ 98. N(CH₂CH₂OCH₃)NHCH₂CH₃ 99. N(CH₂CH₂OCH₃)NH(CH₂)₂CH₃ 100. N(CH₂CH₂OCH₃)NH(CH₂)₃CH₃ 101. N(CH₂CH₂OCH₃)NHCH(CH₃)₂ 102. N(CH₂CH₂OCH₃)NHC(CH₃)₃ 103. N(CH₂CH₂OCH₃)N(CH₃)₂ 104. N(CH₂CH₂OCH₃)N(CH₂CH₃)₂ 105. N(CH₂CH₂OCH₃)N[(CH₂)₂CH₃]₂ 106. N(CH₂CH₂OCH₃)N[(CH₂)₃CH₃]₂ 107. N(CH₂CH₂OCH₃)N[CH(CH₃)₂]₂ 108. N(CH₂CH₂OCH₃)N(CH₃)CH₂CH₃ 109. NHNHCH₂CH₂OCH₃ 110. NHN(CH₃)CH₂CH₂OCH₃ 111. NHN(CH₂CH₃)CH₂CH₂OCH₃ 112. NHN(CH₂CH₂OCH₃)₂ 113. N(CH₃)NHCH₂CH₂OCH₃ 114. N(CH₃)N(CH₃)CH₂CH₂OCH₃ 115. N(CH₃)N(CH₂CH₃)CH₂CH₂OCH₃ 116. N(CH₃)N(CH₂CH₂OCH₃)₂ 117. N(CH₂CH₃)NHCH₂CH₂OCH₃ 118. N(CH₂CH₃)N(CH₃)CH₂CH₂OCH₃ 119. N(CH₂CH₃)N(CH₂CH₃)CH₂CH₂OCH₃ 120. N(CH₂CH₃)N(CH₂CH₂OCH₃)₂ 121. N(CH₂CH₂OCH₃)NH—CH₂CH₂OCH₃ 122. N(CH₂CH₂OCH₃)N—(CH₂CH₂OCH₃)₂ 123. NHNHCH₂CH 124. NHNHCH₂OCH₃ 125. NHNHCH₂OCH₂CH₃ 126. NHN(CH₃)CH₂OH 127. NHN(CH₃)CH₂OCH₃ 128. NHN(CH₃)CH₂OCH₂CH₃ 129. N(CH₃)NHCH₂CH 130. N(CH₃)NHCH₂OCH₃ 131. N(CH₃)NHCH₂OCH₂CH₃ 132. N(CH₃)N(CH₃)CH₂OH 133. N(CH₃)N(CH₃)CH₂OCH₃ 134. N(CH₃)N(CH₃)CH₂OCH₂CH₃ 135. N(CH₂CH)NHCH₂CH 136. N(CH₂OCH₃)NHCH₂OCH₃ 137. N(CH₂OCH₂CH₃)NH—CH₂OCH₂CH₃ 138. N(CH₂CH)N(CH₃)CH₂OH 139. N(CH₂OCH₃)N(CH₃)CH₂OCH₃ 140. N(CH₂OCH₂CH₃)—N(CH₃)CH₂OCH₃CH₃ 141. NHNHCH(CH₃)CH₂OH 142. NHN(CH₃)CH(CH₃)CH₂OH 143. N(CH₃)NHCH(CH₃)CH₂OH 144. N(CH₃)N(CH₃)CH(CH₃)CH₂OH 145. NHNHCH(CH₃)CH₂OCH₃ 146. NHN(CH₃)CH(CH₃)CH₂OCH₃ 147. N(CH₃)NHCH(CH₃)CH₂OCH₃ 148. N(CH₃)N(CH₃)CH(CH₃)CH₂OCH₃ 149. NHNHCH(CH₂CH₃)CH₂OH 150. NHN(CH₃)CH(CH₂CH₃)CH₂OH 151. N(CH₃)NHCH(CH₂CH₃)CH₂OH 152. N(CH₃)N(CH₃)—CH(CH₂CH₃)CH₂OH 153. NHNHCH(CH₂CH₃)CH₂OCH₃ 154. NHN(CH₃)CH(CH₂CH₃)CH₂OCH₃ 155. N(CH₃)NHCH(CH₂CH₃)CH₂OCH₃ 156. N(CH₃)N(CH₂CH₃)—CH(CH₂CH₃)CH₂OCH₃ 157. NHN(CH₂CH₃)—CH(CH₂CH₃)CH₂OH 158. N(CH₃)N(CH₂CH₃)—CH(CH₂CH₃)CH₂OH 159. NHN(CH₂CH₃)—CH(CH₂CH₃)CH₂OCH₃ 160. N(CH₃)N(CH₂CH₃)—CH(CH₂CH₃)CH₂OCH₃ 161. NHNHCHO 162. NHNHC(O)CH₃ 163. NHNHC(O)CH₂CH₃ 164. NHNHC(O)CH₂CH₂OCH₃ 165. NHNHC(O)CF₃ 166. NHNHC(O)CF₂CF₃ 167. NHNHC(O)(CF₂)₂CF₃ 168. N(CHO)NH₂ 169. N[C(O)CH₃]NH₂ 170. N[C(O)CH₂CH₃]NH₂ 171. N[C(O)CH₂CH₂OCH₃]NH₂ 172. N[C(O)CF₃]NH₂ 173. N[C(O)CF₂CF₃]NH₂ 174. N[C(O)(CF₂)₂CF₃]NH₂ 175. N(CHO)NH(CHO) 176. N[C(O)CH₃]NH[C(O)CH₃) 177. N[C(O)CH₂CH₃]NH[C(O)CH₂CH₃] 178. N[C(O)CH₂CH₂OCH₃]NH—[C(O)CH₂CH₂OCH₃] 179. N[C(O)CF₃]NH[C(O)CF₃] 180. N[C(O)CF₂CF₃]NH[C(O)CF₂CF₃] 181. N[C(O)(CF₂)₂CF₃]NH—[C(O)(CF₂)₂CF₃] 182. NHN(CHO)₂ 183. NHN[C(O)CH₃]₂ 184. NHN[C(O)CH₂CH₃]₂ 185. NHN[C(O)CH₂CH₂OCH₃]₂ 186. NHN[C(O)CF₃]₂ 187. NHN[C(O)CF₂CF₃]₂ 188. NHN[C(O)(CF₂)₂CF₃]₂ 189. N(CH₃)NHCHO 190. N(CH₃)NHC(O)CH₃ 191. N(CH₃)NHC(O)CH₂CH₃ 192. N(CH₃)NHC(O)CH₂CH₂OCH₃ 193. N(CH₃)NHC(O)CF₃ 194. N(CH₃)NHC(O)CF₂CF₃ 195. N(CH₃)NHC(O)(CF₂)₂CF₃ 196. N(CHO)NH(CH₃) 197. N[C(O)CH₃]NH(CH₃) 198. N[C(O)CH₂CH₃]NH(CH₃) 199. N[C(O)CH₂CH₂OCH₃]NH(CH₃) 200. N[C(O)CF₃]NH(CH₃) 201. N[C(O)CF₂CF₃]NH(CH₃) 202. N[C(O)(CF₂)₂CF₃]NH(CH₃) 203. N(CHO)N(CH₃)(CHO) 204. N[C(O)CH₃]N(CH₃)[C(O)CH₃] 205. N[C(O)CH₂CH₃]—N(CH₃)[C(O)CH₂CH₃] 206. N[C(O)CH₂CH₂OCH₃]N(CH₃)—[C(O)CH₂CH₂OCH₃] 207. N[C(O)CF₃]N(CH₃)[C(O)CF₃] 208. N[C(O)CF₂CF₃]—N(CH₃)[C(O)CF₂CF₃] 209. N[O(O)(CF₂)₂CF₃]N(CH₃)—[C(O)(CF₂)₂CF₃] 210. N(CH₃)N(CHO)₂ 211. N(CH₃)N[C(O)CH₃]₂ 212. N(CH₃)N[O(O)CH₂CH₃]₂ 213. N(CH₃)N[C(O)CH₂CH₂OCH₃]₂ 214. N(CH₃)N[C(O)CF₃]₂ 215. N(CH₃)N[C(O)CF₂CF₃]₂ 216. N(CH₃)N[C(O)(CF₂)₂CF₃]₂ 217. N(CH₃)N(CH₃)CHO 218. N(CH₃)N(CH₃)C(O)CH₃ 219. N(CH₃)N(CH₃)C(O)CH₂CH₃ 220. N(CH₃)N(CH₃)C(O)CH₂CH₂OCH₃ 221. N(CH₃)N(CH₃)C(O)CF₃ 222. N(CH₃)N(CH₃)C(O)CF₂CF₃ 223. N(CH₃)N(CH₃)C(O)(CF₂)₂CF₃ 224. N(CHO)N(CH₃)₂ 225. N[C(O)CH₃]N(CH₃)₂ 226. N[C(O)CH₂CH₃]N(CH₃)₂ 227. N[C(O)CH₂CH₂OCH₃]N(CH₃)₂ 228. N[C(O)CF₃]N(CH₃)₂ 229. N[C(O)CF₂CF₃]N(CH₃)₂ 230. N[C(O)(CF₂)₂CF₃]N(CH₃)₂ 231.

232.

233.

234.

235.

236.

237.

238.

239.

240.

241. NH₂ 242. NH(CH₃) 243. NH(CH₂CH₃) 244. NH[(CH₂)₂CH₃] 245. NH[(CH₂)₃CH₃] 246. NH[(CH₂)₄CH₃] 247. NH[CH(CH₃)₂] 248. NH[CH(CH₂CH₃)₂] 249. NH[C(CH₃)₃] 250. NH[CH(CH₃)CH₂CH₃] 251. NH[CH₂CH(CH₃)₂] 252. N(CH₃)₂ 253. NCH₃(CH₂CH₃) 254. NCH₃[(CH₂)₂CH₃] 255. NCH₃[(CH₂)₃CH₃] 256. NCH₃[(CH₂)₄CH₃] 257. NCH₃[CH(CH₃)₂] 258. NCH₃[CH(CH₂CH₃)₂] 259. NCH₃[C(CH₃)₃] 260. NCH₃[CH(CH₃)CH₂CH₃] 261. NCH₃[CH₂CH(CH₃)₂] 262. NCH₃(CH₂CH₃) 263. N(CH₂CH₃)₂ 264. NCH₂CH₃[(CH₂)₂CH₃] 265. NCH₂CH₃[(CH₂)₃CH₃] 266. NCH₂CH₃[(CH₂)₄CH₃] 267. NCH₂CH₃[CH(CH₃)₂] 268. NCH₂CH₃[CH(CH₂CH₃)₂] 269. NCH₂CH₃[C(CH₃)₃] 270. NCH₂CH₃[CH(CH₃)CH₂CH₃] 271. NCH₂CH₃[CH₂CH(CH₃)₂] 272. NH(CH₂CH₂NH₂) 273. NH[(CH₂)₃NH₂] 274. NH[CH(CH₃)CH₂NH₂] 275. NH[CH(CH₃)CH₂CH₂NH₂ 276. NH[CH(CH₂CH₃)CH₂NH₂] 277. NH[CH(i-propyl)CH₂NH₂] 278. NH(CH₂CH₂NHCH₃) 279. NH[(CH₂)₃NHCH₃] 280. NH[CH(CH₃)CH₂CH₂NHCH₃ 281. NH[CH(CH₃)CH₂NHCH₃] 282. NH[CH(CH₂CH₃)CH₂NHCH₃] 283. NH[CH(i-propyI)CH₂NHCH₃] 284. NH(CH₂CH₂N(CH₃)₂) 285. NH[(CH₂)₃N(CH₃)₂] 286. NH[CH(CH₃)CH₂CH₂N(CH₃)₂ 287. NH[CH(CH₃)CH₂N(CH₃)₂] 288. NH[CH(CH₂CH₃)CH₂N(CH₃)₂] 289. NH[CH(i-propyl)CH₂N(CH₃)₂] 290. NCH₃(CH₂CH₂NH₂) 291. NCH₃[(CH₂)₃NH₂] 292. NCH₃[CH(CH₃)CH₂NH₂] 293. NCH₃[CH(CH₃)CH₂CH₂NH₂ 294. NCH₃[CH(CH₂CH₃)CH₂NH₂] 295. NCH₃[CH(i-propyl)CH₂NH₂] 296. NCH₃(CH₂CH₂NHCH₃) 297. NCH₃[(CH₂)₃NHCH₃] 298. NCH₃[CH(CH₃)CH₂NHCH₃] 299. NCH₃[CH(CH₃)CH₂CH₂NHCH₃] 300. NCH₃[CH(CH₂CH₃)CH₂NHCH₃] 301. NCH₃[CH(i-propyl)CH₂NHCH₃) 302. NCH₃(CH₂CH₂N(CH₃)₂) 303. NCH₃[(CH₂)₃N(CH₃)₂] 304. NCH₃[CH(CH₃)CH₂N(CH₃)₂] 305. NCH₃[CH(CH₃)CH₂CH₂N(CH₃)₂] 306. NCH₃[CH(CH₂CH₃)CH₂N(CH₃)₂] 307. NCH₃[CH(i-propyl)CH₂N(CH₃)₂] 308. NH[CH₂CH₂OCH₂OCH₃] 309. NH[CH(CH₃)CH₂OCH₂OCH₃] 310. NH[CH₂CH₂OCH₂OCH₂CH₃] 311. NH[CH(CH₃)CH₂OCH₂OCH₂CH₃] 312. NH[CH(CH₂CH₃)CH₂OCH₂OCH₃] 313. NH[CH(CH₂CH₃)CH₂O—CH₂OCH₂CH₃] 314. NCH₃[CH₂CH₂OCH₂OCH₃] 315. NCH₃[CH(CH₃)CH₂OCH₂OCH₃] 316. NCH₃[CH₂CH₂OCH₂OCH₂CH₃] 317. NCH₃[CH(CH₃)CH₂O—CH₂OCH₂CH₃] 318. NCH₃[CH(CH₂CH₃)CH₂O—CH₂OCH₃] 319. NCH₃[CH(CH₂CH₃)CH₂O—CH₂OCH₂CH₃] 320. NCH₂OCH₃[CH₂CH₂OCH₂OCH₃] 321. NCH₂OCH₃[CH(CH₃)CH₂O—CH₂OCH₃] 322. NCH₂OCH₃[CH₂CH₂O—CH₂OCH₂CH₃] 323. NCH₂OCH₃[CH(CH₃)CH₂O—CH₂OCH₂CH₃] 324. NCH₂OCH₃[CH(CH₂CH₃)CH₂O—CH₂OCH₃] 325. NCH₂OCH₃[CH(CH₂CH₃)CH₂O—CH₂OCH₂CH₃] 326. NHCH₂CH₂NHCH₂CH₂OH 327. NHCH(CH₃)CH₂NHCH₂CH₂OH 328. NHCH(CH₂CH₃)CH₂NH—CH₂CH₂OH 329. NHCH(CH(CH₃)₂)CH₂NH—CH₂CH₂OH 330. NHCH₂CH₂NH(CH₂)₃OH 331. NHCH(CH₃)CH₂NH(CH₂)₃OH 332. NHCH(CH₂CH₃)CH₂NH—(CH₂)₃OH 333. NHCH(CH(CH₃)₂)CH₂NH—(CH₂)₃OH 334. NHCH₂CH₂NHCH(CH₃)CH₂OH 335. NHCH(CH₃)CH₂NH—CH(CH₃)CH₂OH 336. NHCH(CH₂CH₃)CH₂NH—CH(CH₃)CH₂OH 337. NHCH(CH(CH₃)₂)CH₂NH—CH(CH₃)CH₂OH 338. NHCH₂CH₂NHCH₂CH(CH₃)OH 339. NHCH(CH₃)CH₂NH—CH₂CH(CH₃)OH 340. NHCH(CH₂CH₃)CH₂NH—CH₂CH(CH₃)OH 341 NHCH(CH(CH₃)₂)CH₂NH—CH₂CH(CH₃)OH 342. NHCH₂CN 343. NH(CH₂)₂CN 344. NH(CH₂)₃CN 345. NH(CH₂)₄CN 346. NHCH(CH₃)CN 347. NHCH(CH₃)CH₂CN 348. NHCH(CH₂CH₃)CN 349. NHCH(CH₂CH₃)CH₂CN 350. NHCH(CH(CH₃)₂)CN 351. NHCH(CH(CH₃)₂)CH₂CN 352. N(CH₃)CH₂CN 353. N(CH₃)(CH₂)₂CN 354. N(CH₃)(CH₂)₃CN 355. N(CH₃)(CH₂)₄CN 356. N(CH₃)CH(CH₃)CN 357. N(CH₃)CH(CH₃)CH₂CN 358. N(CH₃)CH(CH₂CH₃)CN 359. N(CH₃)CH(CH₂CH₃)CHCN 360. N(CH₃)CH(CH(CH₃)₂)CN 361. N(CH₃)CH(CH(CH₃)₂)CH₂CN 362. N(CH₂CN)₂ 363. N(CH₂CH₂CN)₂ 364. NHCH₂F 365. NHCH₂CH₂F 366. NHCH₂CF₃ 367. NHCH₂CF₂CF₃ 368. N(CH₃)CH₂F 369. N(CH₃)CH₂CH₂F 370. N(CH₃)CH₂CF₃ 371. N(CH₃)CH₂CF₂CF₃ 372. N(CHO)CH₂F 373. N(CHO)CH₂CH₂F 374. N(CHO)CH₂CF₃ 375. N(CHO)CH₂CF₂CF₃ 376. N(COCH₃)CH₂F 377. N(COCH₃)CH₂CH₂F 378. N(COCH₃)CH₂CF₃ 379. N(COCH₃)CH₂CF₂CF₃ 380. N(CH₂F)₂ 381. N(CH₂CH₂F)₂ 382. N(CH₂CF₃)₂ 383. N(CH₂CF₂CF₃)₂ 384. NH(CH₂CH═CH₂) 385. NH(CH₂CH═CHCH₃) 386. NH(CH₂CH═C(CH₃)₂) 387. NH(CH(CH₃)CH═CH₂) 388. NH(CH(CH₃)CH═CHCH₃) 389. NH(CH(CH₃)CH═C(CH₃)₂) 390. NH(CH(CH₂CH₃)CH═CH₂) 391. NH(CH(CH₂CH₃)CH═CHCH₃) 392. NH(CH(CH₂CH₃)CH═C(CH₃)₂) 393. NH(CH[CH(CH₃)₂]CH═CH₂) 394. NH(CH[CH(CH₃)₂]CH═CHCH₃) 395. NH(CH[CH(CH₃)₂]CH═C(CH₃)₂) 396. N(CH₃)(CH₂CH═CH₂) 397. N(CH₃)(CH₂CH═CHCH₃) 398. N(CH₃)(CH₂CH═C(CH₃)₂) 399. N(CH₃)(CH(CH₃)CH═CH₂) 400. N(CH₃)(CH(CH₃)CH═CHCH₃) 401. N(CH₃)(CH(CH₃)CH═C(CH₃)₂) 402. N(CH₃)(CH(CH₂CH₃)CH═CH₂) 403. N(CH₃)(CH(CH₂CH₃)CH═CHCH₃) 404. N(CH₃)—(CH(CH₂CH₃)CH═C(CH₃)₂) 405. N(CH₃)(CH[CH(CH₃)₂]CH═CH₂) 406. N(CH₃)(CH[CH(CH₃)₂]CH═CHCH₃) 407. N(CH₃)—(CH[CH(CH₃)₂]CH═C(CH₃)₂) 408. NH(CH₂C≡CH) 409. NH(CH₂C≡CCH₃) 410. NH(CH(CH₃)C≡CH) 411. NH(CH(CH₃)C≡CCH₃) 412. NH(CH(CH₂CH₃)C≡CH) 413. NH(CH(CH₂CH₃)C≡CCH₃) 414. NH(CH[CH(CH₃)₂]C≡CH) 415. NH(CH[CH(CH₃)₂]C≡CCH₃) 416. N(CH₃)(CH₂C≡CH) 417. N(CH₃)(CH₂C≡CCH₃) 418. N(CH₃)(CH(CH₃)C≡CH) 419. N(CH₃)(CH(CH₃)C≡CCH₃) 420. N(CH₃)(CH(CH₂CH₃)C≡CH) 421. N(CH₃)(CH(CH₂CH₃)C≡CCH₃) 422. N(CH₃)(CH[CH(CH₃)₂]C≡CH) 423. N(CH₃)(CH[CH(CH₃)₂]C≡CCH₃) 424. N(CH₃)—(CH[CH(CH₃)₂]C≡C(CH₃)₂) 425. NHCH₂CH₂NHC(O)H 426. NHCH₂CH₂NHC(O)CH₃ 427. NHCH₂CH₂NH—C(O)CH₂CH₃ 428. NHCH₂CH₂NH—C(O)CF₃ 429. NHCH₂CH₂NH—C(O)(CH₂)₂CH₃ 430. NHCH₂CH₂NH—C(O)CH₂OH 431. NHCH₂CH₂NH—C(O)CH₂OCH₃ 432. NHCH₂CH₂NH—C(O)CH(CH₃)OH 433. NHCH₂CH₂NH—C(O)CH(CH₃)OCH₃ 434. NHCH₂CH₂NH—C(O)CH₂CH(CH₃)OH 435. NHCH₂CH₂NH—C(O)CH₂CH(CH₃)OCH₃ 436. NNCH₂CH₂NH—C(O)CH(CH₃)CH₂OH 437. NHCH₂CH₂NH C(O)CH(CH₃)CH₂OCH₃ 438. NHCH₂CH₂CH₂NHC(O)H 439. NHCH₂CH₂CH₂NH—C(O)CH₃ 440. NHCH₂CH₂CH₂NH—C(O)CH₂CH₃ 441. NHCH₂CH₂CH₂NH—C(O)CF₃ 442. NHCH₂CH₂CH₂NH—C(O)(CH₂)₂CH₃ 443. NHCH₂CH₂CH₂NH—C(O)CH₂OH 444. NHCH₂CH₂CH₂NH—C(O)CH₂OCH₃ 445. NHCH₂CH₂CH₂NH—C(O)CH(CH₃)OH 446. NHCH₂CH₂CH₂NH—C(O)CH(CH₃)OCH₃ 447. NHCH₂CH₂CH₂NH—C(O)CH₂CH(CH₃)OH 448. NHCH₂CH₂CH₂NH—C(O)CH₂CH(CH₃)OCH₃ 449. NHCH₂CH₂CH₂NH—C(O)CH(CH₃)CH₂OH 450. NHCH₂CH₂CH₂NH—C(O)CH(CH₃)CH₂OCH₃ 451. NHCH(CH₃)CH₂NHC(O)H 452. NHCH(CH₃)CH₂NH—C(O)CH₃ 453. NHCH(CH₃)CH₂NH—C(O)CH₂CH₃ 454. NHCH(CH₃)CH₂NH—C(O)CF₃ 455. NHCH(CH₃)CH₂NH—C(O)(CH₂)₂CH₃ 456. NHCH(CH₃)CH₂NH—C(O)CH₂OH 457. NHCH(CH₃)CH₂NH—C(O)CH₂OCH₃ 458. NHCH(CH₃)CH₂NH—C(O)CH(CH₃)OH 459. NHCH(CH₃)CH₂NH—C(O)CH(CH₃)OCH₃ 460. NHCH(CH₃)CH₂NH—C(O)CH₂CH(CH₃)OH 461. NHCH(CH₃)CH₂NH—C(O)CH₂CH(CH₃)OCH₃ 462. NHCH(CH₃)CH₂NH—C(O)CH(CH₃)CH₂OH 463. NHCH(CH₃)CH₂NH—C(O)CH(CH₃)CH₂OCH₃ 464. NHCH(CH₃)CH₂CH₂NH—C(O)H 465. NHCH(CH₃)CH₂CH₂NH—C(O)CH₃ 466. NHCH(CH₃)CH₂CH₂NH—C(O)CH₂CH₃ 467. NHCH(CH₃)CH₂CH₂NH—C(O)CF₃ 468. NHCH(CH₃)CH₂CH₂NH—C(O)(CH₂)₂CH₃ 469. NHCH(CH₃)CH₂CH₂NH—C(O)CH₂OH 470. NHCH(CH₃)CH₂CH₂NH—C(O)CH₂OCH₃ 471. NHCH(CH₃)CH₂CH₂NH—C(O)CH(CH₃)OH 472. NHCH(CH₃)CH₂CH₂NH—C(O)CH(CH₃)OCH₃ 473. NHCH(CH₃)CH₂CH₂NH—C(O)CH₂CH(CH₃)OH 474. NHCH(CH₃)CH₂CH₂NH—C(O)CH₂CH(CH₃)OCH₃ 475. NHCH(CH₃)CH₂CH₂NH—C(O)CH(CH₃)CH₂OH 476. NHCH(CH₃)CH₂CH₂NH—C(O)CH(CH₃)CH₂OCH₃ 477. NHCH(CH₂CH₃)CH₂NHC(O)H 478. NHCH(CH₂CH₃)CH₂NH— C(O)CH₃ 479. NHCH(CH₂CH₃)CH₂NH— C(O)CH₂CH₃ 480. NHCH(CH₂CH₃)CH₂NH— C(O)CF₃ 481. NHCH(CH₂CH₃)CH₂NH— C(O)(CH₂)₂CH₃ 482. NHCH(CH₂CH₃)CH₂NH— C(O)CH₂OH 483. NHCH(CH₂CH₃)CH₂NH— C(O)CH₂OCH₃ 484. NHCH(CH₂CH₃)CH₂NH— C(O)CH(CH₃)OH 485. NHCH(CH₂CH₃)CH₂NH— C(O)CH(CH₃)OCH₃ 486. NHCH(CH₂CH₃)CH₂NH— C(O)CH₂CH(CH₃)OH 487. NHCH(CH₂CH₃)CH₂NH— C(O)CH₂CH(CH₃)OCH₃ 488. NHCH(CH₂CH₃)CH₂NH— C(O)CH(CH₃)CH₂OH 489. NHCH(CH₂CH₃)CH₂NH— C(O)CH(CH₃)CH₂OCH₃ 490. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)H 491. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH₃ 492. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH₂CH₃ 493. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CF₃ 494. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)(CH₂)₂CH₃ 495. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH₂OH 496. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH₂OCH₃ 497. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)OH 498. NHCH(CH₂CH₃)CH₂CH₂NI-I— C(O)CH(CH₃)OCH₃ 499. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH₂CH(CH₃)OH 500. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH₂CH(CH₃)OCH₃ 501. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)CH₂OH 502. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)CH₂OCH₃ 503. NHCH(CH₂CH₂CH₃)CH₂NHC(O)H 504. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH₃ 505. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH₂CH₃ 506. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CF₃ 507. NHCH(CH₂CH₂CH3)CH₂NH— C(O)(CH₂)₂CH₃ 508. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH₂OH 509. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH₂OCH₃ 510. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH(CH₃)OH 511. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH(CH₃)OCH₃ 512. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH₂CH(CH₃)OH 513. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH₂CH(CH₃)OCH₃ 514. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH(CH₃)CH₂OH 515. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)CH(CH₃)CH₂OCH₃ 516. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)H 517. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH₃ 518. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH₂CH₃ 519. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CF₃ 520. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)(CH₂)₂CH₃ 521. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH₂OH 522. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH₂OCH₃ 523. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)OH 524. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)OCH₃ 525. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH₂CH(CH₃)OH 526. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH₂CH(CH₃)OCH₃ 527. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)CH₂OH 528. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)CH(CH₃)CH₂OCH₃ 529. NHCH(CH(CH₃)₂)CH₂NHC(O)H 530. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH₃ 531. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH₂CH₃ 532. NHCH(CH(CH₃)₂)CH₂NH— C(O)CF₃ 533. NHCH(CH(CH₃)₂)CH₂NH— C(O)(CH₂)₂CH₃ 534. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH₂OH 535. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH₂OCH₃ 536. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH(CH₃)OH 537. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH(CH₃)OCH₃ 538. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH₂CH(CH₃)OH 539. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH(CH(CH₃)₂)OCH₃ 540. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH(CH₃)CH₂OH 541. NHCH(CH(CH₃)₂)CH₂NH— C(O)CH(CH₃)CH₂OCH₃ 542. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)H 543. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH₃ 544. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH₂CH₃ 545. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CF₃ 546. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)(CH₂)₂CH₃ 547. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH₂OH 548. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH₂OCH₃ 549. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH(CH₃)OH 550. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH(CH₃)OCH₃ 551. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH₂CH(CH₃)OH 552. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH₂CH(CH₃)OCH₃ 553. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH(CH₃)CH₂OH 554. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)CH(CH₃)CH₂OCH₃ 555. NHCH₂CH₂NHC(O)OCH₃ 556. NHCH₂CH₂NH— C(O)OCH₂CH₃ 557. NHCH₂CH₂NH— C(O)O(CH₂)₂CH₃ 558. NHCH₂CH₂NH— C(O)OCH(CH₃)OH 559. NHCH₂CH₂NH—C(O)OCH(CH₃)OCH₃ 560. NHCH₂CH₂NH— C(O)OCH₂CH(CH₃)OH 561. NHCH₂CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 562. NHCH₂CH₂NH— O(O)OCH(CH₃)CH₂OH 563. NHCH₂CH₂NH C(O)OCH(CH₃)CH₂OCH₃ 564. NHCH₂CH₂CH₂NH— C(O)OCH₃ 565. NHCH₂CH₂CH₂NH— C(O)OCH₂CH₃ 566. NHCH₂CH₂CH₂NH—C(O)O(CH₂)₂CH₃ 567. NHCH₂CH₂CH₂NH— C(O)OCH(CH₃)OH 568. NHCH₂CH₂CH₂NH— C(O)OCH(CH₃)OCH₃ 569. NHCH₂CH₂CH₂NH— C(O)OCH₂CH(CH₃)OH 570. NHCH₂CH₂CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 571. NHCH₂CH₂CH₂NH— C(O)OCH(CH₃)CH₂OH 572. NHCH₂CH₂CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 573. NHCH(CH₃)CH₂NH— C(O)OCH₃ 574. NHCH(CH₃)CH₂NH— C(O)OCH₂CH₃ 575. NHCH(CH₃)CH₂NH— C(O)O(CH₂)₂CH₃ 576. NHCH(CH₃)CH₂NH— C(O)OCH(CH₃)OH 577. NHCH(CH₃)CH₂NH— C(O)OCH(CH₃)OCH₃ 578. NHCH(CH₃)CH₂NH— C(O)OCH₂CH(CH₃)OH 579. NHCH(CH₃)CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 580. NHCH(CH₃)CH₂NH— C(O)OCH(CH₃)CH₂OH 581. NHCH(CH₃)CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 582. NHCH(CH₃)CH₂CH₂NH— C(O)OCH₃ 583. NHCH(CH₃)CH₂CH₂NH— C(O)OCH₂CH₃ 584. NHCH(CH₃)CH₂CH₂NH— C(O)O(CH₂)₂CH₃ 585. NHCH(CH₃)CH₂CH₂NH— C(O)OCH(CH₃)OH 586. NHCH(CH₃)CH₂CH₂NH— C(O)OCH(CH₃)OCH₃ 587. NHCH(CH₃)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OH 588. NHCH(CH₃)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 589. NHCH(CH₃)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OH 590. NHCH(CH₃)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 591. NHCH(CH₂CH₃)CH₂NH— C(O)OCH₃ 592. NHCH(CH₂CH₃)CH₂NH— C(O)OCH₂CH₃ 593. NHCH(CH₂CH₃)CH₂NH— C(O)O(CH₂)₂CH₃ 594. NHCH(CH₂CH₃)CH₂NH— C(O)OCH(CH₃)OH 595. NHCH(CH₂CH₃)CH₂NH— C(O)OCH(CH₃)OCH₃ 596. NHCH(CH₂CH₃)CH₂NH— C(O)OCH₂CH(CH₃)OH 597. NHCH(CH₂CH₃)CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 598. NHCH(CH₂CH₃)CH₂NH— C(O)OCH(CH₃)CH₂OH 599. NHCH(CH₂CH₃)CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 600. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH₃ 601. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH₂CH₃ 602. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)O(CH₂)₂CH₃ 603. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)OH 604. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)OCH₃ 605. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OH 606. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 607. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OH 608. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 609. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH₃ 610. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH₂CH₃ 611. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)O(CH₂)₂CH₃ 612. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH₂OCH₃ 613. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH(CH₃)OH 614. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH(CH₃)OCH₃ 615. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH₂CH(CH₃)OH 616. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 617. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH(CH₃)CH₂OH 618. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 619. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH₃ 620. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH₂CH₃ 621. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)O(CH₂)₂CH₃ 622. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)OH 623. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)OCH₃ 624. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OH 625. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 626. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OH 627. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 628. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH₃ 629. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH₂CH₃ 630. NHCH(CH(CH₃)₂)CH₂NH— C(O)O(CH₂)₂CH₃ 631. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH(CH₃)OCH₃ 632. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH₂CH(CH₃)OH 633. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH(CH(CH₃)₂)OCH₃ 634. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH(CH₃)CH₂OH 635. NHCH(CH(CH₃)₂)CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 636. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH₃ 637. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH₂CH₃ 638. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)O(CH₂)₂CH₃ 639. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH(CH₃)OCH₃ 640. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OH 641. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH₂CH(CH₃)OCH₃ 642. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OH 643. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)OCH(CH₃)CH₂OCH₃ 644. NHCH₂CH₂NHC(O)NHCH₃ 645. NHCH₂CH₂NH— C(O)NHCH₂CH₃ 646. NHCH₂CH₂NH— C(O)NH(CH₂)₂CH₃ 647. NHCH₂CH₂NH— C(O)NHCH(CH₃)OH 648. NHCH₂CH₂NH— C(O)NHCH(CH₃)OCH₃ 649. NHCH₂CH₂NH— C(O)NHCH₂CH(CH₃)OH 650. NHCH₂CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 651. NHCH₂CH₂NH— C(O)NHCH(CH₃)CH₂OH 652. NHCH₂CH₂NH C(O)NHCH(CH₃)CH₂OCH₃ 653. NHCH₂CH₂CH₂NH— C(O)NHCH₃ 654. NHCH₂CH₂CH₂NH— C(O)NHCH₂CH₃ 655. NHCH₂CH₂CH₂NH— C(O)NH(CH₂)₂CH₃ 656. NHCH₂CH₂CH₂NH— C(O)NHCH(CH₃)OH 657. NHCH₂CH₂CH₂NH— C(O)NHCH(CH₃)OCH₃ 658. NHCH₂CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OH 659. NHCH₂CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 660. NHCH₂CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OH 661. NHCH₂CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 662. NHCH(CH₃)CH₂NH— C(O)NHCH₃ 663. NHCH(CH₃)CH₂NH— C(O)NHCH₂CH₃ 664. NHCH(CH₃)CH₂NH— C(O)NH(CH₂)₂CH₃ 665. NHCH(CH₃)CH₂NH— C(O)NHCH(CH₃)OH 666. NHCH(CH₃)CH₂NH— C(O)NHCH(CH₃)OCH₃ 667. NHCH(CH₃)CH₂NH— C(O)NHCH₂CH(CH₃)OH 668. NHCH(CH₃)CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 669. NHCH(CH₃)CH₂NH— C(O)NHCH(CH₃)CH₂OH 670. NHCH(CH₃)CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 671. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH₃ 672. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH₂CH₃ 673. NHCH(CH₃)CH₂CH₂NH— C(O)NH(CH₂)₂CH₃ 674. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)OH 675. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)OCH₃ 676. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OH 677. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 678. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OH 679. NHCH(CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 680. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH₃ 681. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH₂CH₃ 682. NHCH(CH₂CH₃)CH₂NH— C(O)NH(CH₂)₂CH₃ 683. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)OH 684. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)OCH₃ 685. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH₂CH(CH₃)OH 686. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 687. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)CH₂OH 688. NHCH(CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 689. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH₃ 690. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH₂CH₃ 691. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NH(CH₂)₂CH₃ 692. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH₂OCH₃ 693. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)OH 694. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)OCH₃ 695. NHCH(CH2CH₃)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OH 696. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 697. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂ON 698. NHCH(CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 699. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH₃ 700. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH₂CH₃ 701. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NH(CH₂)₂CH₃ 702. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)OH 703. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH(CH₂)OCH₃ 704. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH₂CH(CH₃)OH 705. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 706. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)CH₂OH 707. NHCH(CH₂CH₂CH₃)CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 708. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH₃ 709. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH₂CH₃ 710. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NH(CH₂)₂CH₃ 711. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)OH 712. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)OCH₃ 713. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OH 714. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 715. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OH 716. NHCH(CH₂CH₂CH₃)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 717. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH₃ 718. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH₂CH₃ 719. NHCH(CH(CH₃)₂)CH₂NH— C(O)NH(CH₂)₂CH₃ 720. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH(CH₃)OCH₃ 721. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH₂CH(CH₃)OH 722. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH(CH(CH₃)₂)OCH₃ 723. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH(CH₃)CH₂OH 724. NHCH(CH(CH₃)₂)CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 725. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH₃ 726. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH₂CH₃ 727. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NH(CH₂)₂CH₃ 728. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH(CH₃)OCH₃ 729. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OH 730. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH₂CH(CH₃)OCH₃ 731. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OH 732. NHCH(CH(CH₃)₂)CH₂CH₂NH— C(O)NHCH(CH₃)CH₂OCH₃ 733. NHCH₂CH₂OC(O)H 734. NHCH₂CH₂OC(O)CH₃ 735. NHCHCH₂O— C(O)CH₂CH₃ 736. NHCH₂CH₂O— C(O)CF₃ 737. NHCH₂CH₂O— C(O)(CH₂)₂CH₃ 738. NHCH₂CH₂O— C(O)CH₂OH 739. NHCH₂CH₂O— C(O)CH₂OCH₃ 740. NHCH₂CH₂O— C(O)CH(CH₃)OH 741. NHCH₂CH₂OC(O)CH(CH₃)OCH₃ 742. NHCH₂CH₂O—C(O)CH₂CH(CH₃)OH 743. NHCH₂CH₂O— C(O)CH₂CH(CH₃)OCH₃ 744. NHCH₂CH₂O—C(O)CH(CH₃)CH₂OH 745. NHCH₂CH₂O— C(O)CH(CH₃)CH₂OCH₃ 746. NHCH₂CH₂CH₂OC(O)H 747. NHCH₂CH₂CH₂OC(O)CH₃ 748. NHCH₂CH₂CH₂O— C(O)CH₂CH₃ 749. NHCH₂CH₂CH₂OC(O)CF₃ 750. NHCH₂CH₂CH₂OC(O)(CH₂)₂CH₃ 751. NHCH₂CH₂CH₂OC(O)CH₂OH 752. NHCH₂CH₂CH₂O— C(O)CH₂OCH₃ 753. NHCH₂CH₂CH₂O—C(O)CH(CH₃)OH 754. NHCH₂CH₂CH₂O— C(O)CH(CH₃)OCH₃ 755. NHCH₂CH₂CH₂O— C(O)CH₂CH(CH₃)OH 756. NHCH₂CH₂CH₂O— C(O)CH₂CH(CH₃)OCH₃ 757. NHCH₂CH₂CH₂O— C(O)CH(CH₃)CH₂OH 758. NHCH₂CH₂CH₂O— C(O)CH(CH₃)CH₂OCH₃ 759. NHCH(CH₃)CH₂OC(O)H 760. NHCH(CH₃)CH₂OC(O)CH₃ 761. NHCH(CH₃)CH₂OC(O)CH₂CH₃ 762. NHCH(CH₃)CH₂OC(O)CF₃ 763. NHCH(CH₃)CH₂OC(O)(CH₂)₂CH₃ 764. NHCH(CH₃)CH₂OC(O)CH₂OH 765. NHCH(CH₃)CH₂OC(O)CH₂OCH₃ 766. NHCH(CH₃)CH₂OC(O)CH(CH₃)OH 767. NHCH(CH₃)CH₂O— C(O)CH(CH₃)OCH₃ 768. NHCH(CH₃)CH₂O— C(O)CH₂CH(CH₃)OH 769. NHCH(CH₃)CH₂O— C(O)CH₂CH(CH₃)OCH₃ 770. NHCH(CH₃)CH₂O— C(O)CH(CH₃)CH₂OH 771. NHCH(CH₃)CH₂0— C(O)CH(CH₃)CH₂OCH₃ 772. NHCH(CH₃)CH₂CH₂OC(O)H 773. NHCH(CH₃)CH₂CH₂OC(O)CH₃ 774. NHCH(CH₃)CH₂CH₂O—C(O)CH₂CH₃ 775. NHCH(CH₃)CH₂CH₂OC(O)CF₃ 776. NHCH(CH₃)CH₂CH₂O— C(O)(CH₂)₂CH₃ 777. NHCH(CH₃)CH₂CH₂OC(O)CH₂OH 778. NHCH(CH₃)CH₂CH₂O— C(O)CH₂OCH₃ 779. NHCH(CH₃)CH₂CH₂O— C(O)CH(CH₃)OH 780. NHCH(CH₃)CH₂CH₂O— C(O)CH(CH₃)OCH₃ 781. NHCH(CH₃)CH₂CH₂O— C(O)CH₂CH(CH₃)OH 782. NHCH(CH₃)CH₂CH₂O— C(O)CH₂CH(CH₃)OCH₃ 783. NHCH(CH₃)CH₂CH₂O— C(O)CH(CH₃)CH₂OH 784. NHCH(CH₃)CH₂CH₂O— C(O)CH(CH₃)CH₂OCH₃ 785. NHCH(CH₂CH₃)CH₂OC(O)H 786. NHCH(CH₂CH₃)CH₂OC(O)CH₃ 787. NHCH(CH₂CH₃)CH₂0— C(O)CH₂CH₃ 788. NHCH(CH₂CH₃)CH₂O— C(O)CF₃ 789. NHCH(CH₂CH₃)CH₂O— C(O)(CH₂)₂CH₃ 790. NHCH(CH₂CH₃)CH₂O—C(O)CH₂OH 791. NHCH(CH₂CH₃)CH₂O— C(O)CH₂OCH₃ 792. NHCH(CH₂CH₃)CH₂O— C(O)CH(CH₃)OH 793. NHCH(CH₂CH₃)CH₂O— C(O)CH(CH₃)OCH₃ 794. NHCH(CH₂CH₃)CH₂O— C(O)CH₂CH(CH₃)OH 795. NHCH(CH₂CH₃)CH₂O— C(O)CH₂CH(CH₃)OCH₃ 796. NHCH(CH₂CH₃)CH₂O— C(O)CH(CH₃)CH₂OH 797. NHCH(CH₂CH₃)CH₂O— C(O)CH(CH₃)CH₂OCH₃ 798. NHCH(CH₂CH₃)CH₂CH₂O— C(O)H 799. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH₃ 800. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH₂CH₃ 801. NHCH(CH₂CH₃)CH₂CH₂O—C(O)CF₃ 802. NHCH(CH₂CH₃)CH₂CH₂O— C(O)(CH₂)₂CH₃ 803. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH₂OH 804. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH₂OCH₃ 805. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)OH 806. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)OCH₃ 807. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH₂CH(CH₃)OH 808. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH₂CH(CH₃)OCH₃ 809. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)CH₂OH 810. NHCH(CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)CH₂OCH₃ 811. NHCH(CH₂CH₂CH₃)CH₂OC(O)H 812. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH₃ 813. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH₂CH₃ 814. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CF₃ 815. NHCH(CH₂CH₂CH₃)CH₂O— C(O)(CH₂)₂CH₃ 816. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH₂OH 817. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH₂OCH₃ 818. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH(CH₃)OH 819. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH(CH₃)OCH₃ 820. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH₂CH(CH₃)OH 821. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH₂CH(CH₃)OCH₃ 822. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH(CH₃)CH₂OH 823. NHCH(CH₂CH₂CH₃)CH₂O— C(O)CH(CH₃)CH₂OCH₃ 824. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)H 825. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH₃ 826. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH₂CH₃ 827. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CF₃ 828. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)(CH₂)₂CH₃ 829. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH₂OH 830. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH₂OCH₃ 831. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)OH 832. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)OCH₃ 833. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH₂CH(CH₃)OH 834. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH₂CH(CH₃)OCH₃ 835. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)CH₂OH 836. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)CH(CH₃)CH₂OCH₃ 837. NHCH(CH(CH₃)₂)CH₂OC(O)H 838. NHCH(CH(CH₃)₂)CH₂OC(O)CH₃ 839. NHCH(CH(CH₃)₂)CH₂O— C(O)CH₂CH₃ 840. NHCH(CH(CH₃)₂)CH₂OC(O)CF₃ 841. NHCH(CH(CH₃)₂)CH₂O— C(O)(CH₂)₂CH₃ 842. NHCH(CH(CH₃)₂)CH₂O— C(O)CH₂OH 843. NHCH(CH(CH₃)₂)CH₂O— C(O)CH₂OCH₃ 844. NHCH(CH(CH₃)₂)CH₂O— C(O)CH(CH₃)OH 845. NHCH(CH(CH₃)₂)CH₂O— C(O)CH(CH₃)OCH₃ 846. NHCH(CH(CH₃)₂)CH₂O— C(O)CH₂CH(CH₃)OH 847. NHCH(CH(CH₃)₂)CH₂O— C(O)CH(CH(CH₃)₂)OCH₃ 848. NHCH(CH(CH₃)₂)CH₂O— C(O)CH(CH₃)CH₂OH 849. NHCH(CH(CH₃)₂)CH₂O— C(O)CH(CH₃)CH₂OCH₃ 850. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)H 851. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH₃ 852. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH₂CH₃ 853. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CF₃ 854. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)(CH₂)₂CH₃ 855. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH₂OH 856. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH₂OCH₃ 857. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH(CH₃)OH 858. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH(CH₃)OCH₃ 859. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH₂CH(CH₃)OH 860. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH₂CH(CH₃)OCH₃ 861. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH(CH₃)CH₂OH 862. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)CH(CH₃)CH₂OCH₃ 863. NHCH₂CH₂OC(O)OCH₃ 864. NHCH₂CH₂OC(O)OCH₂CH₃ 865. NHCH₂CH₂OC(O)O(CH₂)₂CH₃ 866. NHCH₂CH₂OC(O)OCH(CH₃)OH 867. NHCH₂CH₂OC(O)OCH(CH₃)OCH₃ 868. NHCH₂CH₂O—C(O)OCH₂CH(CH₃)OH 869. NHCH₂CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 870. NHCH₂CH₂O—C(O)OCH(CH₃)CH₂OH 871. NHCH₂CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 872. NHCH₂CH₂CH₂OC(O)OCH₃ 873. NHCH₂CH₂CH₂OC(O)OCH₂CH₃ 874. NHCH₂CH₂CH₂O—C(O)O(CH₂)₂CH₃ 875. NHCH₂CH₂CH₂O—C(O)OCH(CH₃)OH 876. NHCH₂CH₂CH₂O— C(O)OCH(CH₃)OCH₃ 877. NHCH₂CH₂CH₂O— C(O)OCH₂CH(CH₃)OH 878. NHCH₂CH₂CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 879. NHCH₂CH₂CH₂O— C(O)OCH(CH₃)CH₂OH 880. NHCH₂CH₂CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 881. NHCH(CH₃)CH₂OC(O)OCH₃ 882. NHCH(CH₃)CH₂OC(O)OCH₂CH₃ 883. NHCH(CH₃)CH₂O—C(O)O(CH₂)₂CH₃ 884. NHCH(CH₃)CH₂O— C(O)OCH(CH₃)OH 885. NHCH(CH₃)CH₂O— C(O)OCH(CH₃)OCH₃ 886. NHCH(CH₃)CH₂O— C(O)OCH₂CH(CH₃)OH 887. NHCH(CH₃)CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 888. NHCH(CH₃)CH₂O— C(O)OCH(CH₃)CH₂OH 889. NHCH(CH₃)CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 890. NHCH(CH₃)CH₂CH₂O— C(O)OCH₃ 891. NHCH(CH₃)CH₂CH₂O— C(O)OCH₂CH₃ 892. NHCH(CH₃)CH₂CH₂O— C(O)O(CH₂)₂CH₃ 893. NHCH(CH₃)CH₂CH₂O— C(O)OCH(CH₃)OH 894. NHCH(CH₃)CH₂CH₂O— C(O)OCH(CH₃)OCH₃ 895. NHCH(CH₃)CH₂CH₂O— C(O)OCH₂CH(CH₃)OH 896. NHCH(CH₃)CH₂CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 897. NHCH(CH₃)CH₂CH₂O— C(O)OCH(CH₃)CH₂OH 898. NHCH(CH₃)CH₂CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 899. NHCH(CH₂CH₃)CH₂OC(O)OCH₃ 900. NHCH(CH₂CH₃)CH₂O— C(O)OCH₂CH₃ 901. NHCH(CH₂CH₃)CH₂O— C(O)O(CH₂)₂CH₃ 902. NHCH(CH₂CH₃)CH₂O— C(O)OCH(CH₃)OH 903. NHCH(CH₂CH₃)CH₂O— C(O)OCH(CH₃)OCH₃ 904. NHCH(CH₂CH₃)CH₂O— C(O)OCH₂CH(CH₃)OH 905. NHCH(CH₂CH₃)CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 906. NHCH(CH₂CH₃)CH₂O— C(O)OCH(CH₃)CH₂OH 907. NHCH(CH₂CH₃)CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 908. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH₃ 909. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH₂CH₃ 910. NHCH(CH₂CH₃)CH₂CH₂O— C(O)O(CH₂)₂CH₃ 911. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)OH 912. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)OCH₃ 913. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH₂CH(CH₃)OH 914. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 915. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)CH₂OH 916. NHCH(CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 917. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH₃ 918. NHCH(CH₂CH₂CH₃)CH₂O— C(C)OCH₂CH₃ 919. NHCH(CH₂CH₂CH₃)CH₂O— C(O)O(CH₂)₂CH₃ 920. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH₂OCH₃ 921. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH(CH₃)OH 922. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH(CH₃)OCH₃ 923. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH₂CH(CH₃)OH 924. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 925. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH(CH₃)CH₂OH 926. NHCH(CH₂CH₂CH₃)CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 927. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH₃ 928. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH₂CH₃ 929. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)O(CH₂)₂CH₃ 930. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)OH 931. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)OCH₃ 932. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH₂CH(CH₃)OH 933. NHCH(CH₂CH₂CH₃)O— C(O)OCH₂CH(CH₃)OCH₃ 934. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)CH₂OH 935. NHCH(CH₂CH₂CH₃)CH₂CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 936. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH₃ 937. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH₂CH₃ 938. NHCH(CH(CH₃)₂)CH₂O— C(O)O(CH₂)₂CH₃ 939. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH(CH₃)OCH₃ 940. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH₂CH(CH₃)OH 941. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH(CH(CH₃)₂)OCH₃ 942. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH(CH₃)CH₂OH 943. NHCH(CH(CH₃)₂)CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 944. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH₃ 945. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH₂CH₃ 946. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)O(CH₂)₂CH₃ 947. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH(CH₃)OCH₃ 948. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH₂CH(CH₃)OH 949. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH₂CH(CH₃)OCH₃ 950. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH(CH₃)CH₂OH 951. NHCH(CH(CH₃)₂)CH₂CH₂O— C(O)OCH(CH₃)CH₂OCH₃ 952. NHCH₂COOH 953. NHCH₂C(O)OCH₃ 954. NHCH₂C(O)OCH₂CH₃ 955. NHCH₂C(O)O(CH₂)₂CH₃ 956. NHCH₂C(O)OCH(CH₃)OH 957. NHCH₂C(O)OCH(CH₃)OCH₃ 958. NHCH₂C(O)OCH₂CH(CH₃)OH 959. NHCH₂C(O)OCH₂CH(CH₃)OCH₃ 960. NHCH₂C(O)OCH(CH₃)CH₂OH 961. NHCH₂C(O)OCH(CH₃)CH₂OCH₃ 962. NHCH₂C(O)NH₂ 963. NHCH₂C(O)NHOH 964. NHCH₂C(NH)NH₂ 965. NHCH₂C(O)NHCH₃ 966. NHCH₂C(O)NHCH₂CH₃ 967. NHCH₂C(O)NH(CH₂)₂CH₃ 968. NHCH₂C(O)NHCH(CH₃)OH 969. NHCH₂C(O)NHCH(CH₃)OCH₃ 970. NHCH₂C(O)NHCH₂CH(CH₃)OH 971. NHCH₂C(O)NHCH₂CH(CH₃)OCH₃ 972. NHCH₂C(O)NHCH(CH₃)CH₂OH 973. NHCH₂C(O)NHCH(CH₃)CH₂OCH₃ 974. NHCH₂C(O)N(CH₃)₂ 975. NHCH₂C(O)N(CH₂CH₃)₂ 976. NHCH(CH₃)COOH 977. NHCH(CH₃)C(O)OCH₃ 978. NHCH(CH₃)C(O)OCH₂CH₃ 979. NHCH(CH₃)C(O)O(CH₂)₂CH₃ 980. NHCH(CH₃)C(O)OCH(CH₃)OH 981. NHCH(CH₃)C(O)OCH(CH₃)OCH₃ 982. NHCH(CH₃)C(O)OCH₂CH(CH₃)OH 983. NHCH(CH₃)C(O)— OCH₂CH(CH₃)OCH₃ 984. NHCH(CH₃)C(O)OCH(CH₃)CH₂OH 985. NHCH(CH₃)C(O)— OCH(CH₃)CH₂OCH₃ 986. NHCH(CH₃)C(O)NH₂ 987. NHCH(CH₃)C(O)NHOH 988. NHCH(CH₃)C(NH)NH₂ 989. NHCH(CH₃)C(O)NHCH₃ 990. NHCH(CH₃)C(O)NHCH₂CH₃ 991. NHCH(CH₃)C(O)NH(CH₂)₂CH₃ 992. NHCH(CH₃)C(O)NHCH(CH₃)OH 993. NHCH(CH₃)C(O)NHCH(CH₃)OCH₃ 994. NHCH(CH₃)C(O)— NHCH₂CH(CH₃)OH 995. NHCH(CH₃)C(O)— NHCH₂CH(CH₃)OCH₃ 996. NHCH(CH₃)C(O)— NHCH(CH₃)CH₂OH 997. NHCH(CH₃)C(O)— NHCH(CH₃)CH₂OCH₃ 998. NHCH(CH₃)C(O)N(CH₃)₂ 999. NHCH(CH₃)C(O)N(CH₂CH₃)₂ 1000. NHCH₂CH₂COOH 1001. NHCH₂CH₂C(O)OCH₃ 1002. NHCH₂CH₂C(O)OCH₂CH₃ 1003. NHCH₂CH₂C(O)O(CH₂)₂CH₃ 1004. NHCH₂CH₂C(O)OCH(CH₃)OH 1005. NHCH₂CH₂C(O)OCH(CH₃)OCH₃ 1006. NHCH₂CH₂C(O)OCH₂CH(CH₃)OH 1007. NHCH₂CH₂C(O)— OCH₂CH(CH₃)OCH₃ 1008. NHCH₂CH₂C(O)OCH(CH₃)CH₂OH 1009. NHCH₂CH₂C(O)— OCH(CH₃)CH₂OCH₃ 1010. NHCH₂CH₂C(O)NH₂ 1011. NHCH₂CH₂C(O)NHOH 1012. NHCH₂CH₂C(NH)NH₂ 1013. NHCH₂CH₂C(O)NHCH₃ 1014. NHCH₂CH₂C(O)NHCH₂CH₃ 1015. NHCH₂CH₂C(O)NH(CH₂)₂CH₃ 1016. NHCH₂CH₂C(O)NHCH(CH₃)OH 1017. NHCH₂CH₂C(O)NHCH(CH₃)OCH₃ 1018. NHCH₂CH₂C(O)—NHCH₂CH(CH₃)OH 1019. NHCH₂CH₂C(O)— NHCH₂CH(CH₃)OCH₃ 1020. NHCH₂CH₂C(O)—NHCH(CH₃)CH₂OH 1021. NHCH₂CH₂C(O)— NHCH(CH₃)CH₂OCH₃ 1022. NHCH₂CH₂C(O)N(CH₃)₂ 1023. NHCH₂CH₂C(O)N(CH₂CH₃)₂ 1024. NHCH₂OCH₃ 1025. NHCH₂OCH₂CH₃ 1026. NHCH₂O(CH₂)₂CH₃ 1027. NHCH₂OCH(CH₃)₂ 1028. NHCH₂OCH₂OCH₃ 1029. NHCH₂CH₂OH 1030. NHCH₂CH₂OCH₃ 1031. NHCH₂CH₂OCH₂CH₃ 1032. NHCH₂CH₂O(CH₂)₂CH₃ 1033. NHCH₂CH₂OCH(CH₃)₂ 1034. NHCH₂CH₂OCH₂OCH₃ 1035. NHCH₂CH₂CH₂OH 1036. NHCH₂CH₂CH₂OCH₃ 1037. NHCH₂CH₂CH₂OCH₂CH₃ 1038. NHCH₂CH₂CH₂O(CH₂)₂CH₃ 1039. NHCH₂CH₂CH₂OCH(CH₃)₂ 1040. NHCH₂CH₂CH₂OCH₂OCH₃ 1041. NHCH(CH₃)OCH₃ 1042. NHCH(CH₃)OCH₂CH₃ 1043. NHCH(CH₃)O(CH₂)₂CH₃ 1044. NHCH(CH₃)OCH(CH₃)₂ 1045. NHCH(CH₃)OCH₂OCH₃ 1046. NHC[(CH₃)₂]OCH₃ 1047. NHC[(CH₃)₂]PCH₂CH₃ 1048. NHC[(CH₃)₂]O(CH₂)₂CH₃ 1049. NHC[(CH₃)₂]OCH(CH₃)₂ 1050. NHC[(CH₃)₂]OCH₂OCH₃ 1051. NHCH(CH₂CH₃)OCH₃ 1052. NHCH(CH₂CH₃)OCH₂CH₃ 1053. NHCH(CH₂CH₃)O(CH₂)₂CH₃ 1054. NHCH(CH₂CH₃)OCH(CH₃)₂ 1055. NHCH(CH₂CH₃)OCH₂OCH₃ 1056. NHCH(CH₂CH)OCH₃ 1057. NHCH(CH₂CH)OCH₂CH₃ 1058. NHCH(CH₂CH)O(CH₂)₂CH₃ 1059. NHCH(CH₂CH)OCH(CH₃)₂ 1060. NHCH(CH₂CH)OCH₂OCH₃ 1061. NHCH(CH₂OCH₃)OCH₃ 1062. NHCH(CH₂OCH₃)OCH₂CH₃ 1063. NHCH(CH₂OCH₃)O(CH₂)₂CH₃ 1064. NHCH(CH₂OCH₃)OCH(CH₃)₂ 1065. NHCH(CH₂OCH₃)OCH₂OCH₃ 1066. NHCH[CH(CH₃)₂]OCH₃ 1067. NHCH[CH(CH₃)₂]OCH₂CH₃ 1068. NHCH[CH(CH₃)₂]O(CH₂)₂CH₃ 1069. NHCH{CH(CH₃)₂]OCH(CH₃)₂ 1070. NHCH[CH(CH₃)₂]OCH₂OCH₃ 1071. NHCH(CH(CH₂CH₃)CH₃)OCH₃ 1072. NHCH(CH(CH₂CH₃)CH₃)—OCH₂CH₃ 1073. NHCH(CH(CH₂CH₃)CH₃)— O(CH₂)₂CH₃ 1074. NHCH(CH(CH₂CH₃)CH₃)— OCH(CH₃)₂ 1075. NHCH(CH(CH₂CH₃)CH₃)— OCH₂OCH₃ 1076. NHCH(CH₂CH₂CH₃)OCH₃ 1077. NHCH(CH₂CH₂CH₃)OCH₂CH₃ 1078. NHCH(CH₂CH₂CH₃)O(CH₂)₂CH₃ 1079. NHCH(CH₂CH₂CH₃)OCH(CH₃)₂ 1080. NHCH(CH₂CH₂CH₃)OCH₂OCH₃ 1081. NHCH(CH₃)CH₂OH 1082. NHCH(CH₃)CH₂OCH₃ 1083. NHCH(CH₃)CH₂OCH₂CH₃ 1084. NHCH(CH₃)CH₂O(CH₂)₂CH₃ 1085. NHCH(CH₃)CH₂OCH(CH₃)₂ 1086. NHCH(CH₃)CH₂OCH₂OCH₃ 1087. NHCH(CH₂CH₃)CH₂OH 1088. NHCH(CH₂CH₃)CH₂OCH₃ 1089. NHCH(CH₂CH₃)CH₂OCH₂CH₃ 1090. NHCH(CH₂CH₃)CH₂O(CH₂)₂CH₃ 1091. NHCH(CH₂CH₃)CH₂OCH(CH₃)₂ 1092. NHCH(CH₂CH₃)CH₂OCH₂OCH₃ 1093. NHC[(CH₃)₂]CH₂OH 1094. NHC[(CH₃)₂]CH₂OCH₃ 1095. NHC[(CH₃)₂]CH₂OCH₂CH₃ 1096. NHC[(CH₃)₂]CH₂O(CH₂)₂CH₃ 1097. NHC[(CH₃)₂]CH₂OCH(CH₃)₂ 1098. NHC[(CH₃)₂]CH₂OCH₂OCH₃ 1099. NHCH(CH₂CH)CH₂OH 1100. NHCH(CH₂CH)CH₂OCH₃ 1101. NHCH(CH₂CH)CH₂OCH₂CH₃ 1102. NHCH(CH₂CH)CH₂O(CH₂)₂CH₃ 1103. NHCH(CH₂CH)CH₂OCH(CH₃)₂ 1104. NHCH(CH₂CH)CH₂OCH₂OCH₃ 1105. NHCH(CH₂OCH₃)CH₂OH 1106. NHCH(CH₂OCH₃)CH₂OCH₃ 1107. NHCH(CH₂OCH₃)CH₂OCH₂CH₃ 1108. NHCH(CH₂OCH₃)CH₂O—(CH₂)₂CH₃ 1109. NHCH(CH₂OCH₃)CH₂OCH(CH₃)₂ 1110. NHCH(CH₂OCH₃)CH₂OCH₂OCH₃ 1111. NHCH₂CH(CH₃)OH 1112. NHCH₂CH(CH₃)OCH₃ 1113. NHCH₂CH(CH₃)OCH₂CH₃ 1114. NHCH₂CH(CH₃)O(CH₂)₂CH₃ 1115. NHCH₂CH(CH₃)OCH(CH₃)₂ 1116. NHCH₂CH(CH₃)OCH₂OCH₃ 1117. NHCH₂CH(CH₂CH₃)OH 1118. NHCH₂CH(CH₂CH₃)OCH₃ 1119. NHCH₂CH(CH₂CH₃)OCH₂CH₃ 1120. NHCH₂CH(CH₂CH₃)O(CH₂)₂CH₃ 1121. NHCH₂CH(CH₂CH₃)OCH(CH₃)₂ 1122. NHCH₂CH(CH₂CH₃)OCH₂OCH₃ 1123. NHCH₂CH(CH₂CH)OH 1124. NHCH₂CH(CH₂CH)OCH₃ 1125. NHCH₂CH(CH₂CH)OCH₂CH₃ 1126. NHCH₂C(CH₂CH)(CH₂CH)O— (CH₂)₂CH₃ 1127. NHCH₂CH(CH₂CH)OCH(CH₃)₂ 1128. NHCH₂CH(CH₂CH)OCH₂OCH₃ 1129. NHCH₂CH(CH₂OCH₃)OH 1130. NHCH₂CH(CH₂OCH₃)OCH₃ 1131. NHCH₂CH(CH₂OCH₃)OCH₂CH₃ 1132. NHCH₂CH(CH₂OCH₃)O— (CH₂)₂CH₃ 1133. NHCH₂CH(CH₂OCH₃)OCH(CH₃)₂ 1134. NHCH₂CH(CH₂OCH₃)OCH₂OCH₃ 1135. NHCH(CH₃)CH₂CH₂OH 1136. NHCH(CH₃)CH₂CH₂OCH₃ 1137. NHCH(CH₃)CH₂CH₂OCH₂CH₃ 1138. NHCH(CH₃)CH₂CH₂O(CH₂)₂CH₃ 1139. NHCH(CH₃)CH₂CH₂OCH(CH₃)₂ 1140. NHCH(CH₃)CH₂CH₂OCH₂OCH₃ 1141. NHCH(CH₂CH₃)CH₂CH₂OH 1142. NHCH(CH₂CH₃)CH₂CH₂OCH₃ 1143. NHCH(CH₂CH₃)CH₂CH₂O–CH₂CH₃ 1144. NHCH(CH₂CH₃)CH₂CH₂O— (CH₂)₂CH₃ 1145. NHCH(CH₂CH₃)CH₂CH₂O—CH(CH₃)₂ 1146. NHCH(CH₂CH₃)CH₂CH₂O—CH₂OCH₃ 1147. NHC[(CH₃)₂]CH₂CH₂OH 1148. NHC[(CH₃)₂]CH₂CH₂OCH₃ 1149. NHC[(CH₃)₂]CH₂CH₂OCH₂CH₃ 1150. NHC[(CH₃)₂]CH₂CH₂O(CH₂)₂CH₃ 1151. NHC[(CH₃)₂]CH₂CH₂OCH(CH₃)₂ 1152. NHC[(CH₃)₂]CH₂CH₂OCH₂OCH₃ 1153. NHCH(CH₂CH)CH₂CH₂OH 1154. NHCH(CH₂CH)CH₂CH₂OCH₃ 1155. NHCH(CH₂CH)CH₂CH₂OCH₂CH₃ 1156. NHCH(CH₂CH)CH₂CH₂O—(CH₂)₂CH₃ 1157. NHCH(CH₂CH)CH₂CH₂O—CH(CH₃)₂ 1158. NHCH(CH₂CH)CH₂CH₂O—CH₂OCH₃ 1159. NHCH(CH₂OCH₃)CH₂CH₂OH 1160. NHCH(CH₂OCH₃)CH₂CH₂OCH₃ 1161. NHCH(CH₂OCH₃)CH₂CH₂O—CH₂CH₃ 1162. NHCH(CH₂OCH₃)CH₂CH₂O— (CH₂)₂CH₃ 1163. NHCH(CH₂OCH₃)CH₂CH₂O— CH(CH₃)₂ 1164. NHCH(CH₂OCH₃)CH₂CH₂O— CH₂OCH₃ 1165. NHCH(CH₃)CH(CH₃)OH 1166. NHCH(CH₃)CH(CH₃)OCH₃ 1167. NHCH(CH₃)CH(CH₃)OCH₂CH₃ 1168. NHCH(CH₃)CH(CH₃)O(CH₂)₂CH₃ 1169. NHCH(CH₃)CH(CH₃)OCH(CH₃)₂ 1170. NHCH(CH₃)CH(CH₃)OCH₂OCH₃ 1171. NHCH(CH₂CH₃)CH(CH₃)OH 1172. NHCH(CH₂CH₃)CH(CH₃)OCH₃ 1173. NHCH(CH₂CH₃)CH(CH₃)O—CH₂CH₃ 1174. NHCH(CH₂CH₃)CH(CH₃)O— (CH₂)₂CH₃ 1175. NHCH(CH₂CH₃)CH(CH₃)O— CH(CH₃)₂ 1176. NHCH(CH₂CH₃)CH(CH₃)O— CH₂OCH₃ 1177. NHC[(CH₃)₂)CH(CH₃)OH 1178. NHC[(CH₃)₂]CH(CH₃)OCH₃ 1179. NHC[(CH₃)₂]CH(CH₃)OCH₂CH₃ 1180. NHC[(CH₃)₂]CH(CH₃)O(CH₂)₂CH₃ 1181. NHC[(CH₃)₂]CH(CH₃)OCH(CH₃)₂ 1182. NHC[(CH₃)₂]CH(CH₃)OCH₂OCH₃ 1183. NHCH(CH₂CH)CH(CH₃)OH 1184. NHCH(CH₂CH)CH(CH₃)OCH₃ 1185. NHCH(CH₂CH)CH(CH₃)OCH₂CH₃ 1186. NHCH(CH₂CH)CH(CH₃)O— (CH₂)₂CH₃ 1187. NHCH(CH₂CH)CH(CH₃)O—CH(CH₃)₂ 1188. NHCH(CH₂CH)CH(CH₃)O—CH₂OCH₃ 1189. NHCH(CH₂OCH₃)CH(CH₃)OH 1190. NHCH(CH₂OCH₃)CH(CH₃)OCH₃ 1191. NHCH(CH₂OCH₃)CH(CH₃)O— CH₂CH₃ 1192. NHCH(CH₂OCH₃)CH(CH₃)O— (CH₂)₂CH₃ 1193. NHCH(CH₂OCH₃)CH(CH₃)O— CH(CH₃)₂ 1194. NHCH(CH₂OCH₃)CH(CH₃)O— CH₂OCH₃ 1195. N(CH₃)CH₂OCH₃ 1196. N(CH₃)CH₂OCH₂CH₃ 1197. N(CH₃)CH₂O(CH₂)₂CH₃ 1198. N(CH₃)CH₂OCH(CH₃)₂ 1199. N(CH₃)CH₂OCH₂OCH₃ 1200. N(CH₃)CH₂CH₂OH 1201. N(CH₃)CH₂CH₂OCH₃ 1202. N(CH₃)CH₂CH₂OCH₂CH₃ 1203. N(CH₃)CH₂CH₂O(CH₂)₂CH₃ 1204. N(CH₃)CH₂CH₂OCH(CH₃)₂ 1205. N(CH₃)CH₂CH₂OCH₂OCH₃ 1206. N(CH₃)CH₂CH₂CH₂OH 1207. N(CH₃)CH₂CH₂CH₂OCH₃ 1208. N(CH₃)CH₂CH₂CH₂OCH₂CH₃ 1209. N(CH₃)CH₂CH₂CH₂O(CH₂)₂CH₃ 1210. N(CH₃)CH₂CH₂CH₂OCH(CH₃)₂ 1211. N(CH₃)CH₂CH₂CH₂OCH₂OCH₃ 1212. N(CH₃)CH(CH₃)OCH₃ 1213. N(CH₃)CH(CH₃)OCH₂CH₃ 1214. N(CH₃)CH(CH₃)O(CH₂)₂CH₃ 1215. N(CH₃)CH(CH₃)OCH(CH₃)₂ 1216. N(CH₃)CH(CH₃)OCH₂OCH₃ 1217. N(CH₃)CH(CH₂CH)O(CH₂)₂CH₃ 1218. N(CH₃)CH(CH₂CH)OCH(CH₃)₂ 1219. N(CH₃)CH(CH₂CH)OCH₂OCH₃ 1220. N(CH₃)CH(CH₂OCH₃)OCH₃ 1221. N(CH₃)CH(CH₂OCH₃)OCH₂CH₃ 1222. N(CH₃)CH(CH₂OCH₃)O—(CH₂)₂CH₃ 1223. N(CH₃)CH(CH₂OCH₃)OCH(CH₃)₂ 1224. N(CH₃)CH(CH₂OCH₃)OCH₂OCH₃ 1225. N(CH₃)CH(CH₃)CH₂OH 1226. N(CH₃)CH(CH₃)CH₂OCH₃ 1227. N(CH₃)CH(CH₃)CH₂OCH₂CH₃ 1228. N(CH₃)CH(CH₃)CH₂O(CH₂)₂CH₃ 1229. N(CH₃)CH(CH₃)CH₂OCH(CH₃)₂ 1230. N(CH₃)CH(CH₃)CH₂OCH₂OCH₃ 1231. N(CH₃)CH(CH₂CH₃)CH₂OH 1232. N(CH₃)CH(CH₂CH₃)CH₂OCH₃ 1233. N(CH₃)CH(CH₂CH₃)CH₂OCH₂CH₃ 1234. N(CH₃)CH(CH₂CH₃)CH₂O— (CH₂)₂CH₃ 1235. N(CH₃)CH(CH₂CH₃)CH₂O—CH(CH₃)₂ 1236. N(CH₃)CH(CH₂CH₃)CH₂O—CH₂OCH₃ 1237. N(CH₃)CH(CH₂CH)CH₂OH 1238. N(CH₃)CH(CH₂CH)CH₂OCH₃ 1239. N(CH₃)CH(CH₂CH)CH₂OCH₂CH₃ 1240. N(CH₃)CH(CH₂CH)CH₂O—(CH₂)₂CH₃ 1241. N(CH₃)CH(CH₂CH)CH₂O—CH(CH₃)₂ 1242. N(CH₃)CH(CH₂CH)CH₂O—CH₂OCH₃ 1243. N(CH₃)CH(CH₂OCH₃)CH₂OH 1244. N(CH₃)CH(CH₂OCH₃)CH₂OCH₃ 1245. N(CH₃)CH(CH₂OCH₃)CH₂O—CH₂CH₃ 1246. N(CH₃)CH(CH₂OCH₃)CH₂O— (CH₂)₂CH₃ 1247. N(CH₃)CH(CH₂OCH₃)CH₂O— CH(CH₃)₂ 1248. N(CH₃)CH(CH₂OCH₃)CH₂O— CH₂OCH₃ 1249. N(CH₃)CH₂CH(CH₃)OH 1250. N(CH₃)CH₂CH(CH₃)OCH₃ 1251. N(CH₃)CH₂CH(CH₃)OCH₂CH₃ 1252. N(CH₃)CH₂CH(CH₃)O(CH₂)₂CH₃ 1253. N(CH₃)CH₂CH(CH₃)OCH(CH₃)₂ 1254. N(CH₃)CH₂CH(CH₃)OCH₂OCH₃ 1255. N(CH₃)CH₂CH(CH₂CH₃)OH 1256. N(CH₃)CH₂CH(CH₂CH₃)OCH₃ 1257. N(CH₃)CH₂CH(CH₂CH₃)OCH₂CH₃ 1258. N(CH₃)CH₂CH(CH₂CH₃)O— (CH₂)₂CH₃ 1259. N(CH₃)CH₂CH(CH₂CH₃)O—CH(CH₃)₂ 1260. N(CH₃)CH₂CH(CH₂CH₃)O—CH₂OCH₃ 1261. N(CH₃)CH₂CH(CH₂CH)OH 1262. N(CH₃)CH₂CH(CH₂CH)OCH₃ 1263. N(CH₃)CH₂CH(CH₂CH)OCH₂CH₃ 1264. N(CH₃)CH₂CH(CH₂CH)(CH₂CH)— O(CH₂)₂CH₃ 1265. N(CH₃)CH₂CH(CH₂CH)—OCH(CH₃)₂ 1266. N(CH₃)CH₂CH(CH₂CH)O—CH₂OCH₃ 1267. N(CH₃)CH₂CH(CH₂OCH₃)OH 1268. N(CH₃)CH₂CH(CH₂OCH₃)OCH₃ 1269. N(CH₃)CH₂CH(CH₂OCH₃)O—CH₂CH₃ 1270. N(CH₃)CH₂CH(CH₂OCH₃)O— (CH₂)₂CH₃ 1271. N(CH₃)CH₂CH(CH₂OCH₃)O— CH(CH₃)₂ 1272. N(CH₃)CH₂CH(CH₂OCH₃)O— CH₂OCH₃ 1273. N(CH₃)CH(CH₃)CH₂CH₂OH 1274. N(CH₃)CH(CH₃)CH₂CH₂OCH₃ 1275. N(CH₃)CH(CH₃)CH₂CH₂OCH₂CH₃ 1276. N(CH₃)CH(CH₃)CH₂CH₂O— (CH₂)₂CH₃ 1277. N(CH₃)CH(CH₃)CH₂CH₂O—CH(CH₃)₂ 1278. N(CH₃)CH(CH₃)CH₂CH₂O—CH₂OCH₃ 1279. N(CH₃)CH(CH₂CH₃)CH₂CH₂OH 1280. N(CH₃)CH(CH₂CH₃)CH₂CH₂OCH₃ 1281. N(CH₃)CH(CH₂CH₃)CH₂CH₂O— CH₂CH₃ 1282. N(CH₃)CH(CH₂CH₃)CH₂CH₂O— (CH₂)₂CH₃ 1283. N(CH₃)CH(CH₂CH₃)CH₂CH₂O— CH(CH₃)₂ 1284. N(CH₃)CH(CH₂CH₃)CH₂CH₂O— CH₂OCH₃ 1285. N(CH₃)C[(CH₃)₂]CH₂CH₂OH 1286. N(CH₃)C[(CH₃)₂]CH₂CH₂OCH₃ 1287. N(CH₃)C[(CH₃)₂]CH₂CH₂O—CH₂CH₃ 1288. N(CH₃)C[(CH₃)₂]CH₂CH₂O— (CH₂)₂CH₃ 1289. N(CH₃)C[(CH₃)₂]CH₂CH₂O—CH(CH₃)₂ 1290. N(CH₃)C[(CH₃)₂]CH₂CH₂O— CH₂OCH₃ 1291. N(CH₃)CH(CH₂CH)CH₂CH₂OH 1292. N(CH₃)CH(CH₂CH)CH₂CH₂OCH₃ 1293. N(CH₃)CH(CH₂CH)— CH₂CH₂OCH₂CH₃ 1294. N(CH₃)CH(CH₂CH)CH₂CH₂O— (CH₂)₂CH₃ 1295. N(CH₃)CH(CH₂CH)CH₂CH₂O— CH(CH₃)₂ 1296. N(CH₃)CH(CH₂CH)CH₂CH₂O— CH₂OCH₃ 1297. N(CH₃)CH(CH₂OCH₃)CH₂CH₂OH 1298. N(CH₃)CH(CH₂OCH₃)—CH₂CH₂OCH₃ 1299. N(CH₃)CH(CH₂OCH₃)CH₂CH₂O— CH₂CH₃ 1300. N(CH₃)CH(CH₂OCH₃)CH₂CH₂O— (CH₂)₂CH₃ 1301. N(CH₃)CH(CH₂OCH₃)CH₂CH₂O— CH(CH₃)₂ 1302. N(CH₃)CH(CH₂OCH₃)CH₂CH₂O— CH₂OCH₃ 1303. N(CH₂CH₃)CH₂OCH₃ 1304. N(CH₂CH₃)CH₂OCH₂CH₃ 1305. N(CH₂CH₃)CH₂O(CH₂)₂CH₃ 1306. N(CH₂CH₃)CH₂OCH(CH₃)₂ 1307. N(CH₂CH₃)CH₂OCH₂OCH₃ 1308. N(CH₂CH₃)CH₂CH₂OH 1309. N(CH₂CH₃)CH₂CH₂OCH₃ 1310. N(CH₂CH₃)CH₂CH₂OCH₂CH₃ 1311. N(CH₂CH₃)CH₂CH₂O(CH₂)₂CH₃ 1312. N(CH₂CH₃)CH₂CH₂OCH(CH₃)₂ 1313. N(CH₂CH₃)CH₂CH₂OCH₂OCH₃ 1314. N(CH₂CH₃)CH₂CH₂CH₂OH 1315. N(CH₂CH₃)CH₂CH₂CH₂OCH₃ 1316. N(CH₂CH₃)CH₂CH₂CH₂OCH₂CH₃ 1317. N(CH₂CH₃)CH₂CH₂CH₂O—(CH₂)₂CH₃ 1318. N(CH₂CH₃)CH₂CH₂CH₂O—CH(CH₃)₂ 1319. N(CH₂CH₃)CH₂CH₂CH₂O—CH₂OCH₃ 1320. N(CH₂CH₃)CH(CH₃)OCH₃ 1321. N(CH₂CH₃)CH(CH₃)OCH₂CH₃ 1322. N(CH₂CH₃)CH(CH₃)O(CH₂)₂CH₃ 1323. N(CH₂CH₃)CH(CH₃)OCH(CH₃)₂ 1324. N(CH₂CH₃)CH(CH₃)OCH₂OCH₃ 1325. N(CH₂CH₃)CH(CH₂CH)O—(CH₂)₂CH₃ 1326. N(CH₂CH₃)CH(CH₂CH)O—CH(CH₃)₂ 1327. N(CH₂CH₃)CH(CH₂CH)O—CH₂OCH₃ 1328. N(CH₂CH₃)CH(CH₂OCH₃)OCH₃ 1329. N(CH₂CH₃)CH(CH₂OCH₃)O—CH₂CH₃ 1330. N(CH₂CH₃)CH(CH₂OCH₃)O— (CH₂)₂CH₃ 1331. N(CH₂CH₃)CH(CH₂OCH₃)O— CH(CH₃)₂ 1332. N(CH₂CH₃)CH(CH₂OCH₃)O— CH₂OCH₃ 1333. N(CH₂CH₃)CH(CH₃)CH₂OH 1334. N(CH₂CH₃)CH(CH₃)CH₂OCH₃ 1335. N(CH₂CH₃)CH(CH₃)CH₂OCH₂CH₃ 1336. N(CH₂CH₃)CH(CH₃)CH₂O— (CH₂)₂CH₃ 1337. N(CH₂CH₃)CH(CH₃)CH₂O—CH(CH₃)₂ 1338. N(CH₂CH₃)CH(CH₃)CH₂O—CH₂OCH₃ 1339. N(CH₂CH₃)CH(CH₂CH₃)CH₂OH 1340. N(CH₂CH₃)CH(CH₂CH₃)CH₂OCH₃ 1341. N(CH₂CH₃)CH(CH₂CH₃)CH₂O— CH₂CH₃ 1342. N(CH₂CH₃)CH(CH₂CH₃)CH₂O— (CH₂)₂CH₃ 1343. N(CH₂CH₃)CH(CH₂CH₃)CH₂O— CH(CH₃)₂ 1344. N(CH₂CH₃)CH(CH₂CH₃)CH₂O— CH₂OCH₃ 1345. N(CH₂CH₃)CH(CH₂CH)CH₂OH 1346. N(CH₂CH₃)CH(CH₂CH)CH₂OCH₃ 1347. N(CH₂CH₃)CH(CH₂CH)CH₂O— CH₂CH₃ 1348. N(CH₂CH₃)CH(CH₂CH)CH₂O— (CH₂)₂CH₃ 1349. N(CH₂CH₃)CH(CH₂CH)CH₂O— CH(CH₃)₂ 1350. N(CH₂CH₃)CH(CH₂CH)CH₂O— CH₂OCH₃ 1351. N(CH₂CH₃)CH(CH₂OCH₃)CH₂OH 1352. N(CH₂CH₃)CH(CH₂OCH₃)CH₂O—CH₃ 1353. N(CH₂CH₃)CH(CH₂OCH₃)CH₂O— CH₂CH₃ 1354. N(CH₂CH₃)CH(CH₂OCH₃)CH₂O— (CH₂)₂CH₃ 1355. N(CH₂CH₃)CH(CH₂OCH₃)CH₂O— CH(CH₃)₂ 1356. N(CH₂CH₃)CH(CH₂OCH₃)CH₂O— CH₂OCH₃ 1357. N(CH₂CH₃)CH₂CH(CH₃)OH 1358. N(CH₂CH₃)CH₂CH(CH₃)OCH₃ 1359. N(CH₂CH₃)CH₂CH(CH₃)OCH₂CH₃ 1360. N(CH₂CH₃)CH₂CH(CH₃)O— (CH₂)₂CH₃ 1361. N(CH₂CH₃)CH₂CH(CH₃)O—CH(CH₃)₂ 1362. N(CH₂CH₃)CH₂CH(CH₃)O—CH₂OCH₃ 1363. N(CH₂CH₃)CH₂CH(CH₂CH₃)OH 1364. N(CH₂CH₃)CH₂CH(CH₂CH₃)OCH₃ 1365. N(CH₂CH₃)CH₂CH(CH₂CH₃)O— CH₂CH₃ 1366. N(CH₂CH₃)CH₂CH(CH₂CH₃)O— (CH₂)₂CH₃ 1367. N(CH₂CH₃)CH₂CH(CH₂CH₃)O— CH(CH₃)₂ 1368. N(CH₂CH₃)CH₂CH(CH₂CH₃)O— CH₂OCH₃ 1369. N(CH₂CH₃)CH₂CH(CH₂CH)OH 1370. N(CH₂CH₃)CH₂CH(CH₂CH)OCH₃ 1371. N(CH₂CH₃)CH₂CH(CH₂CH)O— CH₂CH₃ 1372. N(CH₂CH₃)CH₂C(CH₂CH)(CH₂CH)O— (CH₂)₂CH₃ 1373. N(CH₂CH₃)CH₂CH(CH₂CH)— OCH(CH₃)₂ 1374. N(CH₂CH₃)CH₂CH(CH₂CH)O— CH₂OCH₃ 1375. N(CH₂CH₃)CH₂CH(CH₂OCH₃)OH 1376. N(CH₂CH₃)CH₂CH(CH₂OCH₃)O—CH₃ 1377. N(CH₂CH₃)CH₂CH(CH₂OCH₃)O— CH₂CH₃ 1378. N(CH₂CH₃)CH₂CH(CH₂OCH₃)O— (CH₂)₂CH₃ 1379. N(CH₂CH₃)CH₂CH(CH₂OCH₃)O— CH(CH₃)₂ 1380. N(CH₂CH₃)CH₂CH(CH₂OCH₃)O— CH₂OCH₃ 1381. N(CH₂CH₃)CH(CH₃)CH₂CH₂OH 1382. N(CH₂CH₃)CH(CH₃)CH₂CH₂OCH₃ 1383. N(CH₂CH₃)CH(CH₃)CH₂CH₂O— CH₂CH₃ 1384. N(CH₂CH₃)CH(CH₃)CH₂CH₂O— (CH₂)₂CH₃ 1385. N(CH₂CH₃)CH(CH₃)CH₂CH₂O— CH(CH₃)₂ 1386. N(CH₂CH₃)CH(CH₃)CH₂CH₂O— CH₂OCH₃ 1387. N(CH₂CH₃)CH(CH₂CH₃)—CH₂CH₂OH 1388. N(CH₂CH₃)CH(CH₂CH₃)— CH₂CH₂OCH₃ 1389. N(CH₂CH₃)CH(CH₂CH₃)— CH₂CH₂OCH₂CH₃ 1390. N(CH₂CH₃)CH(CH₂CH₃)— CH₂CH₂O(CH₂)₂CH₃ 1391. N(CH₂CH₃)CH(CH₂CH₃)— CH₂CH₂OCH(CH₃)₂ 1392. N(CH₂CH₃)CH(CH₂CH₃)— CH₂CH₂OCH₂OCH₃ 1393. N(CH₂CH₃)C[(CH₃)₂)CH₂CH₂OH 1394. N(CH₂CH₃)C[(CH₃)₂)—CH₂CH₂OCH₃ 1395. N(CH₂CH₃)C[(CH₃)₂]CH₂CH₂O— CH₂CH₃ 1396. N(CH₂CH₃)C[(CH₃)₂]CH₂CH₂O— (CH₂)₂CH₃ 1397. N(CH₂CH₃)C[(CH₃)₂]CH₂CH₂O— CH(CH₃)₂ 1398. N(CH₂CH₃)C[(CH₃)₂]CH₂CH₂O— CH₂OCH₃ 1399. N(CH₂CH₃)CH(CH₂CH)—CH₂CH₂OH 1400. N(CH₂CH₃)CH(CH₂CH)— CH₂CH₂OCH₃ 1401. N(CH₂CH₃)CH(CH₂CH)— CH₂CH₂OCH₂CH₃ 1402. N(CH₂CH₃)CH(CH₂CH)— CH₂CH₂O(CH₂)₂CH₃ 1403. N(CH₂CH₃)CH(CH₂CH)— CH₂CH₂OCH(CH₃)₂ 1404. N(CH₂CH₃)CH(CH₂CH)— CH₂CH₂OCH₂OCH₃ 1405. N(CH₂CH₃)CH(CH₂OCH₃)— CH₂CH₂OH 1406. N(CH₂CH₃)CH(CH₂OCH₃)— CH₂CH₂OCH₃ 1407. N(CH₂CH₃)CH(CH₂OCH₃)— CH₂CH₂OCH₂CH₃ 1408. N(CH₂CH₃)CH(CH₂OCH₃)— CH₂CH₂O(CH₂)₂CH₃ 1409. N(CH₂CH₃)CH(CH₂OCH₃)— CH₂CH₂OCH(CH₃)₂ 1410. N(CH₂CH₃)CH(CH₂OCH₃)— CH₂CH₂OCH₂OCH₃ 1411. N(CH₂OCH₃)CH₂OCH₃ 1412. N(CH₂OCH₃)CH₂OCH₂CH₃ 1413. N(CH₂OCH₃)CH₂O(CH₂)₂CH₃ 1414. N(CH₂OCH₃)CH₂OCH(CH₃)₂ 1415. N(CH₂OCH₃)CH₂OCH₂OCH₃ 1416. N(CH₂OCH₃)CH₂CH₂OH 1417. N(CH₂OCH₃)CH₂CH₂OCH₃ 1418. N(CH₂OCH₃)CH₂CH₂OCH₂CH₃ 1419. N(CH₂OCH₃)CH₂CH₂O(CH₂)₂CH₃ 1420. N(CH₂OCH₃)CH₂CH₂OCH(CH₃)₂ 1421. N(CH₂OCH₃)CH₂CH₂OCH₂OCH₃ 1422. N(CH₂OCH₃)CH₂CH₂CH₂OH 1423. N(CH₂OCH₃)CH₂CH₂CH₂OCH₃ 1424. N(CH₂OCH₃)CH₂CH₂CH₂O—CH₂CH₃ 1425. N(CH₂OCH₃)CH₂CH₂CH₂O— (CH₂)₂CH₃ 1426. N(CH₂OCH₃)CH₂CH₂CH₂O— CH(CH₃)₂ 1427. N(CH₂OCH₃)CH₂CH₂CH₂O— CH₂OCH₃ 1428. N(CH₂OCH₃)CH(CH₃)OCH₃ 1429. N(CH₂OCH₃)CH(CH₃)OCH₂CH₃ 1430. N(CH₂OCH₃)CH(CH₃)O—(CH₂)₂CH₃ 1431. N(CH₂OCH₃)CH(CH₃)OCH(CH₃)₂ 1432. N(CH₂OCH₃)CH(CH₃)OCH₂OCH₃ 1433. N(CH₂OCH₃)CH(CH₂CH)O— (CH₂)₂CH₃ 1434. N(CH₂OCH₃)CH(CH₂CH)O— CH(CH₃)₂ 1435. N(CH₂OCH₃)CH(CH₂CH)O— CH₂OCH₃ 1436. N(CH₂OCH₃)CH(CH₂OCH₃)OCH₃ 1437. N(CH₂OCH₃)CH(CH₂OCH₃)O— CH₂CH₃ 1438. N(CH₂OCH₃)CH(CH₂OCH₃)O— (CH₂)₂CH₃ 1439. N(CH₂OCH₃)CH(CH₂OCH₃)O— CH(CH₃)₂ 1440. N(CH₂OCH₃)CH(CH₂OCH₃)O— CH₂OCH₃ 1441. N(CH₂OCH₃)CH(CH₃)CH₂OH 1442. N(CH₂OCH₃)CH(CH₃)CH₂OCH₃ 1443. N(CH₂OCH₃)CH(CH₃)CH₂O—CH₂CH₃ 1444. N(CH₂OCH₃)CH(CH₃)CH₂O— (CH₂)₂CH₃ 1445. N(CH₂OCH₃)CH(CH₃)CH₂O— CH(CH₃)₂ 1446. N(CH₂OCH₃)CH(CH₃)CH₂O— CH₂OCH₃ 1447. N(CH₂OCH₃)CH(CH₂CH₃)CH₂OH 1448. N(CH₂OCH₃)CH(CH₂CH₃)—CH₂OCH₃ 1449. N(CH₂CH₃)CH(CH₂CH₃)CH₂O— CH₂CH₃ 1450. N(CH₂OCH₃)CH(CH₂CH₃)CH₂O— (CH₂)₂CH₃ 1451. N(CH₂OCH₃)CH(CH₂CH₃)CH₂O— CH(CH₃)₂ 1452. N(CH₂OCH₃)CH(CH₂CH₃)CH₂O— CH₂OCH₃ 1453. N(CH₂OCH₃)CH(CH₂CH)CH₂OH 1454. N(CH₂OCH₃)CH(CH₂CH)—CH₂OCH₃ 1455. N(CH₂OCH₃)CH(CH₂CH)CH₂O— CH₂CH₃ 1456. N(CH₂OCH₃)CH(CH₂CH)CH₂O— (CH₂)₂CH₃ 1457. N(CH₂OCH₃)CH(CH₂CH)CH₂O— CH(CH₃)₂ 1458. N(CH₂OCH₃)CH(CH₂CH)CH₂O— CH₂OCH₃ 1459. N(CH₂OCH₃)CH(CH₂OCH₃)—CH₂OH 1460. N(CH₂OCH₃)CH(CH₂OCH₃)CH₂O— CH₃ 1461. N(CH₂OCH₃)CH(CH₂OCH₃)CH₂O— CH₂CH₃ 1462. N(CH₂OCH₃)CH(CH₂OCH₃)CH₂O— (CH₂)₂CH₃ 1463. N(CH₂OCH₃)CH(CH₂OCH₃)CH₂O— CH(CH₃)₂ 1464. N(CH₂OCH₃)CH(CH₂OCH₃)CH₂O— CH₂OCH₃ 1465. N(CH₂OCH₃)CH₂CH(CH₃)OH 1466. N(CH₂OCH₃)CH₂CH(CH₃)OCH₃ 1467. N(CH₂OCH₃)CH₂CH(CH₃)O—CH₂CH₃ 1468. N(CH₂OCH₃)CH₂CH(CH₃)O— (CH₂)₂CH₃ 1469. N(CH₂OCH₃)CH₂CH(CH₃)O— CH(CH₃)₂ 1470. N(CH₂OCH₃)CH₂CH(CH₃)O— CH₂OCH₃ 1471. N(CH₂OCH₃)CH₂CH(CH₂CH₃)OH 1472. N(CH₂OCH₃)CH₂CH(CH₂CH₃)—OCH₃ 1473. N(CH₂OCH₃)CH₂CH(CH₂CH₃)O— CH₂CH₃ 1474. N(CH₂OCH₃)CH₂CH(CH₂CH₃)O— (CH₂)₂CH₃ 1475. N(CH₂OCH₃)CH₂CH(CH₂CH₃)O— CH(CH₃)₂ 1476. N(CH₂OCH₃)CH₂CH(CH₂CH₃)O— CH₂OCH₃ 1477. N(CH₂OCH₃)CH₂CH(CH₂CH)OH 1478. N(CH₂OCH₃)CH₂CH(CH₂CH)—OCH₃ 1479. N(CH₂OCH₃)CH₂CH(CH₂CH)O— CH₂CH₃ 1480. N(CH₂OCH₃)CH₂CH(CH₂CH)— (CH₂CH)O—(CH₂)₂CH₃ 1481. N(CH₂OCH₃)CH₂CH(CH₂CH)— OCH(CH₃)₂ 1482. N(CH₂OCH₃)CH₂CH(CH₂CH)O— CH₂OCH₃ 1483. N(CH₂OCH₃)CH₂CH(CH₂OCH₃)—OH 1484. N(CH₂OCH₃)CH₂CH(CH₂OCH₃)O— CH₃ 1485. N(CH₂OCH₃)CH₂CH(CH₂OCH₃)O— CH₂CH₃ 1486. N(CH₂OCH₃)CH₂CH(CH₂OCH₃)O— (CH₂)₂CH₃ 1487. N(CH₂OCH₃)CH₂CH(CH₂OCH₃)O— CH(CH₃)₂ 1488. N(CH₂OCH₃)CH₂CH(CH₂OCH₃)O— CH₂OCH₃ 1489. N(CH₂OCH₃)CH(CH₃)CH₂CH₂OH 1490. N(CH₂OCH₃)CH(CH₃)—CH₂CH₂OCH₃ 1491. N(CH₂OCH₃)CH(CH₃)CH₂CH₂O— CH₂CH₃ 1492. N(CH₂OCH₃)CH(CH₃)CH₂CH₂O— (CH₂)₂CH₃ 1493. N(CH₂OCH₃)CH(CH₃)CH₂CH₂O— CH(CH₃)₂ 1494. N(CH₂OCH₃)CH(CH₃)CH₂CH₂O— CH₂OCH₃ 1495. N(CH₂OCH₃)CH(CH₂CH₃)— CH₂CH₂OH 1496. N(CH₂OCH₃)CH(CH₂CH₃)— CH₂CH₂OCH₃ 1497. N(CH₂OCH₃)CH(CH₂CH₃)— CH₂CH₂OCH₂CH₃ 1498. N(CH₂OCH₃)CH(CH₂CH₃)— CH₂CH₂O(CH₂)₂CH₃ 1499. N(CH₂OCH₃)CH(CH₂CH₃)— CH₂CH₂OCH(CH₃)₂ 1500. N(CH₂OCH₃)CH(CH₂CH₃)— CH₂CH₂OCH₂OCH₃ 1501. N(CH₂OCH₃)C[(CH₃)₂]CH₂CH₂OH 1502. N(CH₂OCH₃)C[(CH₃)₂— CH₂CH₂OCH₃ 1503. N(CH₂OCH₃)C[(CH₃)₂]CH₂CH₂O— CH₂CH₃ 1504. N(CH₂OCH₃)C[(CH₃)₂]CH₂CH₂O— (CH₂)₂CH₃ 1505. N(CH₂OCH₃)C[(CH₃)₂]CH₂CH₂O— CH(CH₃)₂ 1506. N(CH₂OCH₃)C[(CH₃)₂]CH₂CH₂O— CH₂OCH₃ 1507. N(CH₂OCH₃)CH(CH₂CH)— CH₂CH₂OH 1508. N(CH₂OCH₃)CH(CH₂CH)— CH₂CH₂OCH₃ 1509. N(CH₂OCH₃)CH(CH₂CH)— CH₂CH₂OCH₂CH₃ 1510. N(CH₂OCH₃)CH(CH₂CH)— CH₂CH₂O(CH₂)₂CH₃ 1511. N(CH₂OCH₃)CH(CH₂CH)— CH₂CH₂OCH(CH₃)₂ 1512. N(CH₂OCH₃)CH(CH₂CH)— CH₂CH₂OCH₂OCH₃ 1513. N(CH₂OCH₃)CH(CH₂OCH₃)— CH₂CH₂OH 1514. N(CH₂OCH₃)CH(CH₂OCH₃)— CH₂CH₂OCH₃ 1515. N(CH₂OCH₃)CH(CH₂OCH₃)— CH₂CH₂OCH₂CH₃ 1516. N(CH₂OCH₃)CH(CH₂OCH₃)— CH₂CH₂O(CH₂)₂CH₃ 1517. N(CH₂OCH₃)CH(CH₂OCH₃)— CH₂CH₂OCH(CH₃)₂ 1518. N(CH₂OCH₃)CH(CH₂OCH₃)— CH₂CH₂OCH₂OCH₃ 1519. NHCH₂CH(OCH₃)₂ 1520. NHCH₂CH(OCH₂CH₃)₂ 1521. NHCH(CH₃)CH(OCH₃)₂ 1522. NHCH(CH₃)CH(OCH₂CH₃)₂ 1523. NHCH(CH₂CH₃)CH(OCH₃)₂ 1524. NHCH(CH₂CH₃)CH(OCH₂CH₃)₂ 1525. NHCH(CH₂CH₂CH₃)CH(OCH₃)₂ 1526. NHCH(CH₂CH₂CH₃)-CH(OCH₂CH₃)₂ 1527. NHCH₂CH₂CH(OCH₃)₂ 1528. NHCH₂CH₂CH(OCH₂CH₃)₂ 1529. NHCH(CH₃)CH₂CH(OCH₃)₂ 1530. NHCH(CH₃)CH₂CH(OCH₂CH₃)₂ 1531. NHCH(CH₂CH₃)CH₂CH(OCH₃)₂ 1532. NHCH(CH₂CH₃)-CH₂CH(OCH₂CH₃)₂ 1533. NHCH(CH₂CH₂CH₃)—CH₂CH(OCH₃)₂ 1534. NHCH(CH₂CH₂CH₃)— CH₂CH(OCH₂CH₃)₂ 1535. NHCH₂C(CH₃)(OCH₃)₂ 1536. NHCH₂C(CH₃)(OCH₂CH₃)₂ 1537. NHCH(CH₃)C (CH₃)(OCH₃)₂ 1538. NHCH(CH₃)C(CH₃)(OCH₂CH₃)₂ 1539. NHCH(CH₂CH₃)C(CH₃)(OCH₃)₂ 1540. NHCH(CH₂CH₃)-C(CH₃)(OCH₂CH₃)₂ 1541. NHCH(CH₂CH₂CH₃)-C(CH₃)(OCH₃)₂ 1542. NHCH(CH₂CH₂CH₃)— C(CH₃)(OCH₂CH₃)₂ 1543. NHCH₂CH₂C(CH₃)(OCH₃)₂ 1544. NHCH₂CH₂C(CH₃)(OCH₂CH₃)₂ 1545. NNCH(CH₃)CH₂C(CH₃)(OCH₃)₂ 1546. NHCH(CH₃)—CH₂C(CH₃)(OCH₂CH₃)₂ 1547. NHCH(CH₂CH₃)—CH₂C(CH₃)(OCH₃)₂ 1548. NHCH(CH₂CH₃)— CH₂C(CH₃)(OCH₂CH₃)₂ 1549. NHCH(CH₂CH₂CH₃)— CH₂C(CH₃)(OCH₃)₂ 1550. NHCH(CH₂CH₂CH₃) — CH₂C(CH₃)(OCH₂CH₃)₂ 1551. NHCH₂CH(SCH₃)₂ 1552. NHCH₂CH(SCH₂CH₃)₂ 1553. NHCH(CH₃)CH(SCH₃)₂ 1554. NHCH(CH₃)CH(SCH₂CH₃)₂ 1555. NHCH(CH₂CH₃)CH(SCH₃)₂ 1556. NHCH(CH₂CH₃)CH(SCH₂CH₃)₂ 1557. NHCH(CH₂CH₂CH₃)CH(SCH₃)₂ 1558. NHCH(CH₂CH₂CH₃)—CH(SCH₂CH₃)₂ 1559. NHCH₂CH₂CH(SCH₃)₂ 1560. NHCH₂CH₂CH(SCH₂CH₃)₂ 1561. NHCH(CH₃)CH₂CH(SCH₃)₂ 1562. NHCH(CH₃)CH₂CH(SCH₂CH₃)₂ 1563. NHCH(CH₂CH₃)CH₂CH(SCH₃)₂ 1564. NHCH(CH₂CH₃)—CH₂CH(SCH₂CH₃)₂ 1565. NHCH(CH₂CH₂CH₃)—CH₂CH(SCH₃)₂ 1566. NHCH(CH₂CH₂CH₃) — CH₂CH(SCH₂CH₃)₂ 1567. NHCH₂CH₂SCH₃ 1568. NHCH₂CH₂SCH₂CH₃ 1569. NHCH₂CH₂S(CH₂)₂CH₃ 1570. NHCH₂CH₂SCH(CH₃)₂ 1571. NHCH₂CH₂CH₂SCH₃ 1572. NHCH₂CH₂CH₂SCH₂CH₃ 1573. NKCH₂CH₂CH₂S(CH₂)₂CH₃ 1574. NHCH₂CH₂CH₂SCH(CH₃)₂ 1575. NHCH(CH₃)CH₂SCH₃ 1576. NHCH(CH₃)CH₂SCH₂CH₃ 1577. NHCH(CH₃)CH₂S(CH₂)₂CH₃ 1578. NHCH(CH₃)CH₂SCH(CH₃)₂ 1579. NHCH(CH₃)CH₂CH₂SCH₃ 1580. NHCH(CH₃)CH₂CH₂SCH₂CH₃ 1581. NHCH(CH₃)CH₂CH₂S(CH₂)₂CH₃ 1582. NHCH(CH₃)CH₂CH₂SCH(CH₃)₂ 1583. NHC[(CH₃)₂]CH₂SCH₃ 1584. NHC[(CH₃)₂]CH₂SCH₂CH₃ 1585. NHC[(CH₃)₂]CH₂S(CH₂)₂CH₃ 1586. NHC[(CH₃)₂]CH₂SCH(CH₃)₂ 1587. NHC[(CH₃)₂]CH₂CH₂SCH₃ 1588. NHC[(CH₃)₂]CH₂CH₂SCH₂CH₃ 1589. NHC[(CH₃)₂]CH₂CH₂S(CH₂)₂CH₃ 1590. NHC[(CH₃)₂]CH₂CH₂SCH(CH₃)₂ 1591. NHCH₂CH₂S(O)CH₃ 1592. NHCH₂CH₂S(O)CH₂CH₃ 1593. NHCH₂CH₂S(O)(CH₂)₂CH₃ 1594. NHCH₂CH₂S(O)CH(CH₃)₂ 1595. NHCH₂CH₂CH₂S(O)CH₃ 1596. NHCH₂CH₂CH₂S(O)CH₂CH₃ 1597. NHCH₂CH₂CH₂S(O)(CH₂)₂CH₃ 1598. NHCH₂CH₂CH₂S(O)CH(CH₃)₂ 1599. NHCH(CH₃)CH₂S(O)CH₃ 1600. NHCH(CH₃)CH₂S(O)CH₂CH₃ 1601. NHCH(CH₃)CH₂S(O)(CH₂)₂CH₃ 1602. NHCH(CH₃)CH₂S(O)CH(CH₃)₂ 1603. NHCH(CH₃)CH₂CH₂S(O)CH₃ 1604. NHCH(CH₃)CH₂CH₂S(O)CH₂CH₃ 1605. NHCH(CH₃)CH₂CH₂S(O)—(CH₂)₂CH₃ 1606. NHCH(CH₃)CH₂CH₂S(O)—CH(CH₃)₂ 1607. NHC[(CH₃)₂]CH₂S(O)CH₃ 1608. NHC[(CH₃)23CH₂S(O)CH₂CH₃ 1609. NHC[(CH₃)₂]CH₂S(O)(CH₂)₂CH₃ 1610. NHC[(CH₃)₂]CH₂S(O)CH(CH₃)₂ 1611. NHC[(CH₃)₂]CH₂CH₂S(O)CH₃ 1612. NHC[(CH₃)₂]CH₂CH₂S(O)CH₂CH₃ 1613. NHC[(CH₃)₂]CH₂CH₂S(O)—(CH₂)₂CH₃ 1614. NHC[(CH₃)₂]CH₂CH₂S(O)—CH(CH₃)₂ 1615. NHCH₂CH₂S(O)₂CH₃ 1616. NHCH₂CH₂S(O)₂CH₂CH₃ 1617. NHCH₂CH₂S(O)2(CH₂)₂CH₃ 1618. NHCH₂CH₂S(O)₂CH(CH₃)₂ 1619. NHCH₂CH₂CH₂S(O)₂CH₃ 1620. NHCH₂CH₂CH₂S(O)₂CH₂CH₃ 1621. NHCH₂CH₂CH₂S(O)₂(CH₂)₂CH₃ 1622. NHCH₂CH₂CH₂S(O)₂CH(CH₃)₂ 1623. NHCH(CH₃)CH₂S(O)₂CH₃ 1624. NHCH(CH₃)CH₂S(O)₂CH₂CH₃ 1625. NHCH(CH₃)CH₂S(O)₂(CH₂)₂CH₃ 1626. NHCH(CH₃)CH₂S(O)₂CH(CH₃)₂ 1627. NHCH(CH₃)CH₂CH₂S(O)₂CH₃ 1628. NHCH(CH₃)CH₂CH₂S(O)₂CH₂CH₃ 1629. NHCH(CH₃)CH₂CH₂S(O)₂—(CH₂)₂CH₃ 1630. NHCH(CH₃)CH₂CH₂S(O)_CH(CH₃)₂ 1631. NHC[(CH₃)₂]CH₂S(O)₂CH₃ 1632. NHC[(CH₃)₂)CH₂S(O)₂CH₂CH₃ 1633. NHC[(CH₃)₂]CH₂S(O)₂(CH₂)₂CH₃ 1634. NHC[(CH₃)2JCH₂S(O)₂CH(CH₃)₂ 1635. NHC[(CH₃)₂]CH₂CH₂S(O)₂CH₃ 1636. NHC[(CH₃)₂]CH₂CH₂S(O)₂—CH₂CH₃ 1637. NHC[(CH₃)₂]CH₂CH₂S(O)₂— (CH₂)₂CH₃ 1638. NHC[(CH₃)₂]CH₂CH₂S(O)₂—CH(CH₃)₂ 1639. NHCH₂CH₂Si(OCH₃)₃ 1640. NHCH₂CH₂Si(OCH₂CH₃)₃ 1641. NHCH(CH₃)CH₂Si(OCH₃)₃ 1642. NHCH(CH₃)CH₂Si(OCH₂CH₃)₃ 1643. NHCH₂CH₂CH₂Si(OCH₃)₃ 1644. NHCH₂CH₂CH₂Si(OCH₂CH₃)₃ 1645. NHCH(CH₃)CH₂CH₂Si(OCH₃)₃ 1646. NHCH(CH₃)CH₂CH2-Si(OCH₂CH₃)₃ 1647.

1648.

1649.

1650.

1651.

1652.

1653.

1654.

1655.

1656.

1657.

1658.

1659.

1660.

1661.

1662.

1663.

1664.

1665.

1666.

1667.

1668.

1669.

1670.

1671.

1672.

1673.

1674.

1675.

1676.

1677.

1678.

1679.

1680.

1681.

1682. HNCH₂N═C(NH₂)NH₂ 1683. HNCH₂CH₂N═C(NH₂)NH₂ 1684. HNCH₂CH₂CH₂N═C(NH₂)NH₂ 1685. HNCH(CH₃)N═C(NH₂)NH₂ 1686. HNCH(CH₃)CH₂N═C(NH₂)NH₂ 1687. HNCH(CH₃)CH₂CH₂N═C(NH₂)NH₂ 1688. HNCH₂CH(CH₃)N═C(NH₂)NH₂ 1689. HNCH₂CH₂CH(CH₃)N═C(NH₂)NH₂ 1690. HNCH(CH₃)CH(CH₃)—N═C(NH₂)NH₂ 1691. HNCH(CH₃)CH₂CH(CH₃)— N═C(NH₂)NH₂ 1692. NHCH₂-(2-pyridyl) 1693. NHCH₂CH₂-(2-pyridyl) 1694. NHCH₂CH₂CH₂-(2-pyridyl) 1695. NHCH(CH₃)—(2-pyridyl) 1696. NHCH(CH₃)CH₂-(2-pyridyl) 1697. NHCH(CH₃)CH₂CH₂-(2-pyridyl) 1698. NHCH(CH₂CH₃)—(2-pyridyl) 1699. NHCH(CH₂CH₃)CH₂-(2-pyridyl) 1700. NHCH(CH₂CH₃)CH₂CH₂- (2-pyridyl) 1701. NHCH₂CH₂O-(2-pyridyl) 1702. NHCH₂CH₂CH₂O-(2-pyridyl) 1703. NHCH(CH₃)O-(2-pyridyl) 1704. NHCH(CH₃)CH₂O-(2-pyridyl) 1705. NHCH(CH₃)CH₂CH₂O-(2-pyridyl) 1706. NHCH(CH₂CH₃)O-(2-pyridyl) 1707. NHCH(CH₂CH₃)CH₂O-(2-pyridyl) 1708. NHCH(CH₂CH₃)CH₂CH₂O— (2-pyridyl) 1709. NHCH₂-(3-pyridyl) 1710. NHCH₂CH₂-(3-pyridyl) 1711. NHCH₂CH₂CH₂-(3-pyridyl) 1712. NHCH(CH₃)-(3-pyridyl) 1713. NHCH(CH₃)CH₂-(3-pyridyl) 1714. NHCH(CH₃)CH₂CH₂-(3-pyridyl) 1715. NHCH(CH₂CH₃)-(3-pyridyl) 1716. NHCH(CH₂CH₃)CH₂-(3-pyridyl) 1717. NHCH(CH₂CH₃)CH₂CH- (3-pyridyl) 1718. NHCH₂CH₂O-(3-pyridyl) 1719. N HCH₂CH₂CH₂O-(3-pyridyi) 1720. NHCH(CH₃)O-(3-pyridyl) 1721. NHCH(CH₃)CH₂O-(3-pyridyl) 1722. NHCH(CH₃)CH₂CH₂O-(3-pyridyl) 1723. NHCH(CH₂CH₃)O-(3-pyridyl) 1724. NHCH(CH₂CH₃)CH₂O-(3-pyridyl) 1725. NHCH(CH₂CH₃)CH₂CH₂O- (3-pyridyl) 1726. NHCH₂-(4-pyridyl) 1727. NHCH₂CH₂-(4-pyridyl) 1728. NHCH₂CH₂CH₂-(4-pyridyl) 1729. NHCH(CH₃)—(4-pyridyl) 1730. NHCH(CH₃)CH₂-(4-pyridyl) 1731. N HCH(CH₃)CH₂CH₂-(4-pyridyl) 1732. NHCH(CH₂CH₃)-(4-pyridyl) 1733. NHCH(CH₂CH₃)CH₂-(4-pyridyl) 1734. NHCH(CH₂CH₃)CH₂CH₂- (4-pyridyl) 1735. NHCH₂CH₂O-(4-pyridyl) 1736. NHCH₂CH₂CH₂O-(4-pyridyl) 1737. NHCH(CH₃)O-(4-pyridyl) 1738. NHCH(CH₃)CH₂O-(4-pyridyl) 1739. NHCH(CH₃)CH₂CH₂O-(4-pyridyl) 1740. NHCH(CH₂CH₃)O-(4-pyridyl) 1741. NHCH(CH₂CH₃)CH₂O-(4-pyridyl) 1742. NHCH(CH₂CH₃)CH₂CH₂O- (4-pyridyl) 1743. NHCH₂-(2-pyrimidyl) 1744. NHCH₂CH₂-(2-pyrimidyl) 1745. NHCH₂CH₂CH₂-(2-pyrimidyl) 1746. NHCH(CH₃)-(2-pyrimidyl) 1747. NHCH(CH₃)CH₂-(2-pyrimidyl) 1748. NHCH(CH₃)CH₂CH₂-(2-pyrimidyl) 1749. NHCH(CH₂CH₃)-(2-pyrimidyl) 1750. NHCH(CH₂CH₃)CH₂-(2-pyrimidyl) 1751. NHCH(CH₂CH₃)CH₂CH₂- (2-pyrimidyl) 1752. NHCH₂CH₂O-(2-pyrimidyl) 1753. NHCH₂CH₂CH₂O-(2-pyrimidyl) 1754. NHCH(CH₃)O-(2-pyrimidyl) 1755. NHCH(CH₃)CH₂O-(2-pyrimidyl) 1756. NHCH(CH₃)CH₂CH₂O-(2-pyrimidyl) 1757. NHCH(CH₂CH₃)O-(2-pyrimidyl) 1758. NHCH(CH₂CH₃)CH₂O-(2-pyrimidyl) 1759. NHCH(CH₂CH₃)CH₂CH₂O- (2-pyrimidyl) 1760. NHCH₂-(4-pyrimidyl) 1761. NHCH₂CH₂-(4-pyrimidyl) 1762. NHCH₂CH₂CH₂-(4-pyrimidyl) 1763. NHCH(CH₃)-(4-pyrimidyl) 1764. NHCH(CH₃)CH₂-(4-pyrimidyl) 1765. NHCH(CH₃)CH₂CH₂-(4-pyrimidyl) 1766. NHCH(CH₂CH₃)-(4-pyrimidyl) 1767. NHCH(CH₂CH₃)CH₂-(4-pyrimidyl) 1768. NHCH(CH₂CH₃)CH₂CH₂- (4-pyrimidyl) 1769. NHCH₂CH₂O-(4-pyrimidyl) 1770. NHCH₂CH₂CH₂O-(4-pyrimidyl) 1771. NHCH(CH₃)O-(4-pyrimidyl) 1772. NHCH(CH₃)CH₂O-(4-pyrimidyl) 1773. NHCH(CH₃)CH₂CH₂O-(4-pyrimidyl) 1774. NHCH(CH₂CH₃)O-(4-pyrimidyl) 1775. NHCH(CH₂CH₃)CH₂O-(4-pyrimidyl) 1776. NHCH(CH₂CH₃)CH₂CH₂O- (4-pyrimidyl) 1777. NHCH₂-(5-pyrimidyl) 1778. NHCH₂CH₂-(5-pyrimidyl) 1779. NHCH₂CH₂CH₂-(5-pyrimidyl) 1780. NHCH(CH₃)-(5-pyrimidyl) 1781. NHCH(CH₃)CH₂-(5-pyrimidyl) 1782. NHCH(CH₃)CH₂CH₂-(5-pyrimidyl) 1783. NHCH(CH₂CH₃)—(5-pyrimidyl) 1784. NHCH(CH₂CH₃)CH₂-(5-pyrimidyl) 1785. NHCH(CH₂CH₃)CH₂CH₂- (5-pyrimidyl) 1786. NHCH₂CH₂O-(5-pyrimidyl) 1787. NHCH₂CH₂CH₂O-(5-pyrimidyl) 1788. NHCH(CH₃)O-(5-pyrimidyl) 1789. NHCH(CH₃)CH₂O-(5-pyrimidyl) 1790. NHCH(CH₃)CH₂CH₂O-(5-pyrimidyl) 1791. NHCH(CH₂CH₃)O-(5-pyrimidyl) 1792. NHCH(CH₂CH₃)CH₂O-(5-pyrimidyl) 1793. NHCH(CH₂CH₃)CH₂CH₂O- (5-pyrimidyl) 1794. NHCH₂-(1,3,5-triazinyl) 1795. NHCH₂CH₂-(1,3,5-triazinyl) 1796. NHCH₂CH₂CH₂-(1,3,5-triazinyl) 1797. NHCH(CH₃)—(1,3,5-triazinyl) 1798. NHCH(CH₃)CH₂-(1,3,5-triazinyl) 1799. NHCH(CH₃)CH₂CH₂- (1,3,5-triazinyl) 1800. NHCH(CH₂CH₃)-(1,3,5-triazinyl) 1801. NHCH(CH₂CH₃)CH₂- (1,3,5-triazinyl) 1802. NHCH(CH₂CH₃)CH₂CH₂- (1,3,5-triazinyl) 1803. NHCH₂CH₂O-(1,3,5-triazinyl) 1804. NHCH₂CH₂CH₂O-(1,3,5-triazinyl) 1805. NHCH(CH₃)O-(1,3,5-triazinyl) 1806. NHCH(CH₃)CH₂O-(1,3,5-triazinyl) 1807. NHCH(CH₃)CH₂CH₂O- (1,3,5-triazinyl) 1808. NHCH(CH₂CH₃)O-(1,3,5-triazinyl) 1809. NHCH(CH₂CH₃)CH₂O- (1,3,5-triazinyl) 1810. NHCH(CH₂CH₃)CH₂CH₂O- (1,3,5-triazinyl) 1811. NHCH₂-(2-thiazolyl) 1812. NHCH₂CH₂-(2-thiazolyl) 1813. NHCH₂CH₂CH₂-(2-thiazolyl) 1814. NHCH(CH₃)-(2-thiazolyl) 1815. NHCH(CH₃)CH₂-(2-thiazolyl) 1816. NHCH(CH₃)CH₂CH₂-(2-thiazolyl) 1817. NHCH(CH₂CHs)—(2-thiazolyl) 1818. NHCH(CH₂CH₃)CH₂-(2-thiazolyl) 1819. NHCH(CH₂CH₃)CH₂CH₂- (2-thiazolyl) 1820. NHCH₂CH₂O-(2-thiazolyl) 1821. NHCH₂CH₂CH₂O-(2-thiazolyl) 1822. NHCH(CH₃)O-(2-thiazolyl) 1823. NHCH(CH₃)CH₂O-(2-thiazolyl) 1824. NHCH(CH₃)CH₂CH₂O-(2-thiazolyl) 1825. NHCH(CH₂CH₃)O-(2-thiazolyl) 1826. NHCH(CH₂CH₃)CH₂O-(2-thiazolyl) 1827. NHCH(CH₂CH₃)CH₂CH₂O- (2-thiazolyl) 1828. NHCH₂-(4-thiazolyl) 1829. NHCH₂CH₂-(4-thiazolyl) 1830. NHCH₂CHaCH₂-(4-thiazolyl) 1831. NHCH(CH₃)-(4-thiazolyl) 1832. NHCH(CH₃)CH₂-(4-thiazolyl) 1833. NHCH(CH₃)CH₂CH₂-(4-thiazolyl) 1834. NHCH(CH₂CH₃)—(4-thiazolyl) 1835. NHCH(CH₂CH₃)CH₂-(4-thiazolyl) 1836. NHCH(C H₂CH₃)CH₂CH₂- (4-thiazolyl) 1837. NHCH₂CH₂O-(4-thiazolyl) 1838. NHCH₂CH₂CH₂O-(4-thiazolyl) 1839. NHCH(CH₃)O-(4-thiazolyl) 1840. NHCH(CH₃)CH₂O-(4-thiazolyl) 1841. NHCH(CH₃)CH₂CH₂O-(4-thiazolyl) 1842. NHCH(CH₂CH₃)O-(4-thiazolyl) 1843. NHCH(CH₂CH₃)CH₂O-(4-thiazolyl) 1844. NHCH(CH₂CH₃)CH₂CH₂O- (4-thiazolyl) 1845. NHCH₂-(5-thiazolyl) 1846. NHCH₂CH₂-(5-thiazolyl) 1847. NHCH₂CH₂CH₂-(5-thiazolyl) 1848. NHCH(CH₃)-(5-thiazolyl) 1849. NHCH(CH₃)CH₂-(5-thiazolyl) 1850. NHCH(CH₃)CH₂CH₂-(5-thiazolyl) 1851. NHCH(CH₂CH₃)-(5-thiazolyl) 1852. NHCH(CH₂CH₃)CH₂-(5-thiazolyl) 1853. NHCH(CH₂CH₃)CH₂CH₂- (5-thiazolyl) 1854. NHCH₂CH₂O-(5-thiazolyl) 1855. NHCH₂CH₂CH₂O-(5-thiazolyl) 1856. NHCH(CH₃)O-(5-thiazolyl) 1857. NHCH(CH₃)CH₂O-(5-thiazolyl) 1858. NHCH(CH₃)CH₂CH₂O-(5-thiazolyl) 1859. NHCH(CH₂CH₃)O-(5-thiazolyl) 1860. NHCH(CH₂CH₃)CH₂O-(5-thiazolyl) 1861. NHCH(CH₂CH₃)CH₂CH₂O- (5-thiazolyl) 1862. NHCH₂-(2-furyl) 1863. NHCH₂CH₂-(2-furyl) 1864. NHCH₂CH₂CH₂-(2-furyl) 1865. NHCH(CH₃)—(2-furyl) 1866. NHCH(CH₃)CH₂-(2-furyl) 1867. NHCH(CH₃)CH₂CH₂-(2-furyl) 1868. NHCH(CH₂CH₃)-(2-furyl) 1869. NHCH(CH₂CH₃)CH₂-(2-furyl) 1870. NHCH(CH₂CH₃)CH₂CH₂- (2-furyl) 1871. NHCH₂CH₂O-(2-furyl) 1872. NHCH₂CH₂CH₂O-(2-furyl) 1873. NHCH(CH₃)O-(2-furyl) 1874. NHCH(CH₃)CH₂O-(2-furyl) 1875. NHCH(CH₃)CH₂CH₂O-(2-furyl) 1876. NHCH(CH₂CH₃)O-(2-furyl) 1877. NHCH(CH₂CH₃)CH₂O-(2-furyl) 1878. NHCH(CH₂CH₃)CH₂CH₂O- (2-furyl) 1879. NHCH₂-(3-furyl) 1880. NHCH₂CH₂-(3-furyl) 1881. NHCH₂CH₂CH₂-(3-furyl) 1882. NHCH(CH₃)—(3-furyl) 1883. NHCH(CH₃)CH₂-(3-furyl) 1884. NHCH(CH₃)CH₂CH₂-(3-furyl) 1885. NHCH(CH₂CH₃)—(3-furyl) 1886. NHCH(CH₂CH₃)CH₂-(3-furyl) 1887. NHCH(CH₂CH₃)CH₂CH₂- (3-furyl) 1888. NHCH₂CH₂O-(3-furyl) 1889. NHCH₂CH₂CH₂O-(3-furyl) 1890. NHCH(CH₃)O-(3-furyl) 1891. NHCH(CH₃)CH₂O-(3-furyl) 1892. NHCH(CH₃)CH₂CH₂O-(3-furyl) 1893. NHCH(CH₂CHs)O-(3-furyl) 1894. NHCH(CH₂CH₃)CH₂O-(3-furyl) 1895. NHCH(CH₂CH₃)CH₂CH₂O- (3-furyl) 1896. NHCH₂-(2-thienyl) 1897. NHCH₂CH₂-(2-thienyl) 1898. NHCH₂CH₂CH₂-(2-thienyl) 1899. NHCH(CH₃)—(2-thienyl) 1900. NHCH(CH₃)CH₂-(2-thienyl) 1901. NHCH(CH₃)CH₂CH₂-(2-thienyl) 1902. NHCH(CH₂CH₃)—(2-thienyl) 1903. NHCH(CH₂CH₃)CH₂-(2-thienyl) 1904. NHCH(CH₂CH₃)CH₂CH₂- (2-thienyl) 1905. NHCH₂CH₂O-(2-thienyl) 1906. NHCH₂CH₂CH₂O-(2-thienyl) 1907. NHCH(CH₃)O-(2-thienyl) 1908. NHCH(CH₃)CH₂O-(2-thienyl) 1909. NHCH(CH₃)CH₂CH₂O-(2-thienyl) 1910. NHCH(CH₂CH₃)O-(2-thienyl) 1911. NHCH(CH₂CH₃)CH₂O-(2-thienyl) 1912. NHCH(CH₂CH₃)CH₂CH₂O- (2-thienyl) 1913. NHCH₂-(3-thienyl) 1914. NHCH₂CH₂-(3-thienyl) 1915. NHCH₂CH₂CH₂-(3-thienyl) 1916. NHCH(CH₃)—(3-thienyl) 1917. NHCH(CH₃)CH₂-(3-thienyl) 1918. NHCH(CH₃)CH₂CH₂-(3-thienyl) 1919. NHCH(CH₂CH₃)—(3-thienyl) 1920. NHCH(CH₂CH₃)CH₂-(3-thienyl) 1921. NHCH(CH₂CH₃)CH₂CH₂- (3-thienyl) 1922. NHCH₂CH₂O-(3-thienyl) 1923. NHCH₂CH₂CH₂O-(3-thienyl) 1924. NHCH(CH₃)O-(3-thienyl) 1925. NHCH(CH₃)CH₂O-(3-thienyl) 1926. NHCH(CH₃)CH₂CH₂O-(3-thienyl) 1927. NHCH(CH₂CH₃)O-(3-thienyl) 1928. NHCH(CH₂CH₃)CH₂O-(3-thienyl) 1929. NHCH(CH₂CH₃)CH₂CH₂O- (3-thienyl) 1930. NHCH₂-(1-imidazolyl) 1931. NHCH₂CH₂-(1-imidazolyl) 1932. NHCH₂CH₂CH₂-(1-imidazolyl) 1933. NHCH(CH₃)—(1 -imidazolyl) 1934. NHCH(CH₃)CH₂-(1 -imidazolyl) 1935. NHCH(CH₃)CH₂CH₂-(1 -imidazolyl) 1936. NHCH₂CH(CH)₃CH₂-(1 -imidazolyl) 1937. NHCH₂CH₂CH(CH)₃-(1-imidazolyl) 1938. NHCH(CH₂CH₃)-(1-imidazolyl) 1939. NHCH(CH₂CH₃)CH₂-(1 -imidazolyl) 1940. NHCH(CH₂CH₃)CH₂CH₂- (1-imidazolyl) 1941. NHCH₂CH₂O-(1-imidazolyl) 1942. NHCH₂CH₂CH₂O-(1-imidazolyl) 1943. NHCH(CH₃)O-(1-imidazolyl) 1944. NHCH(CH₃)CH₂O-(1-imidazolyl) 1945. NHCH(CH₃)CH₂CH₂O- (1-imidazolyl) 1946. NHCH(CH₂CH₃)O-(1-imidazolyl) 1947. NHCH(CH₂CH₃)CH₂O- (1-imidazolyl) 1948. NHCH(CH₂CH₃)CH₂CH₂O- (1-imidazolyl) 1949. NHCH₂-(1-[1,2,4-triazolyl]) 1950. NHCH₂CH₂-(1-[1,2,4-triazolyl]) 1951. NHCH₂CH₂CH₂-(1-[1,2,4-triazolyl]) 1952. NHCH(CH₃)-(1-[1,2,4-triazolyl]) 1953. NHCH(CH₃)CH₂-(1-[1,2,4-triazolyl]) 1954. NHCH(CH₃)CH₂CH₂- (1-[1,2,4-triazolyl]) 1955. NHCH(CH₂CH₃)-(1-[1,2,4-triazolyl]) 1956. NHCH(CH₂CH₃)CH₂- (1-[1,2,4-triazolyl]) 1957. NHCH(CH₂CH₃)CH₂CH₂- (1-[1,2,4-triazolyl]) 1958. NHCH₂CH(CH)₃CH₂- (1-[1,2,4-triazolyl]) 1959. NHCH₂CH₂CH(CH)₃- (1-[1,2,4-triazolyl]) 1960. NHCH₂CH₂O-(1-[1,2,4-triazolyl]) 1961. NHCH₂CH₂CH₂O- (1-[1,2,4-triazolyl]) 1962. NHCH(CH₃)O-(1-[1,2,4-triazolyl]) 1963. NHCH(CH₃)CH₂O- (1-[1,2,4-triazolyl]) 1964. NHCH(CH₃)CH₂CH₂O- (1-[1,2,4-triazolyl]) 1965. NHCH(CH₂CH₃)O-(1-[1,2,4- triazolyl]) 1966. NHCH(CH₂CH₃)CH₂O- (1-[1,2,4-triazolyl]) 1967. NHCH(CH₂CH₃)CH₂CH₂O- (1-[1,2,4-triazolyl]) 1968. NHCH₂-(1-tetrazolyl) 1969. NHCH₂CH₂-(1-tetrazolyl) 1970. NHCH₂CH₂CH₂-(1-tetrazolyl) 1971. NHCH(CH₃)-(1-tetrazolyl) 1972. NHCH(CH₃)CH₂-(1-tetrazolyl) 1973. NHCH(CH₃)CH₂CH₂-(1-tetrazolyl) 1974. NHCH(CH₂CH₃)—(1-tetrazolyl) 1975. NHCH(CH₂CH₃)CH₂-(1-tetrazolyl) 1976. NHCH(CH₂CH₃)CH₂CH₂- (1-tetrazolyl) 1977. NHCH₂CH₂O-(1-tetrazolyl) 1978. NHCH₂CH₂CH₂O-(1-tetrazolyl) 1979. NHCH(CH₃)O-(1-tetrazolyl) 1980. NHCH(CH₃)CH₂O-(1-tetrazolyl) 1981. NHCH(CH₃)CH₂CH₂O- (1-tetrazolyl) 1982. NHCH(CH₂CH₃)O-(1-tetrazolyl) 1983. NHCH(CH₂CH₃)CH₂O- (1-tetrazolyl) 1984. NHCH(CH₂CH₃)CH₂CH₂O- (1-tetrazolyl) 1985. NHCHO 1986. NHCOCH₃ 1987. NHCOCH₂CH₃ 1988. NHCO(CH₂)₂CH₃ 1989. NHCO(CH₂)₃CH₃ 1990. NHCOCH(CH₃)₂ 1991. NHCOCH₂CH(CH₃)₂ 1992. NHCOC(CH₃)₃ 1993. NHCOCF₃ 1994. NHCOCF₂CF₃ 1995. NHCO(CF₂)₂CF₃ 1996. NHCOCH(CH)CH₃ 1997. NHCOCH(OCH₃)CH₃ 1998. NHCOCH₂CH(CH)CH₃ 1999. NHCOCH₂CH(OCH₃)CH₃ 2000. NHCOCH═CH₂ 2001. NHCOCH═CHCH₃ 2002. NHCOCH₂CH═CH₂ 2003. NHCOCH(CH₃)CH═CH₂ 2004. NHCOC≡OH 2005. NHCOC≡CCH₃ 2006. NHCOCH₂C≡OH 2007. NHCOCH(CH₃)C≡OH 2008. NHCOC≡CCl 2009. NHCOC≡CCH₂OH 2010. NHCOC≡CCH₂OCH₃ 2011. N(CH₃)CHO 2012. N(CH₃)COCH₃ 2013. N(CH₃)COCH₂CH₃ 2014. N(CH₃)CO(CH₂)₂CH₃ 2015. N(CH₃)CO(CH₂)₃CH₃ 2016. N(CH₃)COCH(CH₃)₂ 2017. N(CH₃)COCH₂CH(CH₃)₂ 2018. N(CH₃)COC(CH₃)₃ 2019. N(CH₃)COCF₃ 2020. N(CH₃)COCF₂CF₃ 2021. N(CH₂CH₃)CHO 2022. N(CH₂CH₃)COCH₃ 2023. N(CH₂CH₃)COCH₂CH₃ 2024. N(CH₂CH₃)CO(CH₂)₂CH₃ 2025. N(CH₂CH₃)CO(CH₂)₂CH₃ 2026. N(CH₂CH₃)COCH(CH₃)₂ 2027. N(CH₂CH₃)COCH₂CH(CH₃)₂ 2028. N(CH₂CH₃)COC(CH₃)₃ 2029. N(CH₂CH₃)COCF₃ 2030. N(CH₂CH₃)COCF₂CF₃ 2031. N(CH(CH₃)₂)CHO 2032. N(CH(CH₃)₂)COCH₃ 2033. N(CH(CH₃)₂)COCH₂CH₃ 2034. N(CH(CH₃)₂)CO(CH₂)₂CH₃ 2035. N(CH(CH₃)₂)CO(CH₂)₃CH₃ 2036. N(CH(CH₃)₂)COCH(CH₃)₂ 2037. N(CH(CH₃)₂)COCH₂CH(CH₃)₂ 2038. N(CH(CH₃)₂)COO(CH₃)₃ 2039. N(CH(CH₃)₂)COCF₃ 2040. N(CH(CH₃)₂COCF₂CF₃ 2041. N(CH(CH₂CH)CH₃)CHO 2042. N(CH(CH₂CH)CH₃)COCH₃ 2043. N(CH(CH₂CH)CH₃)COCH₂CH₃ 2044. N(CH(CH₂CH)CH₃)CO(CH₂)₂CH₃ 2045. N(CH(CH₂CH)CH₃)CO(CH₂)₃CH₃ 2046. N(CH(CH₂CH)CH₃)COCH(CH₃)₂ 2047. N(CH(CH₂CH)CH₃)COCH₂CH—(CH₃)₂ 2048. N(CH(CH₂CH)CH₃)COC(CH₃)₃ 2049. N(CH(CH₂CH)CH₃)COCF₃ 2050. N(CH(CH₂CH)CH₃)COCF₂CF₃ 2051. N(CH(CH₂OCH₃)CH₃)CHO 2052. N(CH(CH₂OCH₃)CH₃)COCH₃ 2053. N(CH(CH₂OCH₃)CH₃)COCH₂CH₃ 2054. N(CH(CH₂OCH₃)CH₃)CO—(CH₂)₂CH₃ 2055. N(CH(CH₂OCH₃)CH₃)CO—(CH₂)₃CH₃ 2056. N(CH(CH₂OCH₃)CH₃)CO—CH(CH₃)₂ 2057. N(CH(CH₂OCH₃)CH₃)CO— CH₂CH(CH₃)₂ 2058. N(CH(CH₂OCH₃)CH₃)COC(CH₃)₃ 2059. N(CH(CH₂OCH₃)CH₃)COCF₃ 2060. N(CH(CH₂OCH₃)CH₃)COCF₂CF₃ 2061. NHCOOCH₃ 2062. NHCOOCH₂CH₃ 2063. NHCOO(CH₂)₂CH₃ 2064. NHCOO(CH₂)₃CH₃ 2065. NHCOOCH(CH₃)₂ 2066. NHCOOCH₂CH(CH₃)₂ 2067. NHCOOC(CH₃)₃ 2068. NHCOOCH₂CF₃ 2069. NHCOOCH₂CHOCH₃ 2070. N(CH₃)COOCH₃ 2071. N(CH₃)COOCH₂CH₃ 2072. N(CH₃)COO(CH₂)₂CH₃ 2073. N(CH₃)COO(CH₂)₃CH₃ 2074. N(CH₃)COOCH(CH₃)₂ 2075. N(CH₃)COOCH₂CH(CH₃)₂ 2076. N(CH₃)COOC(CH₃)₃ 2077. N(CH₃)COOCH₂CF₃ 2078. N(CH₃)COOCH₂CHOCH₃ 2079. N(CH₂CH₃)COOCH₃ 2080. N(CH₂CH₃)COOCH₂CH₃ 2081. N(CH₂CH₃)COO(CH₂)₂CH₃ 2082. N(CH₂CH₃)COO(CH₂)₃CH₃ 2083. N(CH₂CH₃)COOCH(CH₃)₂ 2084. N(CH₂CH₃)COOCH₂CH(CH₃)₂ 2085. N(CH₂CH₃)COOC(CH₃)₃ 2086. N(CH₂CH₃)COOCH₂CF₃ 2087. N(CH₂CH₃)COOCH₂CHOCH₃ 2088. N(CH(CH₃)₂)COOCH₃ 2089. N(CH(CH₃)₂)COOCH₂CH₃ 2090. N(CH(CH₃)₂)COO(CH₂)₂CH₃ 2091. N(CH(CH₃)₂)COO(CH₂)₃CH₃ 2092. N(CH(CH₃)₂)COOCH(CH₃)₂ 2093. N(CH(CH₃)₂)COOCH₂CH(CH₃)₂ 2094. N(CH(CH₃)₂)COOC(CH₃)₃ 2095. N(CH(CH₃)₂)COOCH₂CF₃ 2096. N(CH(CH₃)₂)COOCH₂CHOCH₃ 2097. N(CH(CH₂CH)CH₃)COOCH₃ 2098. N(CH(CH₂CH)CH₃)COOCH₂CH₃ 2099. N(CH(CH₂CH)CH₃)COO—(CH₂)₂CH₃ 2100. N(CH(CH₂CH)CH₃)COO—(CH₂)₃CH₃ 2101. N(CH(CH₂CH)CH₃)COOCH(CH₃)₂ 2102. N(CH(CH₂CH)CH₃)COO— CH₂CH(CH₃)₂ 2103. N(CH(CH₂CH)CH₃)COOC(CH₃)₃ 2104. N(CH(CH₂CH)CH₃)COOCH₂CF₃ 2105. N(CH(CH₂CH)CH₃)COO— CH₂CHOCH₃ 2106. N(CH(CH₂OCH₃)CH₃)COOCH₃ 2107. N(CH(CH₂OCH₃)CH₃)COO—CH₂CH₃ 2108. N(CH(CH₂OCH₃)CH₃)COO— (CH₂)₂CH₃ 2109. N(CH(CH₂OCH₃)CH₃)COO— (CH₂)₃CH₃ 2110. N(CH(CH₂OCH₃)CH₃)COO— CH(CH₃)₂ 2111. N(CH(CH₂OCH₃)CH₃)COO— CH₂CH(CH₃)₂ 2112. N(CH(CH₂OCH₃)CH₃)COO—C(CH₃)₃ 2113. N(CH(CH₂OCH₃)CH₃)COO—CH₂CF₃ 2114. N(CH(CH₂OCH₃)CH₃)COO— CH₂CHOCH₃ 2115. NHCONHCH₃ 2116. NHCONHCH₂CH₃ 2117. NHCONH(CH₂)₂CH₃ 2118. NHCONH(CH₂)₃CH₃ 2119. NHCONHCH(CH₃)₂ 2120. NHCONHCH₂CH(CH₃)₂ 2121. NHCONHC(CH₃)₃ 2122. NHCONHCH₂CF₃ 2123. NHCONHCH₂CHOCH₃ 2124. N(CH₃)CONHCH₃ 2125. N(CH₃)CONHCH₂CH₃ 2126. N(CH₂CH₃)CONHCH₃ 2127. N(CH₂CH₃)CONHCH₂CH₃ 2128. N(CH(CH₃)₂)CONHCH₃ 2129. N(CH(CH₃)₂)CONHCH₂CH₃ 2130. N(CH(CH₂CH)CH₃)CONHCH₃ 2131. N(CH(CH₂CH)CH₃)CONHCH₂CH₃ 2132. N(CH(CH₂OCH₃)CH₃)CONHCH₃ 2133. N(CH(CH₂OCH₃)CH₃)CONH— CH₂CH₃ 2134. NHCON(CH₃)₂ 2135. NHCON(CH₂CH₃)₂ 2136. NHCON(CH₃)(CH₂)₂CH₃ 2137. NHCON(CH₃)(CH₂)₃CH₃ 2138. NHCON(CH₃)CH(CH₃)₂ 2139. NHCON(CH₃)CH₂CH(CH₃)₂ 2140. NHCON(CH₃)C(CH₃)₃ 2141. NHCON(CH₂CF₃)₂ 2142. NHCON(CH₂CHOCH₃)₂ 2143. NHSONHCH₃ 2144. NHSONHCH₂CH₃ 2145. NHSONH(CH₂)₂CH₃ 2146. NHSONH(CH₂)₃CH₃ 2147. NHSONHCH(CH₃)₂ 2148. NHSONHCH₂CH(CH₃)₂ 2149. NHSONHC(CH₃)₃ 2150. NHSONHCH₂CF₃ 2151. NHSONHCH₂CHOCH₃ 2152. NHSON(CH₃)₂ 2153. NHSON(CH₂CH₃)₂ 2154. NHSON(CH₃)(CH₂)₂CH₃ 2155. NHSON(CH₃)(CH₂)₃CH₃ 2156. NHSON(CH₃)CH(CH₃)₂ 2157. NHSON(CH₃)CH₂CH(CH₃)₂ 2158. NHSON(CH₃)C(CH₃)₃ 2159. NHSON(CH₂CF₃)₂ 2160. NHSON(CH₂CHOCH₃)₂ 2161. NHS(O)₂NHCH₃ 2162. NHS(O)₂NHCH₂CH₃ 2163. NHS(O)₂NH(CH₂)₂CH₃ 2164. NHS(O)₂NH(CH₂)₃CH₃ 2165. NHS(O)₂NHCH(CH₃)₂ 2166. NHS(O)₂NHCH₂CH(CH₃)₂ 2167. NHS(O)₂NHC(CH₃)₃ 2168. NHS(O)₂NHCH₂CF₃ 2169. NHS(O)₂NHCH₂CHOCH₃ 2170. NHS(O)₂N(CH₃)₂ 2171. NHS(O)₂N(CH₂CH₃)₂ 2172. NHS(O)₂N(CH₃)(CH₂)₂CH₃ 2173. NHS(O)₂N(CH₃)(CH₂)₃CH₃ 2174. NHS(O)₂N(CH₃)CH(CH₃)₂ 2175. NHS(O)₂N(CH₃)CH₂CH(CH₃)₂ 2176. NHS(O)₂N(CH₃)C(CH₃)₃ 2177. NHS(O)₂N(CH₂CF₃)₂ 2178. NHS(O)₂N(CH₂CHOCH₃)₂ 2179.

2180.

2181.

2182.

2183. N═CHNH₂ 2184. N═CHNH(CH₃) 2185. N═CHN(CH₃)₂ 2186. N═CHNH(CH₂CH₃) 2187. N═CHN(CH₂CH₃)₂ 2188. N═CHNCH₃(CH₂CH₃) 2189. N═C(CH₃)NH₂ 2190. N═C(CH₃)NH(CH₃) 2191. N═C(CH₃)N(CH₃)₂ 2192. N═C(CH₃)NH(CH₂CH₃) 2193. N═C(CH₃)N(CH₂CH₃)₂ 2194. N═C(CH₃)NCH₃(CH₂CH₃) 2195. N═C(CH₂CH₃)NH₂ 2196. N═C(CH₂CH₃)NH(CH₃) 2197. N═C(CH₂CH₃)N(CH₃)₂ 2198. N═C(CH₂CH₃)NH(CH₂CH₃) 2199. N═C(CH₂CH₃)N(CH₂CH₃)₂ 2200. N═C(CH₂CH₃)NCH₃(CH₂CH₃) 2201. N═C(NH₂)NH₂ 2202. N═C(NH₂)NH(CH₃) 2203. N═C(NH₂)N(CH₃)₂ 2204. N═C(NH₂)NH(CH₂CH₃) 2205. N═C(NH₂)N(CH₂CH₃)₂ 2206. N═C(NH₂)NCH₃(CH₂CH₃) 2207. N═C(NH(CH₃))NH(CH₃) 2208. N˜C(NH(CH₃))N(CH₃)₂ 2209. N═C(NH(CH₃))NH(CH₂CH₃) 2210. N˜C(NH(CH₃))N(CH₂CH₃)₂ 2211. N═C(NH(CH₃))NCH₃(CH₂CH₃) 2212. N═C(NH(CH₂CH₃))NH(CH₃) 2213. N═C(NH(CH₂CH₃))N(CH₃)₂ 2214. N═C(NH(CH₂CH₃))NH(CH₂CH₃) 2215. N═C(NH(CH₂CH₃))N(CH₂CH₃)₂ 2216. N═C(NH(CH₂CH₃))NCH₃(CH₂CH₃) 2217.

2218.

2219.

2220.

2221.

2222.

2223.

2224.

2225.

2226.

2227.

2228.

2229.

2230.

2231.

2232.

2233.

2234.

2235.

2236.

2237.

The invention especially relates to a the use of at least one compound of the formula I or a salt thereof for protecting a plant against attack or infestation by a phytopathogenic organism, especially a microorganism, especially a fungal organism (preferably selected from the group consisting of Ascomycetes, Basidiomycetes, Oomycetes and Fungi imperfecti), a bacterium, a virus or a nematode; said compound or salt being selected from the compounds given in Table A or especially in table 59, comprising administering said compound and/or salt to one or more selected from the group consisting of a plant, a part of a plant, seeds and the site of a plant.

Preferred are compounds of formula I, wherein n=0, R₁=halogen or haloalkoxy, each of R₂ to R₅ is hydrogen and R₆ is lower alkylamino wherein the lower alkyl moiety is substituted by one or more (preferably 1 to 3, especially 1 or 2) substitutents independently selected from the group consisting of unsubstituted amino, N-mono- or N,N-di-(lower alkyl)-amino, (lower alkoxy)-lower alkoxy, lower alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower alkylamino, hydroximino, alkoximino, guanidyl, lower alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower alkanoylamino, halo-lower alkanoylamino, lower alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino, lower alkoxy-lower alkylaminocarbonylamino, amidino, lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy, lower alkoxy-lower alkanoyloxy, hydroxy, lower alkoxy, lower alkenyloxy, lower alkinyloxy, lower haloalkoxy, piperazinyl, lower alkanoyl-piperazinyl (including formylpiperazinyl) and optionally substituted heteroaryloxy, or a salt thereof.

More preferred is a compound of formula I, wherein n=0, R₁=chlorine or haloalkoxy, each of R₂ to R₅ is hydrogen and R₆ is alkoxyalkylamino, or a salt thereof.

Especially preferred are compounds 4, 5, 12, 13, 14, 15, 32 and 40 of table 59.

The present invention also relates to the novel compounds of formula I mentioned hereinbefore and hereinafter, or salts thereof;

Especially preferred are the compounds with n=1 (N-oxides) of formula I, or the salts thereof.

Especially preferred is also a compound of formula I selected from the group of compounds provided in tables 1 to 58, or a salt thereof, or that total group of compounds, with the exception of

-   N-(3-trifluoromethyl-phenyl)-4-[2-(3-hydroxy-propyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(3-hydroxy-propyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-hydroxy-propyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-carboxy-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-carbamoyl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-ethoxycarbonyl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-trifluoromethyl-phenyl)-4-[2-(2-hydroxy-propyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-trifluoromethyl-phenyl)-4-[2-(2-carboxy-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-trifluoromethyl-phenyl)-4-[2-(2-carbamoyl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-trifluoromethyl-phenyl)-4-[2-(2-ethoxycarbonyl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-imidazol-1-yl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-acetamido-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-(2-hydrazino-4-pyridyl)-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-guanidyl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-{2-(methylamino-carbonylamino)-ethyl-amino}-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-amidino-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-{2-(N-hydroxy-carbamoyl)-ethyl-amino}-4-pyridyl]-2-pyrimidine-amine, -   N-(3-trifluormethyl-phenyl)-4-[2-{2-(N-hydroxy-carbamoyl)-ethyl-amino}-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-amino-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-trifluoromethyl-phenyl)-4-[2-(2-amino-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-hydroxy-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(1-piperazinyl)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-{2-(4-morpholinyl)-ethyl-amino}-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(4-morpholinyl)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-(2-n-propylamino-4-pyridyl)-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(n-1-butylamino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-(2-amino-4-pyridyl)-2-pyrimidine-amine, and -   N-(3-chloro-phenyl)-4-(2-dimethylamino-4-pyridyl)-2-pyrimidine-amine,     or a salt thereof.

Preferred is also a compound of the formula I selected from the compounds mentioned in tables 2, 4, 5, 8, 31, 33, 34 and 37, or a salt thereof, or the whole group of compounds mentioned in said table.

Especially preferred is a compound of the formula I selected from the compounds of formula I mentioned in table 59, or a salt thereof, or the whole group of compounds in that table, or a salt of any thereof, with the exception of

-   N-(3-chloro-phenyl)-4-[2-(3-hydroxy-propyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-hydroxy-propyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-imidazol-1-yl-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-(2-hydrazino-4-pyridyl)-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-amino-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(2-hydroxy-ethyl-amino)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(1-piperazinyl)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-{2-(4-morpholinyl)-ethyl-amino}-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-[2-(4-morpholinyl)-4-pyridyl]-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-(2-n-propylamino-4-pyridyl)-2-pyrimidine-amine, -   N-(3-chloro-phenyl)-4-(2-amino-4-pyridyl)-2-pyrimidine-amine, and -   N-(3-chloro-phenyl)-4-(2-dimethylamino-4-pyridyl)-2-pyrimidine-amine,     or a salt thereof.

The compounds useful according to the invention are prepared according to methods that are, per se, known in the art (this does mean, however, that, where novel compounds are produced, the respective process of manufacture is also novel) especially by reacting a compound of the formula (II),

-   (or a salt thereof) wherein X is a leaving group, especially halo,     for example fluoro, chloro, bromo or iodo, and the other moieties     have the meanings given for a compound of the formula I1, with a     hydrazino, amino or imino compound of the formula (III)     H—R₆  (III) -   (or a salt thereof) wherein R₆ has the meanings given for a compound     of the formula I under a) where hydrazino is unsubstituted or mono     to threefold substituted by optionally substituted alkyl, b), c)     where piperazinyl is bound via a nitrogen atom, d) where morpholinyl     is morpholino, or especially e), -   or by reacting a compound of the formula (IV)

-   wherein n and R₁ to R₅ have the meanings given for a compound of the     formula I and wherein R₆* is hydrogen or optionally substituted     alkyl as defined above, with a halogenide (Va) or an anhydride (Vb)     Hal-R₉  (Va)     O(R₉)₂  (Vb) -   wherein Hal is chloro, bromo or iodo, especially chloro or bromo and     R₉ has the meanings of the carboxyl, sulfoxyl and sulfonyl moieties     for a compound of the formula I under R₆=f), g), h) or i); -   or by reacting a compound of the formula IV with an acetal of an     amide (Vc), or any other form of an activated amide     (R₁₀)₂N—C(R₇)—(OR₁₁)₂  (Vc) -   wherein the term (R₁₀)₂N is R₈ as defined under formula I and R₁₁ is     alkyl or C(OR₁₁)₂ has the meaning of a cyclic acetal, such as     dioxolanyl or dioxanyl for a compound of the formula I under R₆=g),     wherein R₇ is hydrogen or alkyl, -   or by reacting a compound of the formula IV with a S-alkyl thiourea     derivative (Vd), or any other form of an activated urea     R ₁₀ N═C(R ₇)—SR ₁₁  (Vd) -   wherein the term R₁₀N is R₈ and R₁₁ is alkyl for a compound of the     formula I under R₆=g), wherein R₇ is amino, mono- or dialkylamino, -   or by reacting a compound of the formula IV with an aldehyde     analogue of an unsubstituted or substituted lower alkyl compound     that carries an aldehyde (—CHO) instead of the binding methylene     group (—CH₂—) of the corresponding unsubstituted or substituted     lower alkyl as described above as substituent R₆ “unsubstituted or     substituted mono- or di-(lower alkyl)amino” wherein the substituents     are as defined above in a final product of formula I in the presence     of a reducing agent, preferably sodium cyanoborohydride for a     compound of the formula I, wherein R₆ is mono- or di-(lower     alkyl)amino wherein the lower alkyl moieties are unsubstituted or     substituted by one or more substituents independently selected from     the group consisting of amino, N-mono- or N,N-di-(lower     alkyl)-amino, (lower alkoxy)-lower alk-oxy, lower     alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower     alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower     alkylamino, cyano, halogen, oxo bound to a carbon that is not     directly bound to a heteroatom, hydroximino, alkoximino, optionally     substituted hydrazono, lower alkenyl, lower alkynyl, guanidyl, lower     alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower     alkanoylamino, halo-lower alkanoylamino, lower     alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino,     lower alkoxy-lower alkylaminocarbonylamino, amidino,     di-lower-alkylamino-cyclohexyl, carboxy, lower alkoxycarbonyl,     hydroxy-lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl,     lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower     alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower     alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy,     lower alkoxy-lower alkanoyloxy, carbamoyl, N-mono- or N,N-di-lower     alkylcarbamoyl, N-(hydroxy-lower alkyl)carbamoyl, N-lower     alkyl-N-hydroxy-lower alkylcarbamoyl, N,N-di-(hydroxy-lower     alkyl)-carbamoyl, N-hydroxy-carbamoyl, hydroxy, lower alkoxy, lower     alkenyloxy, lower alkinyloxy, lower haloalkoxy, lower alkylthio,     lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxysilyl,     4-tetrahydro-4H-pyranyl, 3-pyrrolidinyl, 2- or 3-tetrahydrofuryl, 2-     or 3-dihydrofuryl, piperazinyl, lower alkanoyl-piperazinyl     (including formylpiperazinyl), optionally substituted heteroaryl and     optionally substituted heteroaryloxy; -   or (to obtain substituted hydrazino R₆ in accordance with the     definition under a) for a compound of formula I) by reacting a     compound of the formula (VI)

-   wherein n and R₁ to R₅ have the meanings given for a compound of the     formula I, with a halogenide (Va) or an anhydride (Vb)     Hal-R₉  (Va)     O(R₇)₉  (Vb) -   wherein Hal is chloro, bromo or iodo, especially chloro or bromo and     R₉ has the meanings of -   the acyl moiety for a compound of the formula I under R₆=a), -   or (to obtain substituted hydrazino R₆ in accordance with the     definition under a) for a compound of formula I) by reacting a     comound of the formula (VII a–d)

-   wherein n and R₁ to R₅ have the meanings given for a compound of the     formula I and R₉ has the meanings of the acyl moiety for a compound     of the formula I under R₆=a), with a halogenide of the formula     (VIII)     Hal-R₁₂  VIII -   wherein Hal is chloro, bromo or iodo, especially chloro or bromo and     R₁₂ has the meanings of the alkyl moiety for a compound of the     formula I under R₆=a), -   and, if desired, a compound of the formula I thus obtained is     converted into a salt thereof, or an obtained salt is converted into     a free compound and/or into a different salt, or a compound of     formula I is converted into a different compound of formula I, -   where functional groups in a starting material of the formula II     and/or III, where necessary, are present in protected form, and any     protecting groups present are removed in order to obtain the final     product.

The compounds of the formula I thus obtainable and the remaining compounds of the formula I can, mutatis mutandis, also be prepared in accordance with manufacturing processes described in WO 95/09853, or in analogy to the methods described therein—therefor WO 95/09853 is herewith incorporated by reference. Also appropriate protecting groups, their introduction and removal are described in WO 95/09853. The characteristic of protecting groups in the strict sense is that they are not present in the final compounds of formula I.

A compound of the formula II can be obtained preferably by reacting a compound of the formula (IX)

(or—if n is 0—a salt thereof) wherein L is a leaving group, especially alkoxy, such as lower alkoxy, esterified OH (especially tosyloxy), or di-(lower alkylamino), X is a leaving group (preferably halo, such as chloro, bromo or iodo) and the other moieties are defined as for a compound of the formula I, with a guanidino compound of the formula (XI),

(or a salt thereof) wherein R₁ is as defined for a compound of the formula I.

The reaction preferably takes place under conditions analogous to those mentioned in PCT application WO 95/09583, that is, in a suitable solvent or dispersing agent, for example a suitable alcohol, such as isopropanpol, or 2-butanol, at a temperature from room temperature (approximately 20° C.) to 150° C., e.g. under reflux.

The compound of the formula (IX) are known or can be obtained in accordance with methods that are known in the art, e.g. by reacting a compound of the formula (XII),

wherein the moieties R₂, R₃, R₃ and R₅ have the meanings given for a compound of the formula I and wherein X is a leaving group, preferably as defined for a compound of the formula (IX), either (i) under Claisen or analogue condensation reaction conditions (leading to a free hydroxy instead of the leaving group L in a compound of the formula IV; this free hydroxy group can then be converted into a leaving group, for example by ether formation with an alkylalkohol (“Alkoxy-H”;), yielding alkoxy as L, such as lower alkoxy, or by reaction with an acid or an active ester derivative, e.g. an acid chloride, yielding esterified OH (especially tosyloxy); or to alkoxy L, depending on the reaction conditions), or (ii) preferably by reaction with an N,N-di-(lower alkyl)-formamide di-lower alkylacetal, especially N,N-di-(methyl)formamide di-methylacetal, analogous to the procedure described in European Patent Application EP 0 233 461, which is incorporated by reference, e.g. by reaction in the respective N,N-di-(lower alkyl)-formamide di-lower alkylacetal at a temperature between room temperature and the boiling point of the reaction mixture, especially under reflux conditions.

An intermediate of the formula (XII) can, for example, be obtained by reaction of a metallated alkyl derivative of the formula (XIII), R₂—CH₂-Metal  (XIII) wherein R₂ is as defined for a compound of the formula I (preferably it is hydrogen or alkyl) and Metal stands preferably for Mg—Hal (Hal=halogen) or Li, with a pyridine acid derivative of the formula (XIV),

wherein R₃ to R₅ have the meanings given for a compound of the formula I, X is a leaving group, preferably as defined for a compound of the formula (II), and Y is a leaving group, preferably N-lower alkyl-N-lower alkoxy-amino or halogen, under standard conditions for alkylation reactions.

Alternatively, an intermediate of the formula (XII), wherein n is 0, can be obtained by reaction of a metallated pyridine derivative of the formula (XV),

wherein R₃ to R₅ have the meanings given for a compound of the formula I, X is a leaving group, preferably as defined for a compound of the formula (IX), and Metal stands for Mg—Hal (Hal=halogen) or Li, under standard conditions for alkylation reactions with an acyl equivalent of the formula (XVI),

wherein R₂ is as defined for a compound of formula I and Z is halo, or forms with the rest of the molecule an amide, an alkoxyamide, an anhydride or the like; or Z is hydrogen (meaning that the compound (XVI) is an aldehyde), resulting after the reaction in an alcohol that is then oxidised with a selective oxidant, for example in the presence of oxalylchloride and dimethyl sulfoxide, to the ketone intermediate of the formula (XII).

A starting material of the formula III is known, can be prepared by methods known in the art or is commercially available.

A starting material of the formula (XI) can be prepared (preferably obtaining an acid addition salt) by reaction of an aniline derivative of the formula (XVII),

wherein R₁ is as defined for a compound of formula I, with cyanamide (NC—NH₂) in a suitable solvent, e.g. an alcohol, such as a lower alkanol, for example (i) in the presence of equimolar amounts of the salt-forming acid, for example nitric acid, or (ii) in the presence of a clear, for example 60%, excess of a mineral acid, such as hydrochloric acid, where an ammonium salt of the desired salt-forming acid is added when the reaction is complete; at a temperature between room temperature and 150° C., e.g. under reflux.

Compounds of the formulae XIII, XIV, XV and XVI can be prepared according to methods that are known in the art.

The synthesis of many of the starting materials and intermediates can also be done as described in or in analogy to the processes described in WO 95/09853.

In all intermediates, functional groups that shall not participate in the reaction can be protected and deprotected at appropriate stages in order to avoid side reactions—appropriate protecting groups, their introduction and removal can be found e.g. in WO 95/09853.

The present invention also relates to novel starting materials and/or intermediates and to processes for the preparation thereof. The starting materials used and the reaction conditions chosen are preferably such that the compounds shown in this disclosure as being especially preferred or to be used preferably are obtained. Especially preferred among the process conditions are those described in the examples below, or analogous procedures.

The invention also relates to compositions which comprise the compounds of the formula I, or a salt thereof, as an active component, in particular plant-protecting compositions, and also to their use in the agricultural sector or related areas.

Active compounds of the formula I are customarily used in the form of compositions and may be added, simultaneously or successively, to the surface or plant to be treated together with additional active compounds. These additional active compounds may be either fertilizers, trace element-supplying agents or other preparations which influence plant growth. It is also possible, in this context, to use selective herbicides, such as insecticides, fungicides, bactericides, nematicides or molluscicides, or mixtures of several of these preparations, additionally, where appropriate, together with excipients, surfactants or other administration-promoting additives which are customary in formulation technology (designated collectively as carrier materials herein).

Suitable excipients and additives may be solid or liquid and are those substances which are appropriate in formulation technology, for example natural or regenerated minerals, solvents, dispersants, wetting agents, adhesives, thickening agents, binding agents or fertilizers.

A preferred method for applying a compound of formula I, or an agrochemical composition which comprises at least one of these compounds, is administration to the leaves (foliar application). The frequency and rate of aministration depend upon the risk of infestation by the corresponding pathogen. The compounds of formula II can, however, also penetrate the plant through the roots via the soil (systemic action). If the locus of the plant is impregnated with a liquid formulation or if the substances are introduced in solid form into the soil, e.g. in the form of granules (soil application). In paddy rice crops, such granules can be applied in metered amounts to the flooded rice fields. In order to treat seeds, the compounds of formula I can, however, also be applied to the seeds (coating), either by impregnating the grains or tubers with a liquid formulation of the active ingredient, or by coating them with a solid formulation.

Advantageous rates of application are in normally from 5 g to 2 kg of active ingredient (a.i.) per hectare (ha), preferably from 10 g to 1 kg of a.i./ha, especially from 20 g to 600 g a.i./ha. When the compound are used as seed dressings, dosages of from 10 mg to 1 g of active ingredient per kg seed are advantageous employed. The agrochemical compositions generally comprise 0.1 to 99% by weight, preferably 0.1 to 95% by weight, of a compound of formula I, 99.9 to 1% by weight, preferably 99.8 to 5% by weight, of a solid or liquid adjuvant and 0 to 25% by weight, preferably 0.1 to 25% by weight, of a surfactant. Whereas commercial products will preferably be formulated as concentrates, the end user will normally employ dilute formulations.

The compositions may also comprise further auxiliaries, such as stabilizers, antifoams, viscosity regulators, binders or tackifiers, as well as fertilizers or other active ingredients for obtaining special effects.

EXAMPLES

The subsequent examples are intended to illustrate the invention, without affecting the scope thereof.

Preparative Examples Synthesis Example 1 (3-Chloro-phenyl)-{4-[2-(2-methoxy-1-methyl-ethylamino)-pyridin-4-yl]-pyrimidin-2-yl}-amine

A mixture of (3-chloro-phenyl)-[4-(2-chloro-pyridin-4-yl)-pyrimidin-2-yl]-amine (10.0 g, 0.03 mol) and 2-amino-1-methoxypropane (14.0 g, 0.16 mol) in dioxane (75 ml) is heated in an autoclave at 195° C. for 12 hours. The reaction mixture is partitioned between ethyl acetate and water. The organic phase is separated, dried over magnesium sulfate, filtered and evaporated under reduced presssure. The residue is purified by silicagel chromatography to give the title compound, m.p. 143–144° C.

Synthesis Example 2 (3-Chloro-phenyl)-[4-(2-hydrazino-pyridin-4-yl)-pyrimidin-2-yl]-amine

A mixture of (3-chloro-phenyl)-[4-(2-chloro-pyridin-4-yl)-pyrimidin-2-yl]-amine (4.8 g, 0.015 mol) in hydrazine (20 ml, 0.41 mol) is refluxed for 90 minutes. The reaction is poured into ethanol (300 ml) with efficient stirring. The resulting precipitate is filtered with suction to yield the title compound, m.p. 201–203° C.

Synthesis Example 3 {4-[2-(1-Acetoxybutyl-2-amino)-pyridin-4-yl]-pyrimidin-2-yl}-(3-chloro-phenyl)-amine

Step 1:

A mixture of (3-chloro-phenyl)-[4-(2-chloro-pyridin-4-yl)-pyrimidin-2-yl]-amine (10.0 g, 0.03 mol) and 2-amino-1-hydroxybutane (30.0 g, 0.3 mol) is heated at 180° C. for 18 hours. The reaction mixture is partitioned between ethyl acetate and water. The organic phase is separated, dried over magnesium sulfate, filtered and evaporated under reduced presssure. The residue is purified by silicagel chromatography to give the title compound, m.p. 99–101° C.

Step 2:

{4-[2-(1-Hydroxybutyl-2-amino)-pyridin-4-yl]-pyrimidin-2-yl}-(3-chloro-phenyl)-amine (1.24 g, 3.3 mmol) and acetic anhydride (0.41 g, 4.0 mmol) are refluxed in dimethoxyethane (20 ml) in the presence of a catalytic amount of DMAP for 30 minutes. The reaction mixture is evaporated under reduced pressure. The residue is crystallized by adding crushed ice. The solid is filtered and dried to give the title compound, m.p. 125–126° C.

Synthesis Example 4 {4-[3-Chloro-2-(2-methoxy-ethylamino)-pyridin-4-yl]-pyrimidin-2-yl}-(3-chloro-phenyl)-amine

Step 1:

A solution of 2,3-dichloropyridine (7.4 g, 0.05 mol) in THF (15 ml) is added at −60° C. to a solution of lithium diisopropylamine (0.07 mmol) in THF/hexane (1:1, 100 ml). After stirring for one hour at the same temperature a cooled solution of acetaldehyde in THF (8 ml) is added dropwise. The reaction mixture is allowed to warm to −20° C. and is then quenched with an aqueous saturated solution of ammonium chloride. The organic phase is separated, dried over magnesium sulfate, filtered and evaporated under reduced pressure to give a clear oil, that is used in the next step without further purification.

Step 2 (Swern Oxidation):

The product described under step 1 is added carefully at −60° C. to a solution prepared from oxalyl chloride (6.0 ml, 0.07 mol) and dimethylsulfoxide (8.5 ml, 0.12 mol) in methylene chloride (150 ml) at the same temperature. After stirring the reaction mixture for 30 minutes at −60° C. triethylamine (49 ml, 0.35 mol) is added and then allowed to reach room temperature. Brine is added and the methylene chloride is evaporated under reduced pressure. The product is extracted with ether, dried over magnesium sulfate, filtered and distilled under reduced pressure to give the product as a colorless oil, b.p. 90–93/2 mm.

Step 3:

The product described under step 2 is refluxed in dimethylformamide diethylacetal (15 ml) for 15 minutes. The still hot reaction mixture is diluted with hexane and the resulting crystalline product filtered. This intermediate is refluxed with 3-chlorophenylguanidine hydrogencarbonate (11.5 g, 0.05 mol) in 2-butanol (200 ml) for 14 hours. Diluting the reaction mixture with hexane and filtering gives the intermediate in form of yellow crystals.

Step 4:

The product prepared in step 3 (1.0 g, 2.8 mmol) is refluxed in 2-methoxyethylamine (5 ml) for 8 hours. The reaction mixture is partitioned between ethyl acetate and water. The organic phase is separated, dried, filtered and evaporated under reduced pressure to give the title compound, m.p. 172° C.

Synthesis Example 5 {4-[2-Chloro-6-(2-methoxy-1-methyl-ethylamino)-pyridin-4-yl]-pyrimidin-2-yl}-(3-chloro-phenyl)-amino

Step 1:

A suspension of 2,6-dichloroisonicotinic acid (20.0 g, 0.10 mol) and oxalylchloride (11.2 ml, 0.13 mol) in methylenechloride (100 ml) is stirred at room temperature in the presence of a katalytic amount of dimethylformamide for 2 hours to give a clear solution. The solvent is evaporated under reduced pressure and the residue is added to a well stirred solution of N,O-dimethylhydroxylamine (12.0 g, 0.2 mol) and triethylamine (10.2 g, 0.1 mol) at 0–5° C. After stirring for 2 hours at room temperature the reaction mixture is washed with water. The organic phase is dried over magnesium sulfate, filtered and evaporated under reduced pressure to give 2,6-dichloro-N-methoxy-N-methyl-isonicotinamide in form of colorless crystals, m.p. 69–70° C.

Step 2:

To a solution of 2,6-dichloro-N-methoxy-N-methyl-isonicotinamide (20 g, 0.085 mol) in THF (150 ml) is added at −30° C. a solution of methyl magnesium chloride in THF (0.2 mol) at such a rate that the temperature does not exceed −20° C. After stirring the mixture for an additional hour at −20° C. the mixture is poured on an aqueous, saturated solution of ammonium chloride. The organic phase is separated, dried over magnesium sulfate, filtered and evaporated to dryness.

Step 3:

The crystalline product obtained in step 2 is refluxed in dimethylformamide diethyl acetal (20 ml) for 10 minutes. The reaction mixture is evaporated under reduced pressure to give a dark red oil. The intermediate is refluxed with 3-chlorophenylguanidine hydrogencarbonate (16.2 g, 0.07 mol) in 2-butanol (250 ml) for 1 hour. The product is crystallizing during this time. The crystals are filtered and washed with ether: yellow crystals, m.p. 239–240° C.

Step 4:

The intermediate obtained in step 3 (0.5 g, 1.4 mmol) in 1-methoxy-2-aminopropane (2 ml) is refluxed for 16 hours. The crude product mixture is purified by flash column chromatography to give the crystalline title compound, m.p. 128–129° C.

Synthesis Example 6 [4-(2-Amino-pyridin-4-yl)-pyrimidin-2-yl]-(3-chloro-phenyl)-amine

A suspension of (3-chloro-phenyl)-[4-(2-chloro-pyridin-4-yl)-pyrimidin-2-yl]-amine (10.0 g, 0.03 mol) in dioxane (150 ml) and ammonia (20 g) is heated in an autoclave at 200° C. for 48 hours. The reaction mixture is partitioned between ethyl acetate and water. The organic phase is evaporated under reduced pressure and the product is purified by chromatography on silicagel.

Synthesis Example 7 N′-{4-[2-(3-Chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-.N.,.N.-dimethyl-formamidine

A mixture of [4-(2-amino-pyridin-4-yl)-pyrimidin-2-yl]-(3-chloro-phenyl)-amine (0.3 g, 1 mmol) and N,N-dimethylformamid diethylacetal (0.3 g, 2 mmol) are heated in dimethylformamide (5 ml) at 120° C. for 1 hour. The temperature is raised to 140° C. and the liberated ethanol is allowed to distill of. After cooling the reaction mixture to room temperature, diethylether is added and the resulting crystals are filtered with suction to give the title compound, m.p. 194–195° C.

Synthesis Example 8 N-{4-[2-(3-Chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-yl}-propionamide

Propionic acid anhydride (0.26 g, 2.0 mmol) is added to a solution of [4-(2-amino-pyridin-4-yl)-pyrimidin-2-yl]-(3-chloro-phenyl)-amine (0.5 g, 1.68 mmol) and a catalytic amount of DMAP in dimethoxyethane (10 ml) at 95° C. Heating is continued for 1 hour. On cooling the products starts to crystallize. Diethylether is added and the product is filtered of and washed with ether to give the title compound, m.p. 215–216° C.

Synthesis Example 9 {4-[2-(3-Chloro-phenylamino)-pyrimidin-4-yl]-pyridin-2-ylamino}-acetic acid

A mixture of (3-chloro-phenyl)-[4-(2-chloro-pyridin-4-yl)-pyrimidin-2-yl]-amine (10.0 g, 0.03 mol) and glycine (4.8 g, 0.06 ml) in DBU (100 ml) is heated at 150° C. under an atmosphere of argon for 40 hours. The still hot reaction mixture is poured into water. After washing the aqueous phase with ethyl acetate the pH is adjusted to 5 by adding citric acid. The resulting precipiate is filtered and recrystallized from dimethylformamide/ethanol to give the product in form of yellow crystals, m.p. 136–138° C. (with decomposition).

Synthesis Example 10 [4-(2-Allylamino-1-oxy-pyridin-4-yl)-pyrimidin-2-yl]-(3-chloro-phenyl)-amine

To a suspension of [4-(2-allylamino-pyridin-4-yl)-pyrimidin-2-yl]-(3-chloro-phenyl)-amine (1.0 g, 3 mmol) in methylene chloride (10 ml) is added a solution of m-chloroperbenzoic acid (0.73 g, 70%, 3 mmol) in methylen chloride (5 ml) at 5° C. The reaction mixture is stirred at room temperature for 30 minutes, washed with bicarbonate solution and evaporated under reduced pressure. The residue is purified by chromatography to give the title compound, m.p. 223–224° C.

Synthesis Example 11 (3-Chloro-phenyl)-{4-[2-(ethyl-methoxymethyl-amino)-pyridin-4-yl]-pyrimidin-2-yl}-amine

Solid potassium-t-butoxide (0.27 g, 2.5 mmol) is added at room temperature to a solution of (3-chloro-phenyl)-[4-(2-ethylamino-pyridin-4-yl)-pyrimidin-2-yl]-amine (0.5 g,1.5 mmol) in dry tetrahydrofurane (15 ml). The resulting solution is cooled to 0° C. and chloromethylmethylether (0.16 g, 2.0 mmol) is added at such a rate that the temperature does not exceed 5° C. After stirring the mixture for 2 hours at room temperature, the solvent is evaporated under reduced pressure and the product is purified by chromatography. The product is obtained in form of slightly yellow crystals, m.p. 114–115° C.

Analogously to the above examples the compounds of tables 1 to 58 and those of the following table 59 may be prepared.

TABLE 59

Addition CN R1 R2 R3 R4 R5 R6 Salt m.p. 1. Cl H H H H NHCH₂CH₂NH₂ 151–156 2. Cl H H H H NH-(3-tetrahydrofuryl) 184–185 3. Cl H H H H NHCH₂COOH 136–138 4. Cl H H H H NHCH(CH₂CH₃)CH₂OCH₃ Oil 5. OCF₂CHF₂ H H H H NHCH(CH₃)CH₂OCH₃ 116–117 6. Cl H H H Cl NHCH₂CH₂OCH₃ 172 7. Cl H F H H NHCH(CH₃)CH₂OCH₃ 103–105 8. Cl H H H H NHCH₂CH₂CH₂-(4-morpholinyl) 187–188 9. Cl H H Cl F NHCH(CH₃)CH₂OCH₃ 100–101 10. Cl CH₃ Cl H H NHCH(CH₃)CH₂OCH₃ 100–101 11. Cl H Cl H H NHCH(CH₃)CH₂OCH₃ 128–129 12. Cl H H H H NHCH(CH₃)CH₂OCH₃ HCl 104–105 (d) 13. Cl H H H H NHCH(CH₃)CH₂OCH₃ Citric 80–90 (d) acid 14. Cl H H H H NHCH(CH₃)CH₂OCH₃ PhSO3H 103–104 (d) 15. Cl H H H H NHCH(CH₃)CH₂OCH₃ MeSO3H 111–112 (d) 16. Cl H H H H NHCH(CH₃)CH₂CH₂-(1-imidazolyl) 150–151 17. Cl H H H H 4-morpholinyl 175–176 18. Cl H H H H NH-(1-amino-2-cyclohexyl) >215 19. Cl H H H H NHCH(CH₃)CH₂CH₂N(CH₃)₂ 147–148 20. Cl H H H H NHCH₂CH₂-(4-morpholinyl) 171–172 21. Cl H H H H 1-piperazinyl 103–104 22. Cl H H H H NHNH₂ 201–203 23. Cl H H H H NHC(CH₃)₂CH₂CH₂OH 129–130 24. Cl H H H H NHC(CH₃)₂CH₂CH₂OCH₃ 25. Cl H H H H NHC(CH₃)₂CH₂CH₂OCH₂CH₃ 26. Cl H H H H NHCH₂CH₂OCH₂CH₃ Oil 27. Cl H H H H NHCH(CH₂CH₂CH₃)CH₂OH 63–64 28. Cl H H H H NHC(CH₃)₂CH₂OH 139–140 29. Cl H H H H NHCH₂CH(CH₃)OCH₃ 30. Cl H H H H NH CH₂CH(CH₃)CH₂-(1-imidazolyl) 203–204 31. Cl H H H H NHCH(CH₂CH₃)CH₂OH 90–91 32. Cl H H H H NHCH(CH₃)CH₂OCH₃ 143–144 33. Cl H H H H NHCH₂CH₂-(1-imidazolyl) 34. Cl H H H H NHCH₂CH₂OCH₃ 161–162 35. Cl H H H H NHCH(CH₂OH)₂ 129–130 36. Cl H H H H NHCH₂CH₂CH(CH₃)-(1-imidazolyl) 130 37. Cl H H H H NHCH₂CH₂OH 190–191 38. Cl H H H H N(CH₂OCH₃)CH(CH₃)CH₂OCH₂OCH₃) oil 39. Cl H H H H NHCH(CH₃)CH₂OH 83–85 40. Cl H H H H NHC(CH₃)₂CH₂OCH₃ 109 41. Cl H H H H NHCH(CH[CH₃]CH₂CH₃)CH₂OH oil 42. Cl H H H H NHCH₂CH₂CH₂NH₂ 140 43. Cl H H H H NHCH₂CH₂CH₂-(1-imidazolyl) 176–177 44. Cl H H H H NHCH₂CH₂-(1,2,4)-triazol-1-yl 45. Cl H H H H NHCH₂CH₂CH₂NHCOOCH₂CH₃ 150–151 46. Cl H H H H NHCH₂CH₂CH₂OH 135–142 47. Cl H H H H NHCH₂CH₂CH₂OCH₃ 48. Cl H H H H NHCH₂CH₂CH₂NH₂ MeSO₃H 49. Cl H H H H NHCH₂CH₂CH₂-(1-imidazolyl) MeSO₃H 50. Cl H H H H NHCH(CH₃)CH₂Oac 137–138 51. Cl H H H H NHCH(CH₂CH₃)CH₂OAc 125–126 52. Cl H H H H NHCH₂CH₂OAc 128–129 53. Cl H H H H NHCH(CH₂CH₂CH₃)CH₂OAc oil 54. Cl H H H H NHCH(CH₃)CH₂OCH₂CH₃ 55. Cl H H H H NHCH(CH₃)CH(CH₃)OCH₃ 56. Cl H H H H NHCH₂CH(CH₃)OCH₃ 57. Cl H H H H NHCH₂CH₂OCH₂OCH₃ 58. Cl H H H H NH₂ 214–215 59. Cl H H H H N(CH₃)₂ 178–179 60. Cl H H H H NHCH₂CH₃ 201 61. Cl H H H H NHCOCH₃ 245–247 62. Cl H H H H NHCOCH₂CH₂CH₂CH₃ 185–186 63. Cl H H H H NHCOCF₃ 180–181 64. Cl H H H H NHCH₃ 196–197 65. Cl H H H H NHCH(CH₃)CH(OCH₃)₂ 121–122 66. Cl H H H H N═C(CH₃)N(CH₃)₂ Oil* 67. Cl H H H H NHCH₂CH₂CH₂CH₃ 165–166 68. Cl H H H H NHCH(CH₃)₂ 184–185 69. Cl H H H H NHCH₂CH═CH₂ 179–180 70. Cl H H H H NHC(CH₃)₃ 125–126 71. Cl H H H H NHCH(CH₃)CH₂CH₂-(2-pyridyl) 136–137 72. Cl H H H H N(CH₃)NH₂ 181–183 73. Cl H H H H NHCH₂CH₂SO₂CH₃ 164–165 74. Cl H H H H NHCH₂CH₂SOCH₃ 167–168 75. Cl H H H H NHCH₂-(2-tetrahydrofuryl) 151–152 76. Cl H H H H NHCH₂CH(CH₃)OH 152–153 77. Cl H H H H NHCOCH(OH)CH₃ 169–170 78. Cl H H H H NHCH₂-(2-furyl) 185–186 79. Cl H H H H NHCH₂-(2-pyridyl) 145–146 80. Cl H H H H NH-(3-pyrrolidyl) 129–130 81. Cl H H H H NHCH₂CH═C(CH₃)₂ 141–143 82. Cl H H H H NHCH(CH₃)₂ HCl 88–89 83. Cl H H H H NH-(4-tetrahydropyranyl) 166–167 84. Cl H H H H NHCH₂-(3-tetrahydrofuryl) 184–185 85. Cl H H H H NHCH₂CH(CH)₃CH₂CH₃ 162–164 86. Cl H H H H NHCH₂CH₂OCH₂CH₃ 123–124 87. Cl H H H H NHCH₂CH(OCH₃)₂ 148–149 88. Cl H H H H NCH₃NHCH₃ 89. Cl H H H H NHCH₂CH₂NHCOOCH₂CH₃ 148–150 90. Cl H H H H NHCH₂CH₂-(2-pyridyl) 164–165 91. Cl H H H H N(CH₃)CH₂OCH₃ 92. Cl H H H H NHCOCF₂CF₂CF₃ 149–150 93. Cl H H H H NHCOCF₂CF₃ 172–174 94. Cl H H H H NHCH₂CH₂CH₂O-(2-pyrimidinyl) 93–95 95. Cl H H H H NHCH(CH₃)CH₂O-(2-pyrimidinyl) 79–80 96. Cl H H H H NHCOCH₂CH₃ 215–216 97. Cl H H H H N═CHN(CH₃)₂ 194–195 98. Cl H H H H N(CH₂CH₃)CH₂OCH₃ 114–115 99. Cl H H H H NHCH(CH₃)CH₂CH₃ 198–199 100. Cl H H H H NHCH₂CH₂CH₂Si(OCH₃)₃ 144–146 101. Cl H H H H N(NH₂) CH₂CH₂OH 102. Cl H H H H NHCH₂-(3-pyridyl) 166–167 103. Cl H H H H NHCH₂CF₃ 222–223 104. Cl H H H H N(CH₃)N(Ac)₂ 197–199 105. Cl H H H H N(CH₃)NHAc 210–212 106. Cl H H H H NHCH₂CH₂CH₂OCOCH₂CH₃ 107. Cl H H H H NHCH(CH₃)CH₂SCH₃ 149–150 108. Cl H H H H NHCH₂CH₂SCH₃ 148–149 109. Cl H H H H NHCH(CH₃)CH₂SOCH₃ 110. Cl H H H H N═C(CH₃)N(CH₂CH₃)₂ 111. Cl H H H H N═C(CH₃)N(CH₃)CH₂CH₃ 112. Cl H H H H N═C(CH₃)N(CH₂CH₃)₂ 113. Cl H H H H NHS(O)N(CH₃)₂ 114. Cl H H H H NHC(O)N(CH₃)₂ 115. Cl H H H H NHCH(CH₃)C═CHCH₃ 116. Cl H H H H NHCH(CH₃)C═C(CH₃)₂ 117. Cl H H H H NHCH₂C≡CH 118. Cl H H H H NHCH(CH₃)C≡CH 119. Cl H H H H NHCON(CH₂CH₃)₂ 120. Cl H H H H NHCOOCH₃ 121. Cl H H H H NHCOOCH₂CH₃ 247–248 122. Cl H H H H N═C(NH₂)NH₂ 123. Cl H H H H N═CHN(CH₂CH₃)₂ 124. Cl H H H H NHC(CH₃)₂CH₂SCH₃ 125. Cl H H H H NH-(3-tetrahydrofuryl) HCl 215–216 126. Cl H H H H NHCH₂-(3-furyl) 174–177 127. Cl H H H H NHCH(CH₃)₂ MeSO₃H 128. Cl H H H H NHCH(CH₃)₂ Cltric acid 129. Cl H H H H

138–139 130. Cl H H H H NHCH₂CH(CH₂CH₃)CH₂CH₂CH₂CH₃ 140–141 131. Cl H H H H NHCH₂CH₂-(4-imidazolyl) Tartaric solid acid 132. Cl H H H H NHCH₂CH₂C(CH₃)₂OH solid 133. Cl H H H H NHCH₂CH₂CO (1-[4- ETHYLPIPERAZINYL]) 134. Cl H H H H

solid 135. Cl H H H H

solid 136. Cl H H H H NHCH₂CH₂COOMe solid 137. Cl H H H H

solid 138. Cl H H H H NHCH₂CH₂CONHC(CH₃)₃ solid 139. Cl H H H H NHCH₂CH₂CONHCH₂CH₃ solid 140. Cl H H H H NHCH₂CH₂CONH(CH₂CH₃)₂ solid 141. Cl H H H H NHCH₂CH₂COOCH(CH₃)₂ solid 142. Cl H H H H

solid 143. Cl H H H H

solid 144. Cl H H H H

solid 145. Cl H H H H NHCH₂CH₂COOCH₂CH₃ solid 146. Cl H H H H NHCH₂CH₂CH₂COOH solid 147. Cl H H H H NHCH₂CH₂-(2-thienyl) solid 148. Cl H H H H N(CH₃)CH₂CH₂NH₂ solid 149. Cl H H H H NHCH₂CH₂N(CH(CH3)₂)₂ solid 150. Cl H H H H NHCH₂CH₂CONHOCH₃ solid 151. Cl H H H H NHCH₂CH₂CH₂CH₂NH₂ solid 152. Cl H H H H NHCH₂CH₂SO₃H solid 153. Cl H H H H NHCH₂CH₂NHCH₃ MeSO3H solid 154. Cl H H H H NHCH₂CH₂NH₂ MeSO3H solid 155. Cl H H H H

solid 156. Cl H H H H NHCH₂CH₂NHCH(CH₃)₂ solid 157. Cl H H H H NHCH₂CH₂NHCH₂CH₃ MeSO3H solid 158. Cl H H H H NHCH₂CH₂CH₂(4-triazolyl) MeSO3H solid 159. Cl H H H H NH-cyclohexyl 191–192 160. Cl H H H H

240–241 161. Cl H H H H NHCH₂CH₂CH₂NHCOCF₃ solid 162. Cl H H H H NHCH₂CH₂CH₂NH(2-pyrimidyl) 186–188 163. Cl H H H H NHCH₂CH₂CH₂NHCOCH₂CH₃ 171–172 164. Cl H H H H NHCH₂CH₃ MeSO3H solid 165. Cl H H H H NHCH(CH₃)CH₂OCOOCH₂CH₃ 102–103 166. Cl H H H H NHCH₂CH₂CH₂(1-triazolyl) 149–150 167. Cl H H H H

90–91 168. Cl H H H H

139–140 169. Cl H H H H N(CH₃)CH₂OCH₃ 170. Cl H H H H NHCH₂CH₂CH₃ Cl H H H H

214–215 171. Cl H H H H

solid 172. Cl H H H H

oil 173. Cl H H Cl F N(CH₃)₂ 138–139 174. Cl H H H Cl N(CH₃)₂ 165–167 175. Cl H F H H NHCH(CH₃)₂ 174–175 176. Cl H H H H

143–144 177. Cl H H H H

178–179 178. Cl H H H H

123–124 179. Cl H H H H

119–120 180. Cl H H H H NH(CH₂)₅CO₂CH₃ 112–115 181. Cl H H H H NHCH(CH₃)CH₂OCO₂CH₃ 112–113 182. Cl H H H H NHNHCOCH₃ 205 183. Cl H H H H NHCH(CH₃)CO₂CH₃ oil 184. Cl H H H H NHCH₂CH₂C(CH₃)₃ 176–178 185. Cl H H H H NHCH₂CH₂CH(CH₃)CH₂C(CH₃)₃ 155–156 186. Cl H H H H NHCH(CH₃)CH₂OCHO 119–121 187. Cl H H H H NHCOCH₂OCH₃ 164 188. Cl H H H H NHSO₂CH₃ 245 189. Cl H H H H NHCH(CH₃)CO₂CH(CH₃)₂ oil 190. Cl H H H H N[(CH₂)₃OCO₂CH₂CH₃]CO₂CH₂CH₃ solid 191. Cl H H H H CH₂CH₂COOH 192. Cl H H H H NHCH₂CH₂NHCH₂CH₃ 193. Cl H H H H NHCH₂CH₂CH₂-(1,2,4)-triazol-1 -yl 194. Cl H H H H NHCH₂CO₂CH₃ 164 195. Cl H H H H NHCH(CH₃)CO₂CH₂CH₃ oil 196. Cl H H H H NHCH₂CH(CH₃)CO₂CH₂CH₃ oil 197. Cl H H H H

155–161 198. Cl H H H H

193–197 199. Cl H H H H NHCH₂CH(CH₃)CO₂CH₃ oil 200. Cl H H H H NHCH₂CH₂CH(OH)CH(OH)CH₂OH 133–139 201. Cl H H H H NHCH(CH₃)CO₂CH₂CH₃ 136–137 202. Cl H H H H NHCH₂CONHCH₃ 191–192 203. Cl H H H H NHCH(CH₃)CONHCH₃ 205 204. Cl H H H H NH(CH₂)₄OH 205. Cl H H H H

206. Cl H H H H NH(CH₂)₃NHCH₂CH₂OH 207. Cl H H H H NHCH₂CH₂-(4-imidazolyl) 208. Cl H H H H NH(CH₂)₅OH 209. Cl H H H H N[(CH₂)₃OCONH₂]CONH₂ 210. Cl H H H H N(CH₃)CH₂CH₂OH 211. Cl H H H H N(CH₂CH₂OH)₂ 212. Cl H H H H

213. Cl H H H H NH(CH₂)₃OCH(CH₃)₂ 214. Cl H H H H NH(CH₂)₃N(CH₃)₂ 215. Cl H H H H NH(CH₂)₃OCH₂CH₃ 216. Cl H H H H

217. Cl H H H H NHCH₂-(4-pyridyl) 218. Cl H H H H NHCH₂CH₂-(1-piperidinyl) 219. Cl H H H H NH(CH₂)₃N(CH₂CH₃)₂ 220. Cl H H H H NH(CH₂)₂N(CH₂CH₃)₂ 221. Cl H H H H NH(CH₂)₂N(CH₃)₂ 222. Cl H H H H NHCH₂CH₂-(1-pyrrolidinyl) 223. Cl H H H H NHCH₂CH₂CONH₂ 224. Cl H H H H NHCH₂CH₂CON(CH₃)₂ 225. Cl H H H H

226. Cl H H H H NHCH₂CH₂CONHCH₂CH₂CH₃ 227. Cl H H H H NHCH₂CH₂CONHCH₂Ph 228. Cl H H H H NHCH₂CH₂CONH(c-Hexyl) 229. Cl H H H H

230. Cl H H H H NHCH₂CON(CH₂CH₃)₂ 231. Cl H H H H

232. Cl H H H H NHCH₂CH₂CONHOH 233. Cl H H H H NHCH₂CH₂NHCH₃ 234. Cl H H H H NHCH₂CH₂CH₂NHSO₂CH₃ 235. Cl H H H H NHCH₂CH₂CH₂NHCOCH₃ 236. Cl H H H H NHCH₂CH₂CH₂NHCOOH(CH₃)₂ 237. Cl H H H H NHCH₂CH₂CH₂NHCONH₂ 238. Cl H H H H NHCH(CH₃)CONHCH₂CH₃ 173–174 239. Cl H H H H

130 240. Cl H H H H NHCH(CH₃)CH₂OH 122–123 241. Cl H H H H N(COCF₃)CH(CH₃)CH₂OCH₃ oil 242. Cl H H H H N(CO₂CH₃)CH(CH₃)CH₂OCH₃ 243. Cl H H H H N(CHO)N(CH₃)CO₂C(CH₃)₃ solid 244. Cl H H H H NHN(CH₃)COCH₃ solid 245. Cl H H H H NHCH₂CH₂NHAc 246. Cl H H H H NHCH₂CH₂-(3-pyridyl) 247. Cl H H H H NH(CH₂)₃OH MeSO₃H 248. Cl H H H H NHCH₂CH₂COOH Na 249. Cl H H H H NH(CH₂)₃NHCH₂CH₂OH MeSO₃H 250. Cl H H H H NHCH₂CH₂-(1-imidazolyl) MeSO₃H 251. Cl H H H H NHCH₂CH₂NHCH(CH₃)₂ MeSO₃H 252. Cl H H H H

253. Cl H H H H

254. Br H H H H NH(CH₂)₃OH 144–146 255. Br H H H H NH(CH₂)₃OCH₃ 132–134 256. F H H H H NH(CH₂)₃OH 153–156 257. CH₃ H H H H NH(CH₂)₃OH 128–130 258. CF₃ H H H H NH(CH₂)₃OH 155–156 259. CH₃O H H H H NH(CH₂)₃OH 126–129 260. CH₃S H H H H NH(CH₂)₃OH  98–1 00 261. NO₂ H H H H NH(CH₂)₃OH 152–155 262. Ac H H H H NH(CH₂)₃OH 125–128 263. CF₃ H H H H NH(CH₂)₃OCH₃ 144–147 264. ClCF₂O H H H H NHCH(CH₃)CH₂OCH₃ 265. ClCF₂O H H H H NHCH₂CH₂OH 151–153 266. OCF₂CHF₂ H H H H NH(CH₂)₃OH 267. OCF₂CHF₂ H H H H NH(CH₂)₃OCH₃ 268. CF₃ H H H H NH(CH₂)₂NH₂ 269. OCF₂CHF₂ H H H H NH(CH₂)₄NH₂ 270. CO₂H H H H H NH(CH₂)₃OH 271 CO₂CH₃ H H H H NH(CH₂)₃OH 272 CF₃ H H H H NHCH(CH₃)CH₂OH 142–143 273 AcNH H H H H NHCH(CH₃)CH₂OAc 163 274 CH₃ H H H H NHCH(CH₃)CH₂OH 80–81 275 CH₃ H H H H NHCH₂CH₃ 276 OCF₂CHF₂ H H H H NHCH₂CH₂OH 277 Cl H H H H

201–205 278 Cl H H H H NHN(COCH₃)₂ 210 279 Cl H H H H

166–167 280 Cl H H H H NHCH₂CH₂CH₂OCOOCH₂CH₃ 148–150 (d) = under decomposition; CN = compound number

Biological Examples

Using the biological assays B-1 to B-12 described above, the tests are carried out employing compounds, or their salts, from Table 59 given above. Plus “+” in the following table means that the activity observed in the corresponding test system is 70% or more.

TABLE 60 CN B1 B2 B5 B6 B7 B8 B9 B10 B11 B12 1 + 2 + + + 3 + + + 4 + + + + + 5 + + + 6 7 + + + 8 + + 9 10 11 12 + + + + + + + + 13 + + + + + + + 14 + + + + + 15 + + + + + + 16 + + + 17 18 19 + 20 + + + + 21 22 + 23 24 25 26 + + + + 27 + + + + 28 + + + + + 29 30 + + + + 31 + + + + + + + 32 + + + + + + + + 33 34 + + + + + 35 + + + + 36 + 37 + + + + + + + 38 + + + 39 + + + + + + 40 41 + + + 42 + + + 43 + + + + + 44 45 46 + + + + 47 48 + + + 49 + + + + 50 + + + + + + + 51 + + 52 + + 53 + 54 55 56 57 58 + + + + + + + + 59 + + + 60 + + + + + + 61 + 62 + + 63 + + + + + + 64 + + + + 65 + + + + + + + 66 + + + + + + + 67 68 + + + + + 69 + + + + + 70 + + + 71 + + 72 73 74 + 75 + + + + + + 76 + + 77 78 + 79 + + 80 81 + + + + 82 + + + + 83 + + + + 84 + + + 85 86 87 + + 88 89 90 + + 91 + + 92 93 + + + 94 + + + 95 + + + 96 + + + 97 + + + 98 + 99 100 + 101 102 + + 103 + + + 104 105 106 + + + 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 + + 122 123 124 125 + + + + 

1. A process for protecting a plant against attack or infestation by a phytopathogenic organism, comprising applying at least one compound of the formula I,

wherein n is 0 or 1, R₁ is halogen, alkoxy, haloalkyl, haloalkoxy or alkyl, R₂ is hydrogen, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy, each of R₃, R₄ and R₅ is, independently of the others, hydrogen, lower alkyl or halogen, and R₆ is a) hydrazino, that is unsubstituted or one- to threefold substituted by optionally substituted alkyl and/or optionally substituted acyl, b) cyclohexylamino, tetrahydro-4H-pyranyl-4-amino, pyrrolidine-3-amino, 2- or 3-tetrahydrofurylamino, all optionally substituted by amino, hydroxy, alkoxy, alkyl or alkoxyalkyl, c) piperazinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, alkoxy, alkyl or alkoxyalkyl, d) morpholinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, alkoxy, alkyl or alkoxyalkyl, e) oxazolidinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, f) thiazolidinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, g) imidazolidinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, h) amino or mono- or di-(lower alkyl)amino wherein the lower alkyl moieties are unsubstituted or substituted by one or more substituents independently selected from the group consisting of unsubstituted amino, N-mono- or N,N-di-(lower alkyl)-amino, (lower alkoxy)-lower alk-oxy, lower alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower alkylamino, cyano, halogen, oxo bound to a carbon that is not directly bound to a heteroatom, hydroximino, alkoximino, optionally substituted hydrazono, lower alkenyl, lower alkynyl, guanidyl, lower alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower alkanoylamino, halo-lower alkanoylamino, lower alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino, lower alkoxy-lower alkylaminocarbonylamino, amidino, di-lower-alkylamino-cyclohexyl, carboxy, lower alkoxycarbonyl, hydroxy-lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl, lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy, lower alkoxy-lower alkanoyloxy, carbamoyl, N-mono- or N,N-di-lower alkylcarbamoyl, N-(hydroxy-lower alkyl)carbamoyl, N-lower alkyl-N-hydroxy-lower alkyl-carbamoyl, N,N-di-(hydroxy-lower alkyl)-carbamoyl, N-hydroxy-carbamoyl, hydroxy, lower alkoxy, lower alkenyloxy, lower alkinyloxy, lower haloalkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxysilyl, 4-tetrahydro-4H-pyranyl, 3-pyrrolidinyl, 2- or 3-tetrahydrofuryl, 2- or 3-dihydrofuryl, piperazinyl, lower alkanoyl-piperazinyl, formylpiperazinyl, optionally substituted heteroaryl and optionally substituted heteroaryloxy, i) optionally substituted alkanoylamino, optionally substituted alkenoylamino, optionally substituted alkynoylamino, optionally substituted mono- or di-alkylaminocarbonylamino, optionally substituted alkoxycarbonylamino, optionally substituted mono- or di-alkylamino sulfonylamino, optionally substituted mono- or di-alkylaminosulfoxylamino, j) N-(optionally substituted alkyl)-N-(optionally substituted lower alkanoyl)-amino, k) N-(optionally substituted alkyl)-N-(optionally substituted alkoxycarbonyl)-amino, l) N-(optionally substituted alkyl)-N—(N′,N′-mono- or di-[optionally substituted alkyl]-aminocarbonyl)-amino, or m) N═C(R₇,R₈) wherein R₇ is hydrogen, alkyl, amino, mono- or di-alkylamino and R₈ is amino, mono- or dialkylamino or wherein R₇ and R₈, together with the binding carbon atom, form a saturated five- to seven-membered ring with 0, 1 or 2 ring nitrogen atoms that is optionally substituted by one or more substituents; or a salt thereof; to one or more loci selected from the group consisting of a plant, a part of a plant, seeds and the site of a plant.
 2. A process according to claim 1, wherein the phytopathogenic organism is a fungal organism.
 3. A process according to claim 1, wherein the fungal organism is one or more selected from the group of classes consisting of Ascomycetes, Basidiomycetes, Oomycetes and Fungi imperfecti.
 4. A process according to claim 1 wherein the phytopathogenic organism is a bacterium.
 5. A process according to claim 1 wherein the phytopathogenic organism is a virus.
 6. A process according to claim 1 wherein the phytopathogenic organism is a nematode.
 7. A process according to claim 1 wherein a compound of formula I is applied wherein n is 0 or 1, R₁ is halogen, haloalkyl or haloalkoxy, R₂ is hydrogen or alkyl, each of R₃, R₄ and R₅ is, independently of the others, hydrogen, lower alkyl or halogen, and R₆ is as defined in claim
 1. 8. A process according claim 1 wherein a compound of formula I is applied wherein n is 0 or 1, R₁ is halogen, haloalkyl or haloalkoxy, R₂ is hydrogen or alkyl, each of R₃, R₄ and R5 is hydrogen, and R₆ is as defined in claim
 1. 9. A process according to claim 1 wherein a compound of formula I is applied wherein n is 0 R₁ is chloro, trifluoromethyl, trifluoromethoxy or 1,1,2,2-tetrafluoroethoxy R₂, R₃, R₄ and R₅ are hydrogen, and R₆ is (a) hydrazino, that is unsubstituted or one- to threefold substituted by optionally substituted alkyl and/or optionally substituted acyl, (e) amino or mono- or di-(lower alkyl)amino wherein the lower alkyl moieties are unsubstituted or substituted by one or more substitutents independently selected from the group con-sisting of unsubstituted amino, N-mono- or N,N-di-(lower alkyl)-amino, (lower alkoxy)-lower alk-oxy, lower alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower alkylamino, cyano, halogen, oxo bound to a carbon that is not directly bound to a heteroatom, hydroximino, alkoximino, optionally substituted hydrazono, lower alkenyl, lower alkynyl, guanidyl, lower alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower alkanoylamino, halo-lower alkanoylamino, lower alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino, lower alkoxy-lower alkylaminocarbonylamino, amidino, di-lower-alkylamino-cyclohexyl, carboxy, lower alkoxycarbonyl, hydroxy-lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl, lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy, lower alkoxy-lower alkanoyloxy, carbamoyl, N-mono- or N,N-di-lower alkylcarbamoyl, N-(hydroxy-lower alkyl)carbamoyl, N-lower alkyl-N-hydroxy-lower alkyl-carbamoyl, N,N-di-(hydroxy-lower alkyl)-carbamoyl, N-hydroxy-carbamoyl, hydroxy, lower alkoxy, lower alkenyloxy, lower alkinyloxy, lower haloalkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxysilyl, 4-tetrahydro-4H-pyranyl, 3-pyrrolidinyl, 2- or 3-tetrahydrofuryl, 2- or 3-dihydrofuryl, piperazinyl, lower alkanoyl-piperazinyl, formylpiperazinyl, optionally substituted heteroaryl and optionally substituted heteroaryloxy, f) optionally substituted alkanoylamino, optionally substituted alkenoylamino, optionally substituted alkynoylamino, optionally substituted mono- or di-alkylaminocarbonylamino, optionally substituted alkoxycarbonylamino, optionally substituted mono- or di-alkylaminosulfonylamino, optionally substituted mono- or di-alkylaminosulfoxylamino, g) N-(optionally substituted alkyl)-N-(optionally substituted lower alkanoyl)-amino, h) N-(optionally substituted alkyl)-N-(optionally substituted alkoxycarbonyl)-amino, i) N-(optionally substituted alkyl)-N—(N′,N′-mono- or di-[optionally substituted alkyl]-aminocarbonyl)-amino, or j) N═C(R₇, R₈) wherein R₇ is hydrogen, alkyl, amino, mono- or di-alkylamino and R₈ is amino, mono- or dialkylamino or wherein R₇ and R₈, together with the binding carbon atom, form a saturated five- to seven-membered ring with 0, 1 or 2 ring nitrogen atoms that is optionally substituted by one or more substituents; or a salt thereof.
 10. A compound of the formula I,

wherein n is 1, R₁ is halogen, alkoxy, haloalkyl, haloalkoxy or alkyl, R₂ is hydrogen, halogen, alkyl, haloalkyl, alkoxy or haloalkoxy, each of R₃, R₄ and R₅ is, independently of the others, hydrogen, lower alkyl or halogen, and R₆ is a) hydrazino, that is unsubstituted or one- to threefold substituted by optionally substituted alkyl and/or optionally substituted acyl, b) cyclohexylamino, tetrahydro-4H-pyranyl-4-amino, pyrrolidine-3-amino, 2- or 3-tetrahydrofurylamino, all optionally substituted by amino, hydroxy, alkoxy, alkyl or alkoxyalkyl, c) piperazinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, alkoxy, alkyl or alkoxyalkyl, d) morpholinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, alkoxy, alkyl or alkoxyalkyl, e) oxazolidinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, f) thiazolidinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, g) imidazolidinyl that is optionally substituted by amino, amino-lower alkyl, hydroxy, hydroxy-lower alkyl, alkoxy, alkyl or alkoxyalkyl, h) amino or mono- or di-(lower alkyl)amino wherein the lower alkyl moieties are unsubstituted or substituted by one or more substitutents independently selected from the group consisting of unsubstituted amino, N-mono- or N,N-di-(lower alkyl)-amino, (lower alkoxy)-lower alkoxy, lower alkoxycarbonylamino, hydroxy-lower alkoxycarbonylamino, lower alkoxy-lower alkoxycarbonylamino, morpholinyl, hydroxy-lower alkylamino, cyano, halogen, oxo bound to a carbon that is not directly bound to a heteroatom, hydroximino, alkoximino, optionally substituted hydrazono, lower alkenyl, lower alkynyl, guanidyl, lower alkanoylamino, hydroxy-lower alkanoylamino, lower alkoxy-lower alkanoylamino, halo-lower alkanoylamino, lower alkylaminocarbonylamino, hydroxy-lower alkylaminocarbonylamino, lower alkoxy-lower alkylaminocarbonylamino, amidino, di-lower-alkylamino-cyclohexyl, carboxy, lower alkoxycarbonyl, hydroxy-lower alkoxycarbonyl, lower alkoxy-lower alkoxycarbonyl, lower alkylcarbonyldioxy (=lower alkoxycarbonyloxy), hydroxy-lower alkoxycarbonyloxy, lower alkoxy-lower alkoxycarbonyloxy, lower alkanoyloxy, halo-lower alkanoyloxy, hydroxy-lower alkanoyloxy, lower alkoxy-lower alkanoyloxy, carbamoyl, N-mono- or N,N-di-lower alkylcarbamoyl, N-(hydroxy-lower alkyl)carbamoyl, N-lower alkyl-N-hydroxy-lower alkyl-carbamoyl, N,N-di-(hydroxy-lower alkyl)-carbamoyl, N-hydroxy-carbamoyl, hydroxy, lower alkoxy, lower alkenyloxy, lower alkinyloxy, lower haloalkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxysilyl, 4-tetrahydro-4H-pyranyl, 3-pyrrolidinyl, 2- or 3-tetrahydrofuryl, 2- or 3-dihydrofuryl, piperazinyl, lower alkanoyl-piperazinyl formylpiperazinyl, optionally substituted heteroaryl and optionally substituted heteroaryloxy, i) optionally substituted alkanoylamino, optionally substituted alkenoylamino, optionally substituted alkynoylamino, optionally substituted mono- or di-alkylaminocarbonylamino, optionally substituted alkoxycarbonylamino, optionally substituted mono- or di-alkylaminosulfonylamino, optionally substituted mono- or di-alkylaminosulfoxylamino, j) N-(optionally substituted alkyl)-N-(optionally substituted lower alkanoyl)-amino, k) N-(optionally substituted alkyl)-N-(optionally substituted alkoxycarbonyl)-amino, l) N-(optionally substituted alkyl)-N—(N′,N′-mono- or di-[optionally substituted alkyl]-aminocarbonyl)-amino, or m) N═C(R₇,R₈) wherein R₇ is hydrogen, alkyl, amino, mono- or di-alkylamino and R₈ is amino, mono- or dialkylamino or wherein R₇ and R₈, together with the binding carbon atom, form a saturated five- to seven-membered ring with 0, 1 or 2 ring nitrogen atoms that is optionally substituted by one or more substituents; or a salt thereof. 